University of Helsinki

When Compliance Infrastructure Becomes a Security Object: Legal Reclassification between EU Supply Chain Due Diligence and China’s Order No. 834

Abstract Supply chain law increasingly renders global production governable through compliance infrastructure: supplier mapping, audit rights, traceability records, risk scoring, geolocation data, contractual monitoring, digital platforms and cross-border evidence flows. This art...

Understanding Newcomer Persistence in Social VR: A Case Study of VRChat

Newcomers are crucial for the growth of online communities, yet their successful integration into these spaces requires overcoming significant initial hurdles. Social Virtual Reality (VR) platforms are novel avenues that offer unprecedented online interaction experiences. Unlike...

An integrated spatially defined roadmap of normal and cancer-associated colon fibroblasts

Abstract Cancer-associated fibroblasts (CAFs) promote tumorigenesis and represent potential therapeutic targets, highlighting the need for precise understanding of CAF heterogeneity. In colorectal cancer (CRC), CAF subsets and nomenclature vary widely, and many studies overlook t...

Exposure to remote work and probability of long-distance commuting: evidence from pandemic lockdowns

Abstract In this paper, we investigate how the lockdown-induced exposure to remote work affected the likelihood of switching to longer commutes using a longitudinal full-population register of Swedish employees. We find that employees with little experience of longer commutes wer...

Who is Responsible for Tackling Professional Deskilling?

Abstract There has been increasing interest across several professional fields in problems of deskilling , that is, the loss or the lack of development of human skills due to outsourcing tasks to artificial intelligence. Avigail Ferdman (“AI Deskilling is a Structural Problem.” A...

Compensated Patient Injury Cases Due to Medication Errors in Finland During 2021 to 2023: A Cross-Sectional Register-Based Study

Objectives: To analyze follow-up data on medication errors (ME) in compensated patient claims in Finland from 2021 to 2023 and to discuss whether medication safety has improved since 2013 to 2014. Methods: This was a cross-sectional retrospective register-based study analyzing th...

Lifetime substance use disorder and suicidal behaviour: a population-based familial co-aggregation register study

Abstract Substance use disorders (SUD) are associated with suicidal behaviour, but less is known regarding the extent to which familial factors influence these associations across different types of SUD. We performed a national register study including 4,209,615 individuals born...

Poisson subspace clustering: focusing on the essentials in count data

Abstract Count data represented as a matrix of non-negative integer values, such as contingency tables, are prevalent across diverse domains. When clustering such data sets, specific methods are required, as generic algorithms often fail to consider their unique distributional pr...

JuRa: The Juventas Radar on Hera Mission to Probe Internal Structure of Didymos and Dimorphos Asteroids

Abstract JuRa, the Juventas Radar, is the sounding radar of the Hera/ESA mission on cruise to the asteroid Didymos and its moon, Dimorphos. In 2027, it will, for the first time, do direct observation of the internal structure of an asteroid for the benefit of both science and pla...

Gut microbiome maturation in early childhood interacts with host genetics to predict type 1 diabetes risk

Prospective evidence linking early-life microbiome development and host genetics with type 1 diabetes (T1D) risk is limited. Here, we describe how gut microbiome maturation and host genetics influence T1D risk in the TEDDY study. We analysed 12,151 longitudinal metagenomes and ho...

The structural political power of firms – and its boundaries

This article examines the conditional importance of structural power in determining firms’ political influence. While structural power derived from firms’ economic size has been widely theorised as a key determinant of business influence, it is argued here that its effect is high...

Genome-wide analysis of social behaviour across social domains, reporters and developmental stages: a meta-regression approach

Abstract Social behaviour is a heritable trait linked to well-being and mental health, yet it varies across social context, including social domains, informants and development, which may shape its underlying genomic architecture. Here, we conducted a genome-wide meta-regression...

Bedside infrared thermometry compared with continuous zero-heat-flux thermometry– an experimental and clinical study

This study compared standard infrared thermometers used in emergency rooms (ER) and wards to a Zero-Heat-Flux (ZHF) thermometry device and evaluated its feasibility for continuous bedside temperature monitoring. In 60 volunteers, five alternative ZHF sensor placements were assess...

From online traces to upstream surveillance: Large language models uncover the hidden status of non-native freshwater apex predators in China

Biological invasions are often recognised only after ecological damage has become visible in the wild, even though the human-mediated processes that drive introductions may already be underway through private rearing, trade, and release. This gap in upstream surveillance is espec...

School principals' burnout trajectories: Nature, predictors, and outcomes

This study seeks to achieve a dynamic person-centered understanding of the distinct burnout trajectories observed among 1574 Finnish school principals measured five times over a period of four years. Our results revealed that burnout trajectories corresponded to five main profile...

The farrowing sow: to confine or not confine

Abstract Background The aim of this study was to examine the effect of different temporary uses of farrowing crates and free farrowing on farrowing duration and piglet survival and growth under normal production conditions. The study included three farrowing systems on two farms:...

Sticky edtech: enacting postdigital platform realities in lower secondary schools

This article addresses the micropolitics of platformisation by exploring the affective dynamics between students, devices, and digital platforms in two lower secondary schools in the Nordic countries. Platformisation is at the core of contemporary edtech, constituting a central p...

SLC7A6OS Founder Mutation: A Rare Cause of Progressive Myoclonus Epilepsy Dated to 1100 Years Ago

BACKGROUND: SLC7A6OS c.191A>G is a rare, autosomal recessive cause of progressive myoclonus epilepsy (PME). The c.191A>G variant, first discovered in two families from Türkiye and Portugal, was recently identified in three additional probands from the USA, all of Puerto Rican anc...

α-Parvin regulation of cell rearrangement is critical for ureteric bud branching morphogenesis

All branched tubular structures, including the kidney collecting system, are formed by branching morphogenesis, a process that includes tip branching and trunk narrowing. Tight control of cell movement and rearrangement is a prerequisite for branching morphogenesis. The role of i...

Fast and Flexible Flow Decompositions in General Graphs via Dominators

Multi-assembly methods rely at their core on a flow decomposition problem, namely, decomposing a weighted graph into weighted paths or walks. However, most results over the past decade have focused on decompositions over directed acyclic graphs (DAGs). This limitation has led to...