University of Edinburgh

Anisotropy of Satellite Galaxies. I. Contrasting Correlations with Central Galaxy, Host Halo, and Large-scale Filament Structures

Abstract Using the SIMBA, EAGLE, and IllustrisTNG-100 galaxy formation simulations, we examine the anisotropy of the satellite distribution and its dependencies on central galaxies, host halos, and cosmic filaments. We find that in all simulations, the satellite anisotropy is rob...

AutoEmulate: A PyTorch tool for end-to-end emulation workflows

Computational simulations lie at the heart of modern science and engineering, but they are often slow and computationally costly. A common solution is to use emulators: fast, cheap models trained to approximate the simulator. However, constructing these requires substantial exper...

A Scoping Review of Virtual Reality in Blue Space Research

This study aims to systematically review the current applications and development trends of virtual reality (VR) technology in blue space research. It clarifies the main research methods, technical pathways, application scenarios, and existing knowledge gaps, and integrates the a...

Deconstructing the Black Box of Entrepreneurial Team Resilience Formation: A Multi-case Study from a Process Perspective

Entrepreneurial teams frequently face adversity, yet their resilience outcomes vary from failure to recovery and even growth beyond recovery. While prior research views resilience as a process and highlights the role of team psychological resources, it remains unclear how team in...

Viperin as a putative antiviral effector in rainbow trout (Oncorhynchus mykiss) cells identified by CRISPR-Cas9 functional analysis following exposure to inactivated viral hemorrhagic septicemia virus

Abstract Viperin is recognized for its potent broad-spectrum antiviral activity; however, its role in the antiviral immune response of rainbow trout ( Oncorhynchus mykiss ) remains poorly characterized. In this study, the contribution of viperin to the innate immune response agai...

High‐Pressure Synthesis of Quantum‐Stabilised Manganese Superhydride MnH 7

ABSTRACT Through high‐temperature, high‐pressure diamond anvil cell studies combined with in situ synchrotron powder x‐ray diffraction, we investigate the reactivity between manganese and hydrogen up to 182 GPa. Laser heating manganese in an medium at 118 GPa yields body‐centred...

Integrated technologies of care: proof-of-concept study on an integrated physiological and activity monitoring system to enhance independence and care

Abstract This study presents a multi-sensor activity monitoring system designed to verify daily behaviours and detect physiological anomalies within a controlled home environment. Seven subjects participated in a scripted routine of Activities of Daily Living carried out in a hom...

Cross‐domain sustainability preferences in clothing and food: Evidence from environmental attitudes, stated confidence in producers claims and willingness‐to‐pay measures

Abstract Background Sustainability attributes increasingly feature in consumer products, but it remains unclear whether environmental and ethical preferences are consistent across clothing and food choices. Aims This study examines how environmental attitudes, stated choices and...

High‐Pressure Synthesis of Quantum‐Stabilised Manganese Superhydride MnH 7

ABSTRACT Through high‐temperature, high‐pressure diamond anvil cell studies combined with in situ synchrotron powder x‐ray diffraction, we investigate the reactivity between manganese and hydrogen up to 182 GPa. Laser heating manganese in an medium at 118 GPa yields body‐centred...

RNA degradation by DIS3 is a necessary step in the resolution of backtracked transcription complexes

Summary The RNA exosome is known to participate in transcription, but the contribution of its ribonuclease activities to this process remains unclear. Here we investigated the role of DIS3, one of the exosome ribonucleases, in transcription by RNA polymerase II (RNAPII). Rapid de...

Educational approaches to teach the 2017 periodontal classification to dental healthcare professionals: A scoping review

Abstract Background Diagnostic errors are a major concern, particularly when long‐standing diagnostic criteria are updated. Following the 2017 World Workshop on the Classification of Periodontal and Peri‐implant Diseases and Conditions, a new classification was released in 2018....

Strategic design of methane observation networks to improve emission estimates: A case study in Africa

Abstract. Ground-based and satellite atmospheric observations are essential for reducing uncertainties in methane (CH4) emissions by atmospheric inversion, particularly in data-sparse regions such as Africa. However, adding new observation sites does not yield linear improvements...

Celestial amplitudes on electromagnetic backgrounds: T-duality from S-duality

Abstract What is the boundary holographic dual of S-duality for gauge theories in asymptotically flat space-times? Celestial amplitudes, by virtue of exhibiting holographic properties of the S-matrix, appear well-suited for studying this question. We scatter electrically and magn...

Science as a global public good: responding to challenges of the modern era

Abstract Science has been crucial to the creation of the modern world and is essential in navigating its complexities. Well-informed citizens, willing to change perspectives in the face of new evidence, are essential to democracy. Recognizing science as a global public good, free...

PPAD-Membership for Problems With Exact Rational Solutions: A General Approach via Convex Optimization

Abstract. We introduce a general technique for proving membership of search problems with exact rational solutions in PPAD, one of the most well-known classes containing total search problems with polynomial-time verifiable solutions. In particular, we construct a “pseudogate,” c...

The Association Between Chronic High-Altitude Exposure and Increased Pulmonary Vascular Resistance in Healthy High-Altitude Residents: A Systematic Review and Meta-Analysis

00:00-00, 2026. BACKGROUND: At high altitude, hypoxia triggers pulmonary vasoconstriction and vascular remodeling, potentially elevating pulmonary vascular resistance (PVR). Whether chronic high-altitude exposure raises PVR to clinically meaningful levels remain unclear, particul...

Cardiovascular effects of chemoradiotherapy in patients with lung cancer: an [18F]FDG PET-CT imaging study

Abstract Background Cardiovascular and pro-atherogenic side-effects of chemoradiotherapy for non-small cell lung cancer (NSCLC) remain a major concern given the growing burden of cancer therapy-related cardiovascular disease. Atherosclerotic plaque burden can be measured using ca...

Sulforaphane Decreases the Burden of AKT1-Expressing Pre-Neoplastic Cells in a Zebrafish Model of Glioblastoma Initiation

Background: Glioblastoma is a primary aggressive brain tumor, with an average survival rate of ~14.6 months. The low therapeutic benefit of current treatments is in part due to glioblastoma-initiating cells hijacking microglia/macrophages to support tumor growth, prompting the de...

Integrable models from 4d holomorphic BF theory

We show how to construct 2d field theories with holomorphic integrability from defect setups in 4d holomorphic BF. In a simple example setup, we explicitly construct the 2d theory and perform an initial classical analysis. Making use of the symmetries, we are able to write down a...

Acceptability of advanced Controlled Human Infection Models: The case of a pneumococcal challenge in people living with HIV and mycobacterial challenge with Bacillus Calmette Guerin in Malawi

Abstract Background Controlled Human Infection Models (CHIM) in which volunteers are experimentally exposed to pathogens are used to study pathogenesis and down select among treatment and vaccine candidates. Scientifically, CHIM studies are best conducted among at-risk population...