Universidade do Porto

Orthopaedic Management of Bone Metastases from Lung Cancer

Background/Objectives: Bone metastases from lung cancer can cause pain, pathological fracture, spinal instability, metastatic spinal cord compression and loss of independence. Lung cancer-specific evidence for orthopaedically relevant local management remains fragmented. This rev...

Measurement of Tuberculosis treatment adherence: A methodological scoping review of observational studies

Despite extensive conceptual development, the definition and measurement of Tuberculosis (TB) treatment adherence remain inconsistent. This ambiguity obscures what is being assessed and compared across studies. This scoping review examined how adherence is labelled, defined, and...

Severe Pediatric Ocular Surface Disease: Multimodal Approach and Treatment

Background/Objectives: Pediatric ocular surface disease associated with ocular rosacea, chronic blepharitis and meibomian gland dysfunction may result in significant corneal morbidity. In refractory cases, the limitations of conventional therapy have stimulated interest in adjunc...

Characterisation of lithium-bearing minerals for dense media separation

Lithium-bearing minerals from a tantalite processing plant in Minas Gerais, Brazil, with a head grade of 1.06% Li 2 O, were characterised to evaluate the potential of dense medium separation for spodumene pre-concentration in the −850/+500 μm size fraction, selected to evaluate t...

Breeding bird data from the Côa River Basin (Portugal): twenty-six years of change in a Mediterranean landscape in transition

Breeding bird data from the Côa River Basin (Portugal): twenty-six years of change in a Mediterranean landscape in transition This data package brings together standardized breeding-bird transect data collected in the Côa River Basin, north-eastern Portugal, over twenty-six years...

Does governance shape local financial condition? Evidence from Brazilian municipalities

IMPACTUsing a national panel of all 5,570 Brazilian municipalities from 2018 to 2023, this study finds that stronger managerial governance, measured through planning capacity, staffing structure, and transparency, is associated with more favourable fiscal profiles across three di...

Influence of Continuous Chelation on Root Dentin: A Laboratory Study

Background/Objectives: Continuous chelation has emerged as an alternative to conventional sequential irrigation by combining sodium hypochlorite (NaOCl) with weak chelators in a single irrigant solution. This study evaluated and compared the effects of different final irrigation...

Pedagogical Interventions That Support Self-Regulated Learning in Secondary School Students: A Systematic Literature Review

Self-regulation of learning (SRL) is a key skill for secondary school students, placing them as active and conscious agents of their own learning. It enables learners to plan, monitor, and evaluate their progress, fostering autonomy and responsibility. Teachers play a crucial rol...

Beyond Modified Transudates: Diagnostic Performance of the Feline Infectious Peritonitis Effusion Index on the Sysmex XN-1000V

The antemortem clinical and clinicopathological diagnosis of feline infectious peritonitis (FIP) remains challenging, particularly when effusions deviate from the classically protein-rich, low-to-moderate-cellularity phenotype. The FIP Effusion Index, defined as the ratio of delt...

The Canine Leishmaniosis Proteinogram: A Reference Serum Electrophoretic Atlas of 5544 Dogs over 18 Years

Serum protein capillary electrophoresis can characterise dysproteinaemia in dogs tested for canine leishmaniosis (CanL) as an integrated clinicopathological phenotype of humoral immune activation. This retrospective laboratory-based study evaluated serum protein electrophoretic p...

High-Performing Unitized Regenerative Fuel Cell Using PGM-Free Bifunctional Catalysts from Waste-Derived Carbon

Abstract Unitized regenerative alkaline-exchange membrane fuel cells (UR-AEMFCs) are a promising technology for energy storage, attending to their ability to operate in both galvanic (FC) and electrolytic (WE) modes. However, their round-trip efficiency (RTE) is greatly dependent...

Energetic constraints reshape climate-tracking opportunities for large mammals across European protected-area networks

Study overview Protected areas (PAs) remain central to biodiversity conservation, but climate change is shifting temperature conditions beyond the boundaries of many protected sites. Their effectiveness therefore increasingly depends on both the time for which analogous climatic...

Energetic constraints reshape climate-tracking opportunities for large mammals across European protected-area networks

Study overview Protected areas (PAs) remain central to biodiversity conservation, but climate change is shifting temperature conditions beyond the boundaries of many protected sites. Their effectiveness therefore increasingly depends on both the time for which analogous climatic...

Sex and Mortality Among Patients with Papillary Thyroid Cancer

Importance Unlike patient age, which has been a well-established and routinely used primary biological prognostic factor in the risk stratification of papillary thyroid cancer (PTC), the prognostic value of patient sex remains controversial in this common endocrine malignant neop...

Hope-Oriented Care in Palliative Care: Relational and Organizational Perspectives From Nurses

Objectives Hope is a dynamic, relational dimension of palliative care; little is known about how nurses themselves perceive and navigate hope-oriented practice. This study aimed to explore experienced palliative care nurses’ perceptions of the relational and organizational barrie...

Chaperone-inspired nanobodies enable pathway-selective control of Tau self-assembly

Abstract Selective control of pathogenic protein self-assembly remains a major challenge for intrinsically disordered amyloid-forming proteins such as Tau. Here we show that nanobodies originally raised against the chaperone S100B unexpectedly cross-react with Tau as potential pa...

Environmental DNA for detecting marine fish species: testing the volume of sampled water, markers and primers in a public oceanarium

To maximize the efficiency of marine fish detection using environmental DNA (eDNA) metabarcoding, methodological factors such as PCR amplification bias and sampled water volume must be carefully considered. In this study, we evaluated the influence of different genetic markers (C...

Microplastic-mediated transfer of parabens and its ecotoxicological impact on Chlorella vulgaris

Microplastics (MPs) are pervasive contaminants in aquatic systems and wastewater (WW), with polystyrene microplastics (PS-MPs) posing remarkable ecotoxicological risks and acting as potential carriers for other emerging contaminants (ECs), such as parabens - widely used preservat...

Examining Diagnostic Criteria for Atypical Anorexia Nervosa Post Metabolic Bariatric Surgery

ABSTRACT Objective To examine the applicability of current diagnostic criteria for atypical anorexia nervosa (AAN) to patients 1 year post Metabolic Bariatric Surgery (MBS). Method This prospective ongoing cohort study included patients from the multicenter Psychosocial Registry...

Portugal's health in all policies: A comprehensive review of legal frameworks

Introduction Health inequalities persist across Europe, highlighting the need for cross-sectoral strategies like Health in All Policies (HiAP). However, approaches to health and social policy vary across countries, implementation is difficult, and further evaluations are needed t...