Universidade do Porto

Do elite soccer players meet nutritional requirements? A scoping review and meta-analysis

This scoping review and meta-analysis synthesised current evidence on energy and macronutrient intake and energy expenditure in elite male and female soccer players. Despite established nutritional guidelines, concerns persist regarding chronic low energy availability and its imp...

Trichlorination by a single cyanobacterial halogenase in the biosynthesis of lebomboamide A

Halogenation is a widely used strategy, both in nature and medicinal chemistry, to modulate the properties of small molecules. Cyanobacteria are a rich source of halogenases that act regio- and stereoselectively on sp3-hybridized carbon centers, which have been reported to cataly...

Exploring the relation between childhood adversity and diabetes medication adherence: a cross-sectional study

Adverse Childhood Experiences (ACE) are associated with poor health outcomes, but their effect on the medication adherence of patients with type 2 diabetes (T2DM) remains unclear. This study aimed to assess the relation between ACE and medication adherence, while also exploring w...

Impaction and Mineralization Status of the Mandibular Third Molar: A Retrospective Study

Chronological age estimation is used in legal contexts to determine the transition between minor and adult status, with the third molar (3M) being a primary biological indicator. This retrospective study aimed to analyze the relationship between the topographic position of impact...

From Petro-Polymers to Biopolymers: Chitosan Strategies for Sustainable Hemodialysis

Hemodialysis (HD) remains the most widely adopted renal replacement therapy for patients with end-stage kidney disease; however, its delivery entails a substantial environmental burden due to high water and energy consumption and extensive reliance on single-use synthetic polymer...

Real-World Safety Profile of Adjuvant Abemaciclib in HR+/HER2− Early Breast Cancer

Background/Objectives: Treatment with adjuvant abemaciclib plus endocrine therapy (ET) has been demonstrated to improve outcomes in patients with HR+/HER2- early breast cancer at high risk of recurrence. However, real-world data regarding abemaciclib tolerability and treatment ma...

Terminology for describing the 24-h cycle of physical activity, sedentary behaviour, and sleep: a scoping review

Abstract Background Physical activity, sedentary behaviour, and sleep are three behaviours which occupy the 24-h cycle and interact to influence a multitude of health outcomes. Different terms are currently used to describe these behaviours collectively (e.g., movement behaviours...

How ageism shapes gerontogeriatric competencies in newly graduated nurses: A cross-sectional analysis

This cross-sectional study examined the association between ageism and self-perceived gerontogeriatric competence among newly graduated registered nurses (NGRNs). A total of 242 NGRNs completed an online questionnaire that included the Ambivalent Ageism Scale (AAS) and the Geront...

33rd GP2A Annual Medicinal Chemistry Conference, XIVth Paul Ehrlich MedChem Euro-PhD Network Meeting & COST Action One Health Drugs Against Parasitic Vector Borne Diseases in Europe and Beyond (OneHealthdrugs)

The 33rd Annual Conference of the Group for the Promotion of Pharmaceutical Chemistry in Academia (GP2A), held in Nantes from 11 to 13 June 2025, marked a significant expansion of the organization’s scope and collaborative efforts. Building on the success of the previous meeting...

Primary prevention of child sexual abuse with preschool children in Portugal: A pilot feasibility trial of the CARE program

Background Child sexual abuse (CSA) is a major public health concern, yet rigorously evaluated and fully manualized primary prevention programs for preschool children remain scarce. Evidence on the feasibility and acceptability of such interventions among young children and their...

Where the Self Places Conflict: Reality Resistance, Organism–Environment Coupling, and Conditional Return

This paper introduces a VIVENS state-space-inspired research framework for studying conflict as a bidirectionally coupled organism–environment process. The framework distinguishes reality resistance—the mismatch between an expected, desired, defended, or identity-compatible organ...

Characterization and treatment of polymicrobial biofilms in prosthetic joint infections

Abstract Prosthetic joint infections are complex and associated with high economic and social costs. Polymicrobial cases remain poorly understood, particularly regarding bacterial interactions and antibiotic response within mixed-species biofilms. We introduce two approaches for...

Cross-Cultural Validation and Psychometric Evaluation of the Birth Beliefs Scale Among Portuguese Pregnant Women

BACKGROUND: Beliefs about childbirth shape women's expectations, decisions, and experiences. Although several tools assess related constructs such as fear or self-efficacy, few instruments focus specifically on childbirth beliefs. The Birth Beliefs Scale (BBS) addresses this gap...

High-PerformingVacuum-Pressure Swing Adsorption Unitfor Drying Hydrogen from Water Electrolysis

Abstract The growing demand for ultrapure hydrogen in fuel cell applications requires the development of efficient and cost-effective purification technologies. This study reports the development, optimization, and techno-economic assessment of a vacuum-pressure swing adsorption...

Lightweight Llama Models with Experts’ Curated RAG for Electrical Engineering Education: An Exploratory Comparison

This study investigates the benefits of expanding small and open Large Language Models (Llama 3.x family) with retrieval and explicit referencing (retrieval-augmented generation), configured to refuse to respond when unsure about the answer. Additionally, we compare this augmente...

Where the Self Places Conflict: Reality Resistance, Organism–Environment Coupling, and Conditional Return

This paper introduces a VIVENS state-space-inspired research framework for studying conflict as a bidirectionally coupled organism–environment process. The framework distinguishes reality resistance—the mismatch between an expected, desired, defended, or identity-compatible organ...

Data-driven identification of modifiable risk factors for colorectal cancer in Palestine using machine learning methods

Colorectal cancer (CRC) is a growing public health concern in Palestine, yet limited evidence is available on locally relevant behavioral, dietary, socioeconomic, and contextual predictors. Machine learning (ML) may support prevention-oriented risk stratification by identifying c...

Conformal principal-asymptotic nets: Parametric design and modular construction of elastic gridshells

Current modular design approaches often rely on numerical optimization to satisfy fabrication constraints, which can be computationally intensive and sensitive to initial geometric conditions. This work introduces a parametric design algorithm based on Conformal Principal-Asympto...

Catalytic Ozonation of Environmentally Relevant Pharmaceuticals Using Oxygen- and Nitrogen-Doped Activated Carbons

Catalytic ozonation is one of the advanced oxidation processes (AOPs) that have yielded promising results in the treatment of emerging pollutants, in which the catalyst plays a fundamental role. In this study, surface oxygen and nitrogen groups were introduced onto two commercial...

Telephone versus in-person administration of the Early Childhood Development Index 2030: a crossover study, Brazil, Canada, India and Malawi.

Objective: To examine agreement between telephone and in-person administration of the Early Childhood Development Index 2030 (ECDI2030) survey. Methods: -tests and intraclass correlation coefficients. Findings: : -0.36), regardless of modality. However, pooled and stratified intr...