University of Edinburgh

Joint Modeling of GD-1 and C-19 as Old Streams

Abstract DESI observational data for the GD-1 and C-19 streams are compared to stream simulations in an evolving multihalo potential of a Milky Way–like galaxy based on a cosmological Milky Way–like simulation. The number of subhalos decreases with time, and the subhalo-stream en...

Dilaton physics from asymptotic freedom

The dilaton is investigated from first principles within an asymptotically free Gross-Neveu-Yukawa theory in three dimensions. In the limit of many fermion flavours, the theory features a finite line of strongly interacting fixed points. At its endpoint, a dilaton arises as the m...

Parallel-in-Time Preconditioning for Time-Dependent Variational Mean Field Games

Abstract We study the numerical approximation of a time-dependent variational mean field game system with local couplings and either periodic or Neumann boundary conditions. Following a variational approach, we employ a finite-difference discretization and solve the resulting fin...

Intersecting Identities: How Gender and Disability Shape Voter Perceptions of Election Candidates

Voters’ perceptions of election candidates are known to be shaped by stereotypes about candidates’ characteristics and social identities, including gender and disability. More recently, scholars have started paying attention to how the intersection of politicians’ identities shap...

Generalisability of an adult-trained AI model to paediatric coeliac disease diagnosis: a multicentre external validation study

Background Coeliac disease diagnosis on duodenal biopsies is limited by interobserver variability. We have previously demonstrated pathologist-level performance with our artificial intelligence (AI) model for the histopathological diagnosis of adult coeliac disease, but not in pa...

Co-developing the Child and Adolescent Mentally Healthy Classroom (CAMH Class) intervention for use in routine teaching in secondary schools

Addressing the mental health needs of children and young people requires integrated and multidisciplinary action to reduce the risk of detrimental outcomes. Schools offer a unique environment for such provision. However, there is a critical need for school-based interventions tha...

Natural capital: the boom and bust of a metaphor? Insights from Scotland

Despite a fifty-year academic history, the concept of ‘natural capital’ has only been translated into national policy and practice more recently. Since the early 2000s, global initiatives like The Economics of Ecosystems and Biodiversity and the UN System for Environmental Econom...

Coordinated transformations of the labyrinth and occiput during the dinosaur–bird transition

Evolutionary shape changes of the vertebrate semicircular canals (SCCs) are often ascribed to evolutionary transitions in locomotion, including the origin of flight during the dinosaur–bird transition. However, the potential for transformations of braincase architecture to influe...

Exploring transcriptomic and genomic latent variable correction approaches in differential expression analysis

Abstract Background Differential expression analysis is a central tool for studying the biological processes altered in human diseases via transcriptomic signatures. However, transcriptomic datasets are systematically confounded by latent variables from two distinct sources: unme...

Implementation and Process Evaluation of a Programme to Promote Reading Motivation and Engagement: Love to Read Reception

ABSTRACT Background In the United Kingdom, continued declines in children's reading enjoyment and engagement have led to an urgent need for research‐informed, school‐based pedagogy to promote reading. This article shares findings from the implementation and process evaluation (IP...

An ‘Empty’ [Fe 16 ] Cage and its Transformation into [Fe 17 ] and [Fe 30 ]

ABSTRACT Polymetallic clusters of Fe III constructed without organic bridging ligands are an emerging class of molecules with structures akin to iron oxide minerals, possessing large spin ground states and/or displaying spin frustration effects. All previous examples, [Fe 8 ], [F...

Cardiac Myosin‐Binding Protein C for Diagnosis of Myocardial Infarction in Patients With Prior Coronary Artery Bypass Grafting

Background Diagnosing myocardial infarction in patients with prior coronary artery bypass grafting (CABG) remains challenging, primarily because of lower diagnostic accuracy of high‐sensitivity cardiac troponin (hs‐cTn). cMyC (cardiac myosin‐binding protein C), because of its fas...

Recycling and Reprocessing of Flax/Acrylic Biocomposites: A Dissolution Method Using Acetone as Solvent and Water as Non-Solvent

This study explores the second-generation biocomposites utilising flax fabric reinforcement with liquid thermoplastic Elium® (acrylic) resin. The surface tension and wettability of the liquid acrylic resin with flax fabric were characterised through experimental techniques. Subse...

Detection of Legionella Bacteria Using a Silicon‐Based Photonic Microring Resonator Biosensor Enhanced by Dielectrophoresis

Silicon-based photonic biosensors, such as microring resonators and Mach-Zehnder interferometers, offer label-free detection, high sensitivity, and full compatibility with semiconductor fabrication processes. Yet, the detection of living bacteria remains difficult due to the limi...

Adenylyl Cyclase 9: A Maverick Signalling Act in Search of Plots

Cryo-electronmicroscopy has revolutionized the study of integral membrane proteins. In the case of adenylyl cyclase 9 (AC9)—one of nine transmembrane paralogues in mammals that produce the ubiquitous intracellular messenger cyclic AMP—the technique was instrumental in revealing t...

Data benefits? Attitudes and aspirations of recipients towards social security administrative data sharing

This paper outlines benefit recipients’ views towards the sharing of data that is collected about them when they routinely interact with social security services. Sharing this administrative data between public bodies promises to transform the delivery and evaluation of social se...

Pysammos 1.0.0: a discrete-to-continuum transformation Python tool to analyse the rheology of granular materials

Abstract. Granular flow processes involving different interstitial fluids and coupling regimes are widespread in both natural systems (e.g., landslides, rock avalanches, river sediment transport) and industrial applications (e.g., aggregates in concrete manufacturing, powder tech...

EARLY RECOGNITION OF LIMB NECROTIZING FASCIITIS AND SURGERY WITHIN SIX HOURS IS ASSOCIATED WITH A LOWER MORTALITY RISK AND IMPROVED PATIENT-REPORTED OUTCOMES

Necrotising fasciitis (NF) is a rapidly progressive surgical emergency. The effects of time from hospital presentation to theatre on short- and long-term outcomes, as well as specific modifiable aspects of the care pathway that would enable early surgery, remain poorly defined. A...

PARIS (POSTERIOR MALLEOLUS RADIOLOGICAL INVESTIGATION STUDY): STANDARDIZING MANAGEMENT OF UNSTABLE ANKLE FRACTURES WITH A POSTERIOR MALLEOLUS COMPONENT

The PARIS algorithm is used to classify posterior malleolar fractures (PMF) and guide fixation planning based on plain radiographs, with reassessment following pre-operative computed tomography (CT). This study aimed to validate and optimise the PARIS algorithm to determine which...

A BN-Isostere of a Porous Organic Polymer Using Azabora-Spirobifluorenes

Abstract Porous organic polymers that can be processed using organic solvents are attractive materials for a range of applications. Switching a CC unit for an isoelectronic BN unit is a powerful method to modulate the key properties of organic polymers; however, this approach is...