University of Edinburgh

Translational evidence for the antihypertensive potential of Passiflora edulis: a systematic review of preclinical and clinical studies

Abstract Introduction Passiflora edulis (PE) (passion fruit) is traditionally valued for its cardiovascular and calming properties, but its antihypertensive and blood pressure (BP)-lowering potential has not been systematically evaluated. Emerging evidence from preclinical and cl...

Evidence of a massive accretion event 1.8 billion years before the Gaia-Sausage-Enceladus merger

Abstract The merger history of the Galaxy has been traced back firmly to a redshift of 2 (10 billion years ago). While evidence for the existence of at least one more substantial merger before this time has been presented, its interpretation is yet to be fully established. Here w...

Ketosis as a Treatment for Severe Mental Illness: A Critical Review of Preclinical and Clinical Data

Abstract Purpose Ketogenic interventions, including ketogenic diets, are increasingly being explored as potential treatments for severe mental illnesses. Ketosis – the metabolic state characterised by high circulating levels of ketone bodies – is thought to be central to the bene...

Effect of chronic high‐altitude hypoxia on retinal vascular phenotype, choroidal and retinal vasoreactivity in Peruvian highlanders

Abstract High‐altitude chronic hypoxia can induce excessive erythrocytosis (EE, defined as a haemoglobin concentration of ≥21 g/dL in men), leading to hyperviscosity and promoting endothelial dysfunction. We aimed to assess whether EE affects the retinal vascular phenotype and th...

Programming Ion‐Engineered Interphase for Practical Zinc Batteries Through Exogenous Cation‐Anion Synergy Chemistry

ABSTRACT A stable anode‐electrolyte interface is vital for battery cycling. Translating the successful anion‐derived interphase paradigm from Li‐ion to aqueous Zn‐ion batteries (ZIBs) is hindered by narrow electrochemical windows and chaotic interfacial reactions. Here we overcom...

Dynamic memory in rodent C‐fibres and its impact on spinal nociceptive processing

C-fibre nociceptors display low-level spontaneous firing in the context of tissue injury. Microneurography studies have demonstrated that such low frequency firing can dynamically regulate the activity-dependent slowing (ADS) or temporal pain signal relay of C-fibre nociceptors,...

Young people’s resistance within and against unjust systems: The possibilities and challenges of participatory action research-enabled social innovation and social entrepreneurship

This article establishes a dialogue between the fields of participatory action research, social innovation and social entrepreneurship, by presenting learning from two projects with young people in Colombia and critically situating it within intersectional, intergenerational and...

Homicide at home: setting the agenda for an international collaboration to improve support for children bereaved due to family violence

Background: Bereavement due to fatal family violence (e.g. intimate partner homicide, filicide, parricide, siblicide) is a profoundly disruptive experience for children, with lifelong psychosocial consequences. Although the need for fatal family violence prevention is increasingl...

Eating Disorder Focused Family Therapy with Autistic Children and Young People: A Narrative Review of Recent Developments

Abstract Purpose of review This review aims to report the recent advances for eating disorder focused family therapy (FT-ED) for Autistic children and young people, including outcomes, experiences, and suggested adaptations. Recent findings Quantitative studies suggest that Autis...

European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) guidelines for antimicrobial and non-steroidal anti-inflammatory drug use in bovine respiratory disease

<ns5:p> Background Bovine respiratory disease (BRD) is a major cause of morbidity, mortality, impaired welfare, production loss, and antimicrobial use in cattle. These European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) guidelines provide evidence-based...

Critical Pedagogy of Multicultural Incorporation

Abstract This article brings cultural sociology, civil sphere theory, and critical theory into dialogue to examine the empirical-cum-political stakes of education in multicultural societies. Using a mixed-methods approach, it analyzes school cultures in Finland, Scotland, and Swe...

Programming Ion‐Engineered Interphase for Practical Zinc Batteries Through Exogenous Cation‐Anion Synergy Chemistry

ABSTRACT A stable anode‐electrolyte interface is vital for battery cycling. Translating the successful anion‐derived interphase paradigm from Li‐ion to aqueous Zn‐ion batteries (ZIBs) is hindered by narrow electrochemical windows and chaotic interfacial reactions. Here we overcom...

Restriction of access to means of suicide in veterinary workplaces: Protection, unintended consequences and complexity

BACKGROUND: Workplace access to means of suicide has been theorised as a contributor to elevated veterinary suicide rates. Workplace interventions to reduce suicide deaths among veterinary professionals require understanding of how restriction of access is experienced. METHODS: Q...

Plant species identification by genome skimming across the vascular plant tree of life

Summary Accurate species identification is essential for biodiversity conservation and sustainable use, yet standard plant DNA barcoding often fails to achieve species‐level resolution. We present a large‐scale empirical evaluation of genome skimming as a tool to improve plant sp...

Perceptions of death, grief and loss in adolescents experiencing non-terminal maternal cancer: a secondary qualitative data analysis

Purpose A diagnosis of parental cancer, even if not terminal, can have a significant and adverse impact on adolescents' lives marked by significant non-death related loss. Research identified that adolescents experiencing parental cancer terminal and non-terminal both exhibited s...

Biogeochemical Control of Hydrogen–Iron Minerals Interfacial Chemistry in Subsurface Energy Systems

Abstract Microbial processes are increasingly recognized as critical modifiers of solid–fluid interfaces in subsurface systems; however, their role in hydrogen–mineral interfacial chemistry remains poorly constrained. Here, we demonstrate that microbial colonization fundamentally...

Phong‐Rodrigues Extrinsic Vector‐Field Processing

Abstract We introduce a new extrinsic discretization of tangent vector fields on triangle meshes that is continuous, with bounded derivatives that are continuous almost everywhere, supporting pointwise evaluation and integration of differential operators. We achieve this by build...

ODARRL: Obstacle- and Disturbance-Aware End-to-End Residual Reinforcement Learning for Underwater Robot Trajectory Tracking with Obstacle Avoidance

ROVs are essential for marine exploration and underwater operations, yet conventional teleoperation relies heavily on skilled human operators, and many autonomous methods stop at high-level planning rather than low-level actuation, limiting robustness in disturbed and cluttered e...

Adherence to the Eatwell Guide and associations with markers of adiposity: a prospective analysis within the UK Biobank cohort

Abstract Background Obesity remains a major public health concern in the UK, contributing towards increased disease risk and premature mortality. The Eatwell Guide - the UK’s health eating model - is widely applied in policy and practice, yet evidence linking adherence to this di...

Quaternary Arctic planktonic foraminifera: morphological differentiation and taxonomic reassessment of subpolar spinose taxa

Abstract. Planktonic foraminifera in the modern Arctic Ocean are dominated by the non-spinose polar species Neogloboquadrina pachyderma. Acmes of two spinose, presumed subpolar taxa in Quaternary central Arctic sediment cores are therefore anomalous, implying significantly differ...