Peking University

RT-APNN for Solving Gray Radiative Transfer Equations

The Gray Radiative Transfer Equations (GRTEs) are high-dimensional, multi-scale problems that pose significant computational challenges for traditional numerical methods. Current deep learning approaches, including Physics-Informed Neural Networks (PINNs) and Asymptotically Prese...

Accelerated Charge Recombination in MOF Cocrystals Enables Efficient NIR‐Driven Photothermal Polymerization

Understanding charge transfer across donor-acceptor interfaces is essential for designing high-performance optoelectronic materials. Herein, we construct host-guest metal-organic framework (MOF) cocrystals employing a calcium-based naphthalenediimide (NDI) host and electron-rich...

scTransMIL bridges patient-level disease states and single-cell transcriptomics for cancer screening and heterogeneity inference

Single-cell sequencing offers profound insights into tumor complexity. However, reliably linking individual cellular profiles to overall sample-level phenotypes remains computationally challenging, particularly when cell-specific annotations are absent. This disconnect limits the...

Accelerated Charge Recombination in MOF Cocrystals Enables Efficient NIR‐Driven Photothermal Polymerization

ABSTRACT Understanding charge transfer across donor‐acceptor interfaces is essential for designing high‐performance optoelectronic materials. Herein, we construct host‐guest metal‐organic framework (MOF) cocrystals employing a calcium‐based naphthalenediimide (NDI) host and elect...

Bisphenol A and Its Substitutes Bisphenol S/Bisphenol F in Combined Exposure Collectively Exacerbate Hepatotoxicity by Triggering Oxidative Stress and Inflammatory Responses via the PI3K-Akt/NF-κB Axis

Abstract Bisphenol A (BPA) and its substitutes bisphenol S (BPS) and bisphenol F (BPF) are environmental endocrine-disrupting chemicals that frequently co-occur. However, the hepatotoxic effects and underlying mechanisms of their combined exposure remain unclear. This study integ...

Bone aging: a paradigm of multiscale degeneration and targeted rejuvenation

Bone aging is not merely a process of bone mass loss but rather a multi-level, networked degenerative phenomenon spanning molecular, cellular, tissue, and system levels. With the accelerating pace of global population aging, bone degenerative diseases have emerged as a major publ...

Rare event probabilities in random geometric graphs

Abstract We study rare events in spherical and Gaussian random geometric graphs in high dimensions. In these models, the vertices correspond to points sampled uniformly at random on the d -dimensional unit sphere or correspond to d -dimensional standard Gaussian vectors, and edge...

Perioperative non-invasive neuromodulation for delirium and cognitive recovery: from preclinical evidence to clinical translation

Perioperative neurocognitive disorders (PND) are a challenge for patients to accelerate postoperative recovery, and exploring more effective interventions can help reduce long-term cognitive dysfunction. Non-invasive neuromodulation (NIN) has shown potential in improving postoper...

Impurity-Preserved Density Matrix Embedding Theory for Local Electronic Excitations

Abstract Density matrix embedding theory (DMET), which is usually based on a Schmidt decomposition of Slater determinants by partitioning the full system into impurity and environment in terms of local orthogonal orbitals (LOs), has demonstrated considerable promise in electronic...

Decoding the Biological Function of Bile Acids for Drug Discovery

Conspectus Bile acids are a class of cholesterol-derived metabolites that have long been recognized for their essential roles in dietary lipid absorption and cholesterol homeostasis. Over the past two decades, however, bile acids have emerged as crucial signaling molecules that r...

Redistribution of CD73 Expression on CD4+T Subpopulations in Systemic Lupus Erythematosus and Its Association With Disease Activity

ABSTRACT Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by aberrant immune responses, predominately CD4 + T cells dysfunction. CD73, an ecto‐5′‐nucleotidase mediating adenosine signalling, is essential for immune regulation. Herein, we investigated CD7...

Utilization of Carbon Fiber Spinal Instrumentation in Primary Spinal Tumors: Outcome Analysis from the AO Spine Primary Tumor Research and Outcomes Network

Background The use of carbon fiber-reinforced polyetheretherketone (CFR-PEEK) instrumentation in spinal surgery has emerged as an alternative to traditional titanium-based implants in recent years. This study aims to evaluate the use and performance of carbon fiber instrumentatio...

Pharmacokinetic and safety interactions between aildenafil and clarithromycin, cimetidine, or rifampin in healthy subjects

Aims Aildenafil citrate, an orally bioavailable phosphodiesterase type 5 (PDE5) inhibitor, is primarily metabolized by cytochrome P450 3A4 (CYP3A4). This study aimed to assess potential pharmacokinetic interactions between aildenafil citrate tablets and cytochrome P450 (CYP)3A mo...

A hierarchical neurobiologically inspired control framework for stable and energy efficient locomotion of bionic robotic fish

Balancing behavioral adaptability and actuation stability is crucial for biomimetic autonomous underwater vehicles (AUVs), inspired by fish sensory-motor systems. While biologically inspired computing methods have advanced rhythmic motion generation, it remains challenging to mai...

Exact Chained-Word Threshold and Monotone-Path Structure in the Even Root-of-Unity Kaleidoscope Yang–Baxter Algebra

We prove the chained-word vanishing conjecture of Qiu, Guan, and Yu in the even root-of-unity Kaleidoscope Yang–Baxter representation. For every even N ≥ 4, every complex parameter u with u ≠ 0 and u^N ≠ 1, and every integer exponent tuple, the exact universal vanishing threshold...

Exact Measurement-Dependence Cost across the Noisy GHZ–Mermin Threshold

We determine the exact measurement-dependence cost of faithful local deterministic models reproducing the full outcome table on the even-parity GHZ–Mermin setting set for Pauli X/Y measurements. For every integer n ≥ 3 and isotropic visibility 0 ≤ v ≤ 1, let R = 2^floor((n−1)/2)....

Weight Reduction Heterogenicity and Mediators of GLP ‐ 1RAs and Dual Agonists for Individuals With Obesity: A Meta‐Analysis

ABSTRACT Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and dual agonists have become pivotal options for obesity, but marked weight loss heterogeneity remains poorly understood. This meta‐regression analysis aimed to identify factors influencing this heterogeneity. We sear...

Exact Chained-Word Threshold and Monotone-Path Structure in the Even Root-of-Unity Kaleidoscope Yang–Baxter Algebra

We prove the chained-word vanishing conjecture of Qiu, Guan, and Yu in the even root-of-unity Kaleidoscope Yang–Baxter representation. For every even N ≥ 4, every complex parameter u with u ≠ 0 and u^N ≠ 1, and every integer exponent tuple, the exact universal vanishing threshold...

Reshaping China’s Labour Market: AI’s Dual Impacts on Employee Adaptation and Employer Demand

The rapid advancement of artificial intelligence (AI) is reshaping labour markets globally, with profound implications for China amid structural fragility, youth unemployment and demographic ageing. This study examines AI’s impacts from a dual-perspective framework: employees’ ad...

Exact Measurement-Dependence Cost across the Noisy GHZ–Mermin Threshold

We determine the exact measurement-dependence cost of faithful local deterministic models reproducing the full outcome table on the even-parity GHZ–Mermin setting set for Pauli X/Y measurements. For every integer n ≥ 3 and isotropic visibility 0 ≤ v ≤ 1, let R = 2^floor((n−1)/2)....