Princeton University

Autonomous Folding of Soft Matter From Living Polymers

ABSTRACT Origami provides a versatile framework for shape‐morphing, yet existing systems are limited to transitions between an initial state and a predetermined folding outcome, offering little tunability after fabrication. Here we introduce a dynamic “living” polymer that contin...

Effects of ketone supplementation on metabolic and hormonal profiles in polycystic ovary syndrome

Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by metabolic dysfunction, hyperandrogenism, and reproductive hormone imbalance. This meta-analysis aimed to evaluate the effects of ketone supplementation on anthropometric, metabolic, and h...

Technologies of Transition: Pottery Production and Specialization in Early Rome and Its Neighbors. Neutron Activation Analysis of Regional Assemblages and a Mineralogical‐Petrographic Study of Impasto Chiaro‐Sabbioso

ABSTRACT The following paper investigates ceramic production and signs of specialization in Rome and the wider region during the early first millennium bce , through an archaeometric approach using Instrumental Neutron Activation Analysis (NAA), and complementary techniques. A to...

Differentially Private Hierarchical Spectral Clustering

We study hierarchical spectral graph clustering under edge differential privacy (DP) through the lens of iterative eigenvector estimation on adjacency matrices. We propose a differentially private recursive spectral framework, where each binary partition is obtained via a rank-on...

Genomic predisposition is associated with the direction of sex chromosome evolution

Sex chromosome evolution is among the most dynamic genomic innovations in vertebrates, yet why some lineages evolve XY while others evolve ZW remains unclear. Using chromosome-level genomes from 19 geckos, we found that gecko sex chromosomes originated independently from 16 ances...

Mentalizing and heuristics as distinct cognitive strategies in human teaching

Teaching is a foundational social behaviour that can result from mentally effortful reasoning or cognitively frugal heuristics. When do people use these strategies to teach? Here we investigated this using behavioural experiments and computational modelling with adult participant...

Host phylogeny and microbiome composition predict gut nematode community composition within a diverse assemblage of African herbivores

Abstract Gut nematodes influence animal health and fitness, with effects shaped by their abundance and community composition. While closely related host species tend to harbour similar nematodes, the relative roles of host ecology and phylogeny in structuring nematode communities...

Can I Trust You? A Longitudinal Study of the Consequences of Suspicion Among Latina/o Students

Racial/ethnic minority group members vary in the extent to which they are chronically suspicious of the motives behind White people’s positive behavior toward minorities. Chronic suspicion has been shown to shape racial/ethnic minorities’ perception, cognition, emotion, and physi...

Self-rankings as a predictor of scientific impact beyond peer review

Abstract Peer review in academic research aims to ensure factual correctness and identify work of high scientific potential, but rapid submission growth has made this increasingly difficult. Here we investigate an additional measure for identifying high-impact research: authors’...

Mitophagy and Noncoding RNA Regulation in Type 2 Diabetes Mellitus: Molecular Mechanisms, Tissue-Specific Evidence and Translational Perspective

Despite significant therapeutic advances, T2DM remains a global public health challenge that leads to multiple complications, including cardiovascular, renal, hepatic, and neurodegenerative disorders. Mitochondrial dysfunction and impaired mitophagy remain fundamental, yet incomp...

Minimax-Optimal Reward-Agnostic Exploration in Reinforcement Learning

This paper studies reward-agnostic exploration in reinforcement learning (RL)—a scenario where the learner is unaware of the reward functions during the exploration stage—and designs an algorithm that improves over the state of the art. More precisely, consider a finite-horizon i...

Reconstruction of fallout deposition from U.S. atmospheric nuclear tests conducted in New Mexico and Nevada

Abstract Between 1945 and 1962, the United States conducted 101 atmospheric nuclear weapon tests in New Mexico and Nevada, dispersing radioactive fallout across the contiguous United States. We reconstruct the first 10 days of fission-product deposition from the 94 non-zero-yield...

Viscosity of NaAlSi3O8−H2O fluids and implications for arc magmatism

Water plays a crucial role in the transport properties of silicate liquids and is especially important in subduction-zone magma source regions where conditions promote complete miscibility between water and silicate melts. However, accurately tracing the movement of fluids and vo...

Socio-hydrogeology: The past, present, and future of a people-centred and place-based approach to groundwater science

Groundwater systems are shaped by deeply interwoven physical processes and social dynamics, yet traditional hydrogeological approaches have often treated these domains separately. Over the past decade, socio-hydrogeology has emerged in response, offering an approach that systemat...

Little Red Dots host Black Hole Stars: A unified family of gas-reddened AGN revealed by JWST/NIRSpec spectroscopy

Abstract We construct and characterise a sample of 146 little red dots (LRDs) across 2.0 < z < 9.3, selecting all sources with v-shaped UV-optical continua from JWST NIRSpec/PRISM spectra and compact morphologies in NIRCam/F444W imaging. We show that LRD continuum spectra are wel...

Conceptual Shift inOur Understanding of DegenerateRadical Spin Systems: Spin-Rotation Coupling Turned on Its Head

Abstract For most chemists, Kramers’ degeneracy refers to the fact that for any radical system, every potential energy surface is at least doubly degenerate (with spin up and spin down, time-reversed solutions) for all nuclear positions X. Yet, as is well-known to the community o...

Morphogenesis of bacterial colonies in liquid crystalline environments

Natural bacterial habitats are often complex fluids with viscoelastic and anisotropic responses to stress; for example, they can take the form of liquid crystals (LCs), with elongated microscopic constituents that collectively align while still retaining the ability to flow. Howe...

Music evokes shared neural representations of imagined narratives across sensory modalities

The human capacity to construct and share subjective experiences from diverse sensory inputs is central to human cognition, and is vividly exemplified through music listening. Direct, focused music perception has been extensively studied while free, imaginative listening, typical...

Protein LanguageModel Decoys for Target Decoy Competitionin Proteomics: Quality Assessment and Benchmarks

Abstract Large-scale proteomics relies heavily on target–decoy competition for false discovery rate estimation in peptide identification, and the performance of this strategy depends strongly on the design of the decoy database. Classical generators such as reversal and shuffling...

Nanoscale sensing of spatial correlations in nonequilibrium current noise

Abstract Nitrogen-vacancy centers are spatially resolved probes of current noise. So far, current noise sensing with NV centers has primarily been used as a way to probe equilibrium transport coefficients. We develop a framework for computing the spatiotemporal correlations of no...