Princeton University

Coreless exoplanets induced by metal–silicate miscibility

The rocky interiors of exoplanets are generally expected to differentiate into a silicate mantle and a metallic core due to the immiscibility of metal and silicate under typical planetary formation conditions. Here, we use large-scale molecular dynamics simulations driven by mach...

Plasmon-Driven ChargeTransfer Aids Selective NonthermalVibrational Excitation in Nitrobenzenethiol on Silver Nanoparticles:Insights from Embedded Correlated Wavefunction Calculations

Abstract In plasmonic photocatalysis, a commonly invoked reaction enhancement mechanism is the excitation of a metal-to-molecule charge transfer state, resulting in transient-ion formation. Once accessed, a transient-ion state leads to changes in the molecular geometry that can l...

Odorant receptor coexpression and multi-expression in the dengue mosquito

Drosophila olfactory sensory neurons tend to express a single ligand-specific receptor, following a one-receptor-per-neuron rule expected to apply broadly across insects. Recent work challenges this view by showing that some neurons in the mosquito Aedes aegypti coexpress multipl...

Atmospheric turbulence sensing with structured terahertz beams containing orbital angular momentum

Clear-air turbulence poses a persistent hazard to aviation, yet it evades conventional weather radar and remains difficult to detect. Existing optical sensing methods falter under severe turbulence and are extremely vulnerable to misalignment between airborne nodes. Here we intro...

Fast, unconditional reset and leakage reduction in fixed-frequency transmon qubits

Abstract On-demand qubit-state initialization is a prerequisite for quantum computation. We demonstrate such a protocol in a device consisting of fixed-frequency transmon qubits pair-wise coupled via tunable couplers — an architecture that is also compatible with the surface code...

Drought dynamics explain once in a century yellow fever virus outbreak in Brazil with implications for climate change

While excess rainfall is associated with mosquito-borne disease because it supports mosquito breeding, drought may also counterintuitively increase disease transmission by altering mosquito and host behavior. This phenomenon is important to understand because climate change is pr...

Persistent Free Volume Governs (Anti)plasticization in Chitosan-Water Mixtures

Abstract Chitosan is a highly versatile and sustainable polymer with a broad range of potential biological and materials engineering applications. Despite its versatility, the native brittleness of chitosan limits its broader utilization. This limitation can be addressed by blend...

Eco-evolutionary feedback reshapes competitive dynamics in an orchard fly system

The feedback between competition and evolution is central to hypotheses about the origin and maintenance of species diversity. Yet, whether competition-induced evolution is sufficiently rapid, consistent, and strong to maintain diversity on ecological timescales remains unresolve...

High-resolution simulation and modeling of tropical-cyclone induced power outages in the United States

Storm driven power outages impose large and uneven costs on communities, yet operational outage prediction models remain constrained by available datasets. Existing approaches either provide high resolution forecasts for a small number of utilities with internal outage records, o...

Characterizationof Dapalides D and E and GenomicComparison of the Two Co-Occurring Dapalide-Producing Dapis spp.

Abstract Marine cyanobacteria are a rich source of diverse bioactive natural products, targeting proteins involved in many diseases. Here, we combined metagenomic analysis to enhance the structure elucidation process of two new cyclodepsipeptides named dapalides D (1) and E (2) f...

AI and the Decentering of Disciplinary Creativity

Abstract This paper examines the role of artificial intelligence in scientific problem-solving, with a focus on its implications for disciplinary creativity. Drawing on recent work in the philosophy of creativity, I distinguish between creative approaches and creative products, a...

Economic Conditions and Incarceration in the United States: Evidence from Missouri, 1850–1930

This paper investigates the relationship between economic conditions and incarceration in the postbellum United States. Leveraging unique administrative prison records in Missouri from 1850 to 1931 and the differential exposure to national agricultural price changes across counti...

Cognitive reappraisal changes cognitive evaluations of images more strongly than affective reactions

Abstract Cognitive reappraisal is an emotion regulation strategy that involves changing one’s interpretation of a situation to change its emotional impact. Cognitive reappraisal studies typically assess changes in valence ratings following reappraisal as the primary dependent var...

Bridging the social license gap: How community-directed communication shapes risk perception and acceptance of carbon capture and storage in the United States

Achieving global climate targets demands rapid deployment of new technologies, yet technological readiness risks outpacing the social license needed for deployment. Carbon capture and storage (CCS) exemplifies this challenge: deployment is expanding rapidly, but public awareness...

A compendium of next-generation patient-derived models for diverse cancers

Abstract The development of new therapeutics and the validation of pathogenetic cancer mechanisms require representative laboratory models 1,2 . However, existing collections represent only a fraction of the diversity observed in human cancer 2–4 . Recent technologies have enable...

Evaluating Mechanical-EmbeddingML/MM for PredictingMutation Effects in Chorismate Mutase Catalysis

Abstract Predicting how mutations alter enzyme catalysis remains a central challenge in enzymology and enzyme engineering. Although quantum mechanics/molecular mechanics (QM/MM) simulations can in principle compute the activation free energy associated with enzymatic reactions, t...

Linker Symmetry Lowering as a Strategy to Tune Electronic Properties in Two‐Dimensional Conductive MOFs

ABSTRACT Two‐dimensional conductive metal–organic frameworks (2D cMOFs) have largely relied on highly symmetric linkers that give rise to symmetry‐protected electronic degeneracies. Although such symmetry usually promotes extended conjugation and often leads to high electrical co...

Dynamics, function, and regulation of mammary stem cells in development and disease

Understanding the heterogeneity of mammary epithelial cells and their contributions to postnatal development and regeneration is of great importance. Recent advances have defined the intrinsic complexity of the mammary epithelium, its stromal interactions, and the ontogeny of adu...

What Does It Mean to Be Black? Experimental Evidence on the Situational Deployment of Racial Schemas

How do Black Americans construct narratives about the meaning and boundaries of Blackness in America today? We leverage an original, nationally representative survey experiment among U.S.-born Black Americans ( n = 3,100) to examine (1) justifications used to validate or reject a...

Structural insights into xyloglucan recognition by an ABC transporter from a Gram‐positive, thermophilic bacterium

Xyloglucan (an α‐1,6‐xylosyl–substituted β‐1,4‐glucan) is a major hemicellulose of the primary cell wall of many plants and an important growth substrate for biomass‐degrading bacteria in diverse ecological niches, including the gut microbiome and hot springs. In Gram‐positive ba...