Institution
University of Chicago
Recent research
- Engineering & Technology
Abstract We designed hybrid aggregate model systems with cascade energy alignment from conjugated polymers (CPs) to quantum dots (QDs) to investigate the effects of QDs on CP singlet (S1) excitons. Radiative recombination of S1 excitons occurs within 1 ps in the chlorinated CP/QD...
- Biology
siRNA‐Loaded Metal‐Organic Layers for Targeted Gene Silencing and Radiotherapy Enhancement
ABSTRACT Radiotherapy (RT) remains a cornerstone in cancer treatment; however, its therapeutic efficacy is often limited by tumor fibrosis and radioresistance, primarily driven by transforming growth factor‐β (TGF‐β) upregulation. To address these challenges, we developed a tris(...
- Health & MedicineOpen access
Letter to University of Montreal – Address to Our Supervisors Team
In this paper, We are addressing a note to University of Montreal, mainly our Supervisors : Professor [bilodeau@dms.umontreal.ca],Professor [duchesne@dms.umontreal.ca], and Professor [murua@dms.umontreal.ca], Professor Perron [perronf@dms.umontreal.ca],Professor David [dhaziza@uo...
- Health & MedicineOpen access
Letter to University of Montreal – Address to Our Supervisors Team
In this paper, We are addressing a note to University of Montreal, mainly our Supervisors : Professor [bilodeau@dms.umontreal.ca],Professor [duchesne@dms.umontreal.ca], and Professor [murua@dms.umontreal.ca], Professor Perron [perronf@dms.umontreal.ca],Professor David [dhaziza@uo...
- AI & ComputingOpen access
Workers shift their views and pay more when AI chatbots pander to their values
Abstract Large language models (LLMs) are increasingly embedded in knowledge work, raising the question to what extent they can systematically influence their users’ decisions—a question with commercial as well as societal stakes. Across an exploratory study and two pre-registere...
- Engineering & TechnologyOpen access
Structure of Li3YCl6 and Its Effect on Lithium Ionic Conductivity
Abstract Halide-based Li+ solid-state electrolytes have garnered renewed interest in recent years, mainly because of their significantly improved Li+ ionic conductivity and excellent stability against high-voltage cathodes. Numerous studies have reported that synthetic conditions...
- Health & MedicineOpen access
Federal Funding Cuts and the Future of Health Care in Schools
This Viewpoint discusses threats to and protections for school-based health services.
- Health & MedicineOpen access
Abstract Background Tobacco use is a leading cause of premature mortality among people living with HIV (PLWH), especially in Botswana, where high smoking rates coincide with successful HIV control. There is a need for evidence-based interventions to support smoking cessation amon...
- Health & MedicineOpen access
m6A mRNA methylation regulates pancreatic α-cell plasticity
Pancreatic α-cells are central regulators of glucose and amino acid homeostasis, yet the mechanisms that preserve α-cell identity and function remain incompletely understood. N6-methyladenosine (m6A) is a widespread mRNA modification that is essential for β-cell biology and pancr...
- Materials & EnergyOpen access
Abstract Salt accumulation and surface fouling remain major barriers to long-term solar-driven interfacial evaporation. Here we report a geometry-engineered Janus electrospun membrane that integrates asymmetric wetting with structural design to suppress salt buildup. The membrane...
- Climate & Environment
Abstract Integrating neontological and paleontological information improves inferences about the tempo and mode of phenotypic evolution over long timescales. However, outside a few exemplar clades, morphological matrices establishing formal phylogenetic placements of fossils with...
- Health & MedicineOpen access
The next-generation biomarkers in early-stage triple negative breast cancer
PURPOSE OF REVIEW: Despite maximal neoadjuvant chemoimmunotherapy, nearly 40% of early-stage triple-negative breast cancer (TNBC) patients fail to achieve pathological complete response, underscoring an urgent need for biomarkers capable of guiding treatment modulation. This revi...
- BiologyOpen access
Abstract Tuberculosis (TB) is again the world’s leading cause of death from a single infectious agent. Aminoacyl-tRNA synthetases are essential for protein synthesis and are promising drug targets because bacterial and human enzymes differ. We repurposed a human prolyl-tRNA synth...
- Engineering & Technology
Anion and Cation (Co-)intercalation Behavior from an Inorganic Molten Salt for Dual-Ion Batteries
Abstract Long-duration energy storage is needed to accelerate decarbonization. Lithium-ion batteries are currently state-of-the-art but require costly transition metal oxide cathodes, which can limit their scalability. Dual-graphite batteries are a promising chemistry featuring a...
- Materials & Energy
Abstract Dynamic modulation of the electronic environment of catalytic active sites offers a promising route to overcome the limitations of static catalyst design. One possible direction to achieve this goal is to induce catalyst dynamics via rapid inversion of the surface dipole...
- BiologyOpen access
Skilled, goal-directed movements exhibit trial-to-trial variability even in experts, particularly in response to dynamic environmental conditions or when perfect repetition is not required for success. Identifying where, to what extent, and how stably this variability is encoded...
- BiologyOpen access
Conspectus Phase separation of various materials has been studied for one and a half centuries, laying foundational principles in materials science. In the last two decades, phase separation of proteins and nucleic acids has received enormous attention, due to its relevance to ce...
- Health & Medicine
BACKGROUND: High-grade astrocytoma with piloid features (HGAP) is a recently defined tumor type that is not well-understood. Prognostic factors of clinical outcomes are not well-established. METHODS: Methylation profiling was performed on tumor samples, many at the National Cance...
- Health & MedicineOpen access
Despite national and international recommendations for exclusive breastfeeding to 6 months of age, 44% of infants receive no breastmilk at this important milestone, imposing a significant cost on the US economy vis a vis elevated cardiovascular, infectious, and metabolic disease...
- Materials & EnergyOpen access
Large-volume serial electron microscopy enables reconstructions of neural circuits at synaptic resolution but depends on reliable collection of large libraries of ultrathin sections. Here, we present a low-cost protocol for direct wafer-based section collection. We describe steps...