National University of Singapore

Next-Generation Water Quality Monitoring via Artificial Intelligence-Coupled Nanozymes

Abstract Safe water management requires rapid and highly sensitive analytical platforms capable of detecting contaminants in complex environmental matrices. Nanozymes are nanomaterials with enzyme-mimicking catalytic activity that offer remarkable advantages for field-deployable...

Informal care outside the household by older people and cardiovascular health of caregivers: A Cross-Sectional Analysis of the SHARE European study

Social isolation is an established cardiovascular risk factor, but the health implications of providing social support remain understudied. We examined whether informal care outside the household is associated with any self-reported cardiovascular disease. We conducted a cross-se...

Small Wonders: How Nanotechnology Is Redefining Shoulder and Elbow Surgery

Objective: Nanotechnology has been increasingly incorporated into shoulder and elbow surgery, from bioinductive collagen scaffolds for rotator cuff repair to nanostructured implant surfaces for arthroplasty and nanoparticle-functionalized sutures for elbow tendon repair. This rev...

Community Dwelling Cancer Survivors' Perception and Readiness for Advance Care Planning: An Interpretive Description Qualitative Study

ABSTRACT Aim This study aimed to explore perceptions and readiness to engage in advance care planning (ACP) among community‐dwelling cancer survivors. Design An interpretive description qualitative study with reflexive thematic analysis. Methods Cancer survivors who had completed...

Development and Validation of a Tool to Measure Documented Health Care Encounter Time

Importance Time toxicity, defined as the time patients spend receiving cancer treatment and interacting with health care systems, is an emerging treatment-related burden. Existing studies typically quantify time toxicity using health care contact days, which may inadequately capt...

Spectrally Tunable Zero-Dimensional Manganese–Antimony-Based Halide Solid-Solution Glasses for X-ray Imaging and Information Encryption

Abstract Despite significant advances in high-performance X-ray scintillators based on organic–inorganic hybrid metal halides (OIHMHs), realizing spectrally tunable luminescence within a single OIHMH system remains a formidable challenge for next-generation multifunctional photon...

Human-like content analysis for generative AI with language-grounded sparse encoders

The rapid development of generative AI has transformed content creation, communication, and human development. However, this technology raises profound concerns in high-stakes domains, demanding rigorous methods to analyze and evaluate AI-generated content. While existing analyti...

Associations between urban form and urban multifunctionality: a comparative study

Abstract Cities are complex and dynamic systems that integrate social, ecological, and infrastructure domains. This study investigates and quantifies how urban forms are associated with multiple urban functions across these domains, and how these associations combine into positiv...

Implementing reproductive carrier screening to include diverse Asian populations: insights from Singapore

Abstract Background As part of Singapore’s effort towards precision medicine tailored to Asian diversity, we describe the implementation of a nationwide reproductive carrier screening program. Using a customised 112-gene panel, targeting population-specific recessive genetic dise...

A framework for understanding automatic identification system (AIS) manipulation: purposes, goals, and strategies

Abstract There is increasing attention paid to the manipulation of ships’ Automatic Identification System (AIS) signals, with implications for maritime safety, law enforcement, and security. Based on the literature and narrative reports, this paper proposes a framework that answe...

Comparing language models and machine learning classifiers for detecting humorous vaccine misinformation on social media

Abstract Misinformation embedded in humor on social media can be difficult to detect and mitigate. This study investigates the effectiveness of traditional machine learning (ML) models, pre-trained neural language models, and large language models (LLMs) in identifying humor-lade...

Overcoming the mobility–reliability trade-off in BEOL-compatible In2O3-based FETs through synergistic doping and prolonged annealing

Oxide semiconductors field-effect transistors (OS FETs) capable of simultaneously delivering high mobility and excellent reliability are a key platform for high-performance circuits and memory modules in monolithic three-dimensional integrated circuits (M3D ICs). In this work, we...

Mask‐Free Electro‐Addressable Localization of GOx@ZIF‐8 on Prussian Blue Microelectrodes for Glucose Biosensing

Precisely integrating MOF powders into patterned electrochemical devices remains a processing challenge, as conventional methods often require masks, manual alignment, or poorly scalable steps and can lead to non-selective deposition and inefficient material use. While electropho...

Evaluation of Intervention Strategies to Improve Follow-Up Colonoscopy After Abnormal FIT/FOBT Result

Importance Colorectal cancer is the second leading cause of cancer mortality worldwide. Early detection through screenings has been shown to improve morbidity and mortality. While fecal immunochemical test (FIT) or fecal occult blood test (FOBT) are established cost-effective scr...

Dynamic and techno-economic assessment of solar-assisted biomass gasification for continuous hydrogen production

Solar-driven biomass gasification offers a promising route to produce green hydrogen while storing solar energy in chemical form. To mitigate solar intermittency, a solar/autothermal hybrid gasification strategy based on solar-input-dependent adjustment of gasifying-agent ratios...

Technical Note - A patient-specific implant for orbital wall reconstruction with infraorbital rim extension: Accuracy and proof-of-principle evaluation of an “one-fit-only” design

Accurate intraoperative positioning of patient-specific implants (PSI) in orbital wall reconstruction remains challenging due to residual translational and rotational freedom. The aim of this proof-of-principle study was to introduce an orbital PSI design refinement incorporating...

Enhancing combustion in an ethanol rotary engine via turbulent jet ignition: parametric study and mechanism analysis

Enhancing the combustion of ethanol rotary engine (ERE) is crucial for carbon neutrality. This study systematically compares the effects of conventional spark plug ignition mode (CSPIM) and turbulent jet ignition mode (TJIM) on the performance of an ERE. This investigation employ...

Integrated experimental-numerical characterization of thickness and loading condition effects on mechanical properties in copper thin films

Copper (Cu) thin films are critical interconnect materials in advanced semiconductor interconnect and packaging applications, where mechanical reliability under loading conditions relevant to semiconductor manufacturing and packaging becomes increasingly important with continued...

Bonding‐chemistry‐guided design of carbon frameworks for rechargeable‐ion batteries

Abstract Various carbon frameworks are central to rechargeable‐ion batteries, while continuous structural and compositional regulation provides broad opportunities to improve fast‐charging capability, storage capacity, and cycling stability. However, a unified chemistry‐based und...

Raman Self‐Tracking Copper Metal‐Organic Framework‐Based Nanoplatform for Cuproptosis Cancer Therapy

ABSTRACT Cuproptosis represents a promising strategy for cancer therapy, yet its clinical translation is hampered by unexpected deactivation and off‐target toxicity of copper ions during their delivery to tumors. We developed a copper metal‐organic framework‐based nanoplatform (C...