Universidade do Porto

Portugal's health in all policies: A comprehensive review of legal frameworks

Introduction Health inequalities persist across Europe, highlighting the need for cross-sectoral strategies like Health in All Policies (HiAP). However, approaches to health and social policy vary across countries, implementation is difficult, and further evaluations are needed t...

Genomic signatures of historical pastoralism in Iberian livestock dogs

Livestock working dogs provide a powerful system for understanding how human cultural practices shape domestic animal genomes. Across Iberia, centuries of pastoralism and transhumance brought together dogs selected for distinct tasks, including livestock guarding and herding, yet...

Development of a Universal Thermosetting Putty for High-Performance Bicycle Frames: An Integrated Materials Engineering and Process Optimization Approach

The rapid expansion of the European e-bike market has increased demand for light-weight 6061 aluminum frames with premium cosmetic finishes, highlighting the need for thermally stable surface-leveling materials compatible with high-throughput powder coating. This study aims to de...

Community Pharmacy Involvement in Cardiovascular Patient Follow-Up: A Conceptual Framework for Integrated Ambulatory Pharmaceutical Care

Background/Objectives: Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide, requiring coordinated long-term management of cardiovascular risk factors, complex pharmacotherapy, and continuity of care across healthcare settings. Community pha...

On the Prediction of Ductile Fracture in Flexible Roll Forming

Fracture is one of the most common defects that occur during the roll forming process. However, several process-based strategies can be employed to minimize its occurrence. This paper investigates the fracture mechanisms of AA3105 aluminum alloy sheets during the flexible roll fo...

Trade fairs as relational network spaces: catalysing sustainable innovation. A study in the footwear industrial network

Purpose This paper aims to investigate how trade fairs (TFs), conceptualised as relational network spaces (RNS), catalyse sustainable innovation (SI) through changes in business relationship dynamics. It investigates how interactions at TFs stimulate SI at three analytical levels...

ERGA-BGE Reference Genome: Corema album ((L.) D. Don, 1830) - the Portuguese crowberry, endemic to the Iberian Peninsula.

Corema album is a perennial, dioecious shrub endemic to the Atlantic coast of the Iberian Peninsula and the Azores. It inhabits coastal dune ecosystems from Galicia to the Strait of Gibraltar, where it plays an important ecological role. The goal of this study was to assemble and...

Regional-Scale Multi-Hazard Assessment of Earthquake-Induced Road Network Disruption

Recent earthquakes have shown that earthquake-induced landslides and liquefaction can severely disrupt transportation systems and generate significant direct and indirect losses. Still, these secondary hazards are rarely incorporated into regional road-network disruption assessme...

Therapeutic inertia near the end of life in advanced cancer: a narrative review and framework

Advanced cancer requires repeated decisions about whether further cancer-directed treatment remains proportionate. This narrative review examines therapeutic inertia near the end of life, defined as treatment continuation or initiation by the treating team without explicit reasse...

CXCL9-driven immune rewiring and tumor-intrinsic ATR signaling inhibition restore radiotherapy response in lung cancer

Abstract Background Non-small cell lung cancer (NSCLC) accounts for ~ 85% of lung cancers and is associated with poor outcomes in advanced stages. Radiotherapy (RT) is central to NSCLC treatment, yet locoregional relapse remains frequent. Increasing evidence indicates that, beyon...

Effectiveness of interventions to prevent or treat prolonged grief symptoms among families of the patients who die in intensive care units: A systematic review and meta-analysis

Background Family members of ICU decedents are at high risk of adverse psychological outcomes, including prolonged grief. However, evidence regarding the effectiveness of existing family support interventions remains limited. Objectives To evaluate the effectiveness of interventi...

The elusive intertidal: Wave forms and coastal dynamics through architectural representation

Background This study combines cartographic sources with the situated knowledge of the local surfing community to address the lack of information describing intertidal zones in coastal areas, using the mouth of the Douro River as a case study. It employs architectural representat...

Critical mapping of evolution of distillery spent-wash research from treatment to resource recovery

ABSTRACT Infographic showing distillery wastewater research shifting from pollution control (1955-2010) to resource recovery (2011-present). Distillery spent wash is high organic-content wastewater with critical ecological impacts and unexplored potential for its valorization. Th...

Central nervous system manifestations in hereditary transthyretin amyloidosis: a cross-sectional study with 151 patients

Abstract Background Central nervous system (CNS) dysfunction is increasingly recognized in hereditary transthyretin (ATTRv) amyloidosis. We aimed to characterize CNS manifestations and assess associations with clinical variables and plasma neurofilament light chain (NfL), using h...

Using Match Reference Values of External Load to Monitor Performance and Fatigue in Football: Are We Looking the Right Way?

Abstract Monitoring external load is critical for informed decision-making processes across sports. In football, external load is routinely monitored during training sessions and competitive matches. Matches are typically given particular emphasis, as they are generally associate...

Children’s perceptions of natural history museums: Insights from the “Young Naturalists” program in Portugal

Children and adolescents are a key audience for scientific and cultural outreach and literacy. As future citizens, voters, and taxpayers, their education—carried out in formal, informal, and non-formal contexts—is crucial for societal development. In this context, scientific cult...

Resistant Candida spp. in Healthy Individuals: Mapping a Surveillance Blind Spot

The prevalence and characteristics of resistant, biofilm-forming Candida strains in healthy individuals remain poorly understood. In this work, Candida strains from 23 healthy volunteers and 11 candidiasis patients (n = 34) were isolated and characterized. Biofilm formation capac...

Identification of Combined Isotropic–Kinematic Hardening Parameters from Reverse Bending Tests Using Recurrent Neural Networks

Accurate identification of constitutive parameters is essential for reliable finite element simulations of sheet metal forming processes. Conventional inverse identification techniques, such as Finite Element Model Updating (FEMU), generally require iterative optimization procedu...

Characterization of the simulation technician profile in Portugal: a cross-sectional study

Abstract Background Effective simulation-based education (SBE) requires specialized technical expertise to manage increasingly complex equipment. While simulation technicians are recognized as vital to high-quality programs, their roles remain poorly defined internationally and u...

Global and Local Approaches Applied to Mode I Fracture Toughness Measurement of Bi-Material Bonded Joints

Nowadays, the application of different materials is quite common to optimise the performance of structural components. In this context, bonding between metals and composites becomes a frequent strategy. However, the appropriate design requires special care owing to the complex st...