Institution
University of California, Berkeley
Recent research
- AI & ComputingOpen access
Semi-pessimistic Reinforcement Learning
Offline reinforcement learning aims to learn an optimal policy from pre-collected data. However, it faces challenges of distributional shift, where the learned policy may encounter unseen scenarios not covered in the offline data. Additionally, numerous applications suffer from a...
- Engineering & TechnologyOpen access
The AWAKEN wind farm benchmark – Part 2: Modeling results
Abstract. Accurately modeling wind farm performance in complex atmospheric flows remains a challenge. This paper presents the modeling results of the American WAKE experimeNt (AWAKEN) wind farm benchmark, a collaborative effort involving 16 research groups from academia and indus...
- Engineering & TechnologyOpen access
BeyondMimic: From motion tracking to versatile humanoid control via guided diffusion
The humanlike form of humanoid robots uniquely positions them to achieve the agility and versatility in motor skills that humans have. Learning from human demonstrations offers a scalable approach to acquiring these capabilities. However, prior works either produced unnatural mot...
- BiologyOpen access
Approaching an unknown communication system by latent space exploration and causal inference
Abstract We propose a methodology for discovering meaningful properties in data without ground truth by combining manipulation of the latent variables of generative models to extreme values with causal inference in an approach we call causal disentanglement with extreme values (C...
- BiologyOpen access
Abstract Faithful chromosome segregation is essential for producing viable gametes during meiosis, a specialized type of cell division compared to mitosis. Unlike mitosis, meiosis involves two consecutive chromosome segregation events without an intervening round of DNA replicati...
- Engineering & Technology
Abstract The increasing occurrence of ground sinking in metropolitan cities due to excavation-induced backfill instability has raised significant safety concerns. Conventional compacted soils used for backfilling underground utilities often fail to provide adequate support, leadi...
- Society & EconomicsOpen access
The Salience of Entrepreneurship: Evidence from Online Business
We examine the decision to become an entrepreneur in the context of online business. Using data on entrepreneurs from a large e-commerce marketplace in China, we find that individuals are more likely to start online businesses after observing the salient success of nearby stores....
- Health & Medicine
BACKGROUND: Social isolation is associated with poor physical health and premature mortality. Midlife and older adults who use stimulants (cocaine or methamphetamine) may be especially vulnerable to social isolation. METHODS: We conducted in-depth semi-structured interviews with...
- Physics & SpaceOpen access
Abstract The Long-Integration Magnetar Burst Observatory (LIMBO) is a real-time radio transient detection pipeline designed to search for dispersed fast radio bursts (FRBs) from Galactic magnetars. LIMBO employs a 4.3-m dish with a dual-polarization feed to continuously monitor a...
- Physics & SpaceOpen access
Abstract We present a multiwavelength study of the long-duration gamma-ray burst GRB 230328B, combining prompt γ-ray observations with exceptionally early simultaneous optical photometry and extensive X-ray, radio, and host-galaxy follow-up. NUTTELA-TAO began simultaneous g′r′i′...
- BiologyOpen access
During photosynthetic water oxidation, the Mn4Ca cluster in Photosystem II progresses through five intermediate Si (i = 0–4) states. X-ray crystallography studies have reported the insertion of one new O ligand during the formation of the S3 state, but recent studies question the...
- AI & ComputingOpen access
The perils of omitting omissions when modeling evidence accumulation
Response deadlines are commonly imposed in decision-making research to incentivize speedy decisions and sustained attention. This procedure frequently leads to a proportion of trials in which no response is made, and these omissions are often simply removed from the data during a...
- Materials & EnergyOpen access
LinkLlama: Enablinga Large Language Model for ChemicallyReasonable Linker Design
Fragment-based drug discovery (FBDD) relies heavily on the design of chemically viable linkers to connect fragments binding to different pocket regions into potent lead molecules. While recent generative models have advanced spatial fragment linking, they frequently produce linke...
- Health & MedicineOpen access
BACKGROUND: The D3-creatine (D3Cr) dilution method provides a non-invasive and accurate assessment of muscle mass. Our objective was to examine the relationship between D3Cr muscle mass, objective measures of physical performance, and self-report physical function postmenopausal...
- Engineering & Technology
Isothermal Captureand Release of Carbon Dioxide witha Porous Molecular Hexaamine
Abstract The decarbonization of fossil fuel combustion streams and air is imperative to achieve negative carbon emissions and requires discovery of new materials that exhibit high CO2 capacities, long-term stability, and minimal energy input for the release of pure CO2. Numerous...
- Health & MedicineOpen access
The immunophenotype and proviral landscape of HIV-infected CD4 T cells during antiretroviral therapy
In individuals on effective antiretroviral therapy, integrated HIV proviruses persist within CD4 T cells, forming a viral reservoir that rebounds if treatment is stopped. Identifying and targeting these rare, infected cells is critical for advancing therapies, but methods to stud...
- Engineering & TechnologyOpen access
Non-local physics-informed neural networks for forward and inverse solutions of granular flows
Abstract Dense granular flows exhibit nonlocal effects due to stress transmission in microplastic events, especially in quasi-static or slowly sheared regions. Hence, traditional local rheological models fail to capture spatial cooperativity effects that are prominent in many gra...
- Health & MedicineOpen access
Abstract Although some symptoms of Parkinson’s disease can be pharmacologically alleviated, stopping disease progression is not currently possible. Motor impairment in Parkinson’s disease is associated with accumulation of aggregates of the protein α-synuclein (α-syn) in dopamine...
- Health & MedicineOpen access
Abstract Uridine 5′-diphospho-glucuronosyltransferase (UGT) enzymes play a critical role in hepatic and other metabolism of endogenous and exogenous small molecules. The addition of glucuronic acid via UGT increases the polarity and subsequent solubility of small molecules, helpi...
- Materials & EnergyOpen access
Abstract Nucleic acid–metal complexes, such as DNA-stabilized silver nanoclusters (DNA-AgN) and Ag(I)-mediated DNA duplexes, show promise for applications ranging from biomedical imaging to bioelectronics and sensing. Electrospray ionization mass spectrometry (ESI-MS) is a powerf...