Universidade de São Paulo

Western amazon 2020 extreme heatwave

Abstract Between September and November 2020, an extreme climate event characterized by the co-occurrence of severe drought, extreme heat stress, widespread burning, and respiratory health impacts affected southwestern Amazonia. This study investigated the event using an integrat...

Metropolis and kinetic Monte Carlo methods for studying protein interactions

Abstract Protein–protein interactions are stochastic and play a central role in determining the structural and dynamic properties of biological systems. Computational approaches that account for the probabilistic nature of these interactions are therefore essential for understand...

Multifunctional NaNbO3: Photocatalytic Degradation of Methylene Blue and Intrinsic Antimicrobial Activity against Enterococcus faecalis and Candida albicans

Abstract In this paper, sodium niobate (NaNbO3) was synthesized by the microwave-assisted hydrothermal method at 150 °C for 70 min, followed by calcination at 550 °C for 2 h. X-ray diffraction revealed the coexistence of orthorhombic P21ma and Pbma phases, while scanning electron...

Role of aerobic exercise training on myocardial infarction induced-cardiac dysfunction, dysautonomia and oxidative stress in female ob/ob mice.

We investigated the effects of aerobic exercise training (ET) on cardiac function, autonomic modulation, and inflammatory and oxidative stress markers in an experimental model of diabetes and obesity underwent myocardial infarction (MI). Female ob/ob mice were randomized into: sh...

Temporal assessment of N-cycling genes and nutrient-acquiring enzymes under rotational grazing

Despite the importance of microbial activity for the sustainability of grazing systems, longitudinal assessments of microbial responses to grazing remain scarce. We monitored functional N-cycling genes and C-, N-, and P-acquiring extracellular enzyme activities across two contras...

Upcycling pharmaceutical capsules into porous activated carbon and activated carbon ash for efficient emerging contaminant removal

The management of pharmaceutical waste remains a significant challenge and presents opportunities for the development of value-added materials. In this study, discarded pharmaceutical gelatin capsules were converted into activated carbons and Ti-rich inorganic residues through se...

Proteomic profile of the dentine pellicle modified with plant polyphenols and fluoride

Abstract Objectives Despite its protective role, the dentine pellicle has rarely been studied, therefore we aimed to map out the proteomic profile of in vitro dentine pellicles before and after modification. Materials and methods A total of 135 human dentine specimens were prepar...

Factors affecting patient safety in teleconsultations for health services: a scoping review protocol.

OBJECTIVE: This review will map the factors affecting patient safety in teleconsultations for health care services. INTRODUCTION: The use of communication technologies has gained prominence in the new paradigm of health care delivery. However, despite this expansion, patient safe...

Electrophysiological properties of the dorsal motor nucleus of the vagus motoneurones controlling airway mucus secretion in rats

Abstract The parasympathetic efferent innervation to the respiratory airways controls bronchoconstriction and mucus secretion. It is known that the parasympathetic respiratory motoneurones (PRMNs) projecting to the airways are located in the nucleus ambiguus (NA) and dorsal motor...

Beyond Tumor-Intrinsic STAT3: Integrating Metabolic and Immune Communication in the Tumor Microenvironment of Cervical, Ovarian, and Endometrial Cancers

Cervical, ovarian, and endometrial cancers comprise biologically distinct malignancies with substantial heterogeneity in their molecular alterations, metabolic dependencies, immune landscapes, and therapeutic responses. Despite advances in surgery, chemotherapy, radiotherapy, tar...

Cross-Sectional Validation of the NUTRISCORE Screening Tool in Outpatient Oncology Patients

BACKGROUND AND OBJECTIVE: Malnutrition in cancer patients is a complex and multifactorial condition. Validated nutritional screening instruments are essential to ensure diagnostic, accuracy and guide effective nutritional interventions. This study aimed to validate the NUTRISCORE...

Green Hydrogen in Brazilian Media: Dominant Narratives and Missing Dimensions of the Energy Trilemma

ABSTRACT Media discourses help shape the visibility and legitimacy of energy transition pathways in the public sphere. This study examines how Brazilian mainstream newspapers framed green hydrogen and assesses the alignment of these narratives with the energy trilemma: energy sec...

Short-term carbon stabilization in earthworm casts under tropical agricultural system

Earthworm casts are recognized as microsites that influence soil organic carbon (SOC) dynamics, yet their stabilization mechanisms in highly weathered tropical soils remain unclear. We investigated organo - mineral interactions in casts from anecic Rhinodrilidae earthworms in a H...

Unveiling the effects of tautomerism, pH, and solvation on the UV/Vis spectrum of sulfapyridine: a joint theoretical and experimental study

Abstract Context Sulfapyridine (SPY) is a sulfonamide frequently detected as contaminant in aquatic environments, largely due to incomplete metabolism and its extensive use in livestock production and other anthropogenic activities. The spectroscopic properties of SPY are strongl...

Age-related variation in heart rate variability across receptor-defined breast cancer groups, with distinct patterns in triple-negative disease: a cross-sectional study

Breast cancer (BC) is the most common malignancy among women worldwide, and growing evidence suggests that autonomic nervous system (ANS) activity modulates tumor biology and the tumor microenvironment. Heart rate variability (HRV), a non-invasive index of ANS balance, is influen...

Effect of air-borne particle abrasion and tribochemical silica coating on surface characteristics, mechanical behavior, and bonding performance of 3D-printed resin-based materials

Abstract Objectives This study evaluated how air-abrasion material, application time, and aging affect the surface characteristics, mechanical behavior, and bonding performance of three-dimensionally (3D) printed resin. Methods Specimens were treated with aluminum oxide (Al₂O₃) o...

The integration of social determinants of health in antenatal care policies in Brazil: a content analysis of five federal documents

Background Inequities shaped by the Social Determinants of Health (SDH) and intersecting forms of discrimination such as race, age, and socioeconomic status critically influence access to and quality of antenatal care (ANC), a key intervention for preventing maternal mortality. B...

A systematic review and individual patient data meta-analysis to determine the effect of primaquine dose on efficacy, tolerability and safety in uncomplicated Plasmodium vivax malaria in Latin America

Background Primaquine is widely used to prevent relapses of Plasmodium vivax malaria, but the optimal dose in Latin America is unknown. We undertook a systematic review and individual patient data meta-analysis to investigate the efficacy, tolerability and safety of different pri...

Chronic ethanol ingestion induces morphological alterations in the uterine horn mucosa of Calomys callosus

Abstract The present work was carried out to evaluate the possible effects of chronic alcohol intake on the histology and ultrastructure of the endometrial lining epithelium of the uterine horn of Calomys callosus . Twenty adult female rodents, Calomys callosus , three months old...

Non-thermal plasma engineering of CuO/Cu2O nanostructures on copper mesh for tunable selectivity in electrochemical CO2 reduction

Abstract The rising levels of atmospheric CO₂ have exceeded the capacity of the natural carbon cycle, driving interest in electrocatalytic CO₂ reduction as an environmental and energy solution. Copper-based tandem electrocatalysts remain the most investigated catalysts due to the...