Purdue University West Lafayette

AI and the Decentering of Disciplinary Creativity

Abstract This paper examines the role of artificial intelligence in scientific problem-solving, with a focus on its implications for disciplinary creativity. Drawing on recent work in the philosophy of creativity, I distinguish between creative approaches and creative products, a...

Behavior and Design of Bolted Splice Connections for C-PSW/CF Walls

Abstract This paper briefly summarizes the results from experimental and numerical investigations conducted on full-scale planar concrete-filled composite plate shear walls (C-PSW/CF) with bolted splice connections. These experimental results and numerical models are used to deve...

Manganese transport, homeostasis, and neurotoxicity

Manganese (Mn) is an essential metal required for many physiological functions, and deficiency or over-exposure is associated with neurological dysfunction and neuropathology. Tight homeostatic control of Mn in the body is required to maintain optimal physiological levels and pro...

An Approach for Testing of Embedded Interconnects that Bypasses the Interconnect Isolation Logic

In a chiplet-based design, logic blocks (chiplets) are connected by a large number of interconnects to form larger functions. The interconnects require comprehensive testing to ensure that the design operates correctly. The interconnects are tested using isolation logic to suppor...

A Reproducible Evidence-Audit Framework for Leakage, Feature Stability, and Transportability in Translational Omics Classification

Submission-aligned code, outputs, figures, supplements, and manuscript for a reproducible evidence-audit framework in high-dimensional translational omics classification. A naive global-selection workflow is contrasted descriptively with a guarded nested workflow; because the arm...

Temporal profiling of hippocampal astrocyte reactivity reveals persistent GFAP cleavage and complement C3 association after status epilepticus

Astrocytes play essential roles in maintaining brain homeostasis, regulating synaptic transmission, supporting neuronal metabolism, and preserving blood-brain barrier integrity. Following prolonged seizures, such as status epilepticus (SE), astrocytes undergo structural and molec...

AI failures in the eyes of the downstream developer: a first look at concerns, practices, and challenges

Abstract With the advancement of AI models, more software systems are adopting AI as a component to facilitate automation. Pre-trained models (PTMs) have become a cornerstone of AI-based software, allowing for rapid integration and development with lower training cost. However, t...

A Reproducible Evidence-Audit Framework for Leakage, Feature Stability, and Transportability in Translational Omics Classification

Submission-aligned code, outputs, figures, supplements, and manuscript for a reproducible evidence-audit framework in high-dimensional translational omics classification. A naive global-selection workflow is contrasted descriptively with a guarded nested workflow; because the arm...

Presenceof CriticalMaterials in Select U.S. MunicipalSolid Waste Landfill Leachates

Abstract This study detected and quantified a broad array of critical materials and other elements in U.S. municipal solid waste (MSW) landfill leachates in both the aqueous (i.e., supernatant) and wet solid fractions. A total of 59 elements were measured in 37 landfill leachate...

Considerations for Ammonia-fuelled Aircraft and Propulsion Systems: A Component-level and System Analysis

Abstract Alternative fuels for aviation as substitutes for Jet-A are currently being investigated globally. Ammonia has emerged as a potential candidate given its robust supply chain, technological maturity, and global infrastructure. Ammonia combustion at scale has been successf...

Wake-Up Call from the Past Investments

Asset impairment accounting requires firms to reassess their existing assets-in-place, namely, the outcomes of past investments, which enriches the information environment within the firm. We investigate whether this reassessment influences corporate investment strategies for lon...

Biracial Emerging Adults’ Phenotype and Multiracial Pride Predicting Academic Achievement via Discrimination Experiences

The current study examined how Biracial emerging adults’ phenotype and Multiracial pride were associated with racial discrimination and, in turn, GPA. Participants were 378 Biracial emerging adults. Results indicated that there were gender differences. Among women, Multiracial pr...

Computational modeling of motor-driven extension of microtubule bundles in axons reveals a biphasic effect of crosslinker density

In addition to actin assembly at the growth cone, neuronal axons elongate via interactions between microtubules, dynein motor proteins and cross-linking proteins. Dynein translocates microtubules toward the growth cone and exerts extensile forces for axonal outgrowth. During this...

Fail-Slow Hardware Failure Bug Analysis and Detection for Cloud Systems

Fail-slow hardwares are still running and functional, but in a degraded mode, thus slower than their expected performance. Bugs triggered by fail-slow hardwares cause severe cloud system failures. Existing testing tools fail to efficiently detect these bugs due to overlooking the...

Currency transition: the use of foreign coins and ‘dollarization’ in seventeenth-century Ottoman Istanbul

This article investigates the seventeenth-century Ottoman Empire’s transition from domestic to foreign currency, a striking episode in early modern monetary history. Drawing on over 22,000 Istanbul court records, we provide the first large-scale quantitative account of how Europe...

Does Sensitivity to Positive and Negative Environmental Cues Relate to Body Image?

Higher reward responsiveness and behavioral inhibition are linked to eating disorders, and thus, may also be connected to body image. In the current study, we considered how both reward responsiveness and behavioral inhibition relate to body image. Undergraduates (N = 155; 67.7%...

Genetics of growth resilience- and uniformity-related indicators derived from sparse body weight data in Angus–Brangus cattle under (sub)tropical conditions

Abstract Background Resilience is an important breeding objective in livestock, reflecting the capacity of animals to maintain their performance or recover quickly from short-term environmental perturbations. The derivation of resilience indicators requires longitudinal measureme...