Universidade de São Paulo

Unveiling Float Glass Staining Induced by an Acid‐Cleaning Product

ABSTRACT Staining of glass facades is a recurring and significant problem worldwide. This study investigates the causes of staining observed on six laminated float glass samples from four manufacturers (α, β, γ, and δ). Samples from β, γ, and δ were new, whereas those from α (α 1...

Clinical and Economic Burden of Complicated Pneumonia and Invasive Disease due to Streptococcus pneumoniae Serotype 19A in an Ecuadorian Pediatric Reference Hospital

Serotype 19A has emerged as an important cause of pneumococcal disease following the introduction of the 10-valent pneumococcal conjugate vaccine (PCV10). In this retrospective study of children hospitalized with culture-confirmed invasive pneumococcal disease at an Ecuadorian pe...

The World Psychiatric Association (WPA) Guideline on Schizophrenia Spectrum Disorders Management for Low- and Middle-Income Countries

There is a pressing need to address the unique challenges of managing Schizophrenia Spectrum Disorders (SSD) in Low- and Middle-Income Countries (LMICs), where mental health resources are scarce and unevenly distributed. To develop this evidence-based guideline, we conducted a sy...

The use of biologic adjuncts in tooth autotransplantation: a scoping review

PURPOSE: To summarize the available clinical evidence on biological adjuncts in tooth autotransplantation, including adjunct types, application protocols, procedural variables, reported outcomes, and evidence gaps. METHODS: This scoping review followed JBI guidance and PRISMA-ScR...

Impact of GLP-1 and GLP-1/GIP receptor agonists before, during, and after pregnancy: a narrative review

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) receptor agonists (GLP-1RA and GIP-RA) are a class of medications that mimic the endogenous effects of GLP-1 and have gained increasing attention due to their substantial clinical potential. Origin...

Detection of Leishmania infantum DNA in Sand Flies and Assessment of Zoonotic Transmission Risk in Central Honduras: A One Health Approach

Integrated One Health studies are essential for assessing the risks of leishmaniasis transmission. In Honduras, the most prevalent clinical presentation of leishmaniasis is the non-ulcerated cutaneous form caused by Leishmania infantum; however, research on its transmission dynam...

Relationship Between Nursing Diagnoses, Mortality and Length of Stay in the ICU: A Retrospective Cohort Study

ABSTRACT Background Nursing process is a systematic, problem‐solving framework structuring clinical reasoning and patient‐centred care; within it, Nursing Diagnoses (ND) link clinical assessment to planning and implementing individualised interventions. However, evidence demonstr...

Lytic activity of F8-like phage φSPM-1 against One Health lineages of carbapenem-resistant Pseudomonas aeruginosa

Abstract The increasing resistance of Pseudomonas aeruginosa to carbapenem antibiotics is shifting the landscape of high-risk clones from a strictly hospital-acquired threat to a global pathogen with One Health relevance. Given the limited therapeutic options available, developin...

Social cues on stone tools outweigh raw material properties in wild primates

1. Abstract The ability to select appropriate tool material enabled early hominins access to new resources and environments. The underlying mechanisms driving tool selection effectively remain unknown. Observations of extant primates have demonstrated strong selectivity for speci...

Two new species of Diadiplosis (Diptera: Cecidomyiidae), predators of mealybug (Hemiptera: Pseudococcidae) from Brazil

Abstract Predatory cecidomyiids of the genus Diadiplosis Felt, 1911 (Diptera: Cecidomyiidae) are widely distributed throughout the Neotropical Region. Of the 34 species currently known in the genus, 14 have been recorded from Central and South America, making it, thus far, the ge...

Impacto econômico da implementação de um protocolo institucional de analgossedação em uma Unidade de Terapia Intensiva Neonatal

Introdução: A analgossedação adequada é imprescindível no manejo de pacientes críticos em Unidades de Terapia Intensiva Neonatais (UTIN). Contudo, o manejo criterioso de fármacos é crucial para evitar tanto a submedicação quanto os desfechos adversos associados ao excesso terapêu...

ORBITA: Organelle-Based Integration of Translocation and Adaptation in Cancer

Cancer is currently understood as a disease of dynamic adaptation, in which tumor cells continuously reprogram their metabolism and signaling networks to survive adverse conditions such as oxidative stress and exposure to chemotherapeutic agents. Although these processes have bee...

Platelets as regulators of cancer immunity: mechanisms and therapeutic perspectives

Abstract Platelets correspond to one of the most abundant components of the blood and shape the tumor microenvironment, modulate antitumor immune responses, and influence clinical outcomes in cancer patients. Recent studies have expanded our understanding of the mechanisms underl...

Educational Value of a Leadership-Focused High-Fidelity Simulation Scenario in Undergraduate Nursing Education: A Single-Group Educational Intervention Study

Aim/Objective: To evaluate undergraduate nursing students’ perceptions of the educational design, debriefing quality, satisfaction, and self-confidence associated with a leadership-focused high-fidelity simulation scenario involving the management of a sharps-injury event. Backgr...

Investigating changes in the blood-brain barrier in schizophrenia spectrum disorders: design and methodology of a longitudinal dynamic contrast-enhanced MRI study

Schizophrenia spectrum disorders (SSDs) are clinically and biologically heterogeneous and lack reliable biomarkers for stratification, treatment response and course prediction. Evidence from postmortem, fluid biomarker, and neuroimaging studies suggests that changes in the blood-...

Contribution of One‐Electron Oxidation of Purine and Pyrimidine Bases to the Photo‐ and Radiation‐Induced Damage to Cellular DNA

One‐electron oxidants that include type I photosensitizers, biologically relevant carbonate anion radical generators, and high intensity UVC nanosecond lasers are able to ionize in aqueous solution purine and pyrimidine nucleobases. The survey is aimed at critically reviewing the...

Executive Compensation Structure and Eco‐Innovation: Evidence From Brazilian Listed Companies

ABSTRACT Drawing on agency theory, this study investigates the relationship between executive compensation structure and environmental innovation, focusing on fixed, short‐term, and long‐term compensation components. The analysis is based on a panel of 111 non‐financial firms lis...

A Low-Cost Digital Twin Framework for Sustainable Manufacturing Education Integrating SAP, Node-RED, and AI-Based Decision Support

The excessive cost and complexity of Industry 4.0 laboratory infrastructure limit the adoption of Digital Twin concepts in engineering education. This paper proposes a low-cost Digital Twin framework for sustainable manufacturing education integrating SAP NetWeaver, Node-RED, and...

Effects of photobiomodulation, alone or combined with dexamethasone, on cellular metabolic activity and inflammatory markers in LPS/IFN-γ-stimulated J774 macrophages

The aim of the present study was to investigate the effects of photobiomodulation (PBM), dexamethasone (DEXA), and their combination on cellular metabolic activity and inflammatory cytokines in LPS/IFN-γ-stimulated J774 macrophages.Cells were stimulated with lipopolysaccharide (L...

Reduced Food Availability Amplifies Behavioral Depression and Impairs Locomotor Performance After Immune Challenge in Xenopus laevis

Mounting an immune response and locomotor activity are energetically costly processes that can generate trade-offs affecting energy allocation, muscle performance, and activity patterns. The balance between these demands can be modulated by factors such as food availability and e...