National University of Singapore

Mechanical Behavior of Layered Heterogeneous Hydrate-Bearing Sediments: Insights from Triaxial Experiments and Numerical Modeling

Abstract The mechanical behavior of natural gas hydrate-bearing sediments (HBS) is critical for safe and efficient gas production. However, marine HBS commonly exhibit layered heterogeneity caused by spatial variations in clay distribution and hydrate saturation (Sh), whose effec...

IgG4 ‐Related Disease Presenting as Inflammatory Midline Pseudotumor of the Face and Neck

A 78-year-old Chinese woman presented with a one-year history of a progressively enlarging purpuric rash over the central face and nasal dorsum, with subsequent development of a firm midline neck mass. Histopathology revealed dense lymphoplasmacytic infiltrate with fibrosis and o...

Magneto-mechano-electrochemical fiber for deformation-resilient and smart electronic textiles

Electronic textiles represent a transformative platform for integrating technology into daily wear, yet their development has been undermined by a fundamental challenge: the conflicting requirements between mechanical deformation for functionality and structural stability for per...

A Preconditioned Augmented Lagrangian Method for Solving Semidefinite Programming Problems

In this work, we propose a preconditioned augmented Lagrangian method (ALM) for solving semidefinite programming (SDP) problems. The preconditioner is implemented via a weighted penalty function in the ALM subproblem, with the weight matrix derived from the projection operator on...

Interaction between large-diameter offshore wind turbine monopiles and adjacent spudcan penetration and extraction in clay

Large-diameter monopiles are used for offshore wind turbines, while adjacent jack-up spudcan operations may induce soil deformation and compromise serviceability. Existing spudcan–pile interaction studies have focused on pile response during penetration, with limited attention to...

Recent Advances in Wearable Tactile Fiber Bragg Grating Sensors

With the advancement of wearable tactile technology, complex multi-site and multimodal sensing has become an inevitable trend [...]

Digitally Mediated Heritage Tourism for Sustainable Heritage Management: Evidence from the Liangzhu Heritage Site

How heritage tourism scenes evolve alongside digital mediation and how different forms of mediation are represented in visitor accounts remain insufficiently understood. This study examines the Liangzhu heritage site, centred on the Archaeological Ruins of Liangzhu City, using 71...

Improving allergic rhinitis symptoms through nutrition as an adjunct: a systematic review and meta-analysis on the efficacy of dietary supplements

Dietary supplements are increasingly explored as adjunctive strategies for allergic rhinitis (AR). This systematic review and meta-analysis evaluated the efficacy of dietary supplementation in improving AR symptoms and explored potential underlying mechanisms. A systematic PubMed...

Patient perceptions of emergency department versus GP visits and of GPFirst: a qualitative study

Abstract Introduction: Overcrowding in emergency departments (EDs) has long been a concern, contributing to adverse outcomes. To address inappropriate attendances, Changi General Hospital (CGH) introduced GPFirst, a programme that encourages patients with mild conditions to visit...

Hardness-based resistance model for predicting penetration depths by rigid projectiles on various cement-based materials

With the development of advanced cement-based composites, conventional penetration models based primarily on uniaxial compressive strength have become increasingly inadequate. Although many empirical or semi-empirical models have been refined for specific concrete types, their ac...

Finite-Size Accuracy and Engineering Applicability of Equivalent Continuum Models for BCC Lattice Structures

Equivalent continuum models provide an efficient alternative to explicitly resolving the internal architecture of lattice structures, but their accuracy in finite components depends strongly on structural scale, boundary effects, constitutive behavior, and numerical discretizatio...

Control of axial dispersion in polymeric flows: Magnetic effect versus electro-osmotic effect

Since Taylor’s seminal work on the dispersion of soluble matter, the modelling and control of solute dispersion have received considerable attention. This study investigates the solute dispersion in polymer solutions driven by unsteady magnetohydrodynamic (MHD)-oscillatory electr...

Coffee-ring effect enables correlative super-resolution imaging of label-free chromosomes

High-resolution chromosome imaging plays a key role in understanding chromosome structure. However, traditional methods for super-resolution (<200 nm) chromosome imaging are often complex and time-consuming, requiring purification, staining or sectioning of chromosomes. Here, we...

Convergent genome streamlining accompanies independent miniaturization in the world’s smallest fishes

Miniaturization, the reduction of adult body size to an extreme degree, has evolved repeatedly across vertebrates. Yet its genomic underpinnings remain poorly understood. Cypriniformes, the most species-rich order of freshwater fishes, contains multiple miniaturized lineages that...

3D Microfluidic Networks Formed by Mechanically Guided Compressive Buckling for Large‐Scale Perfused Tissue Culture

ABSTRACT Engineered tissues and organoids offer transformative potential for drug screening and regenerative medicine, yet their application is constrained by limited size and slow maturation. Despite the development of various channel networks for large‐scale engineered tissue p...

Computationally Guided Design of Facet-Defined Multielement Active Sites on Hexagonal Close-Packed High-Entropy-Alloy Nanosheets for Alkaline Hydrogen Evolution

Abstract Nonconventional hexagonal close-packed (HCP) high-entropy alloys (HEAs) provide distinct catalytic surfaces, but their synthesis with well-defined facets remains challenging, leaving facet-dependent multielement ensemble effects largely unexplored. Here, we report the co...

Digital service providers, emerging e-retailers, and rent creation and capture in cross-border e-commerce ecosystem

The rise of emerging e-retailers in cross-border e-commerce reflects shifting competitive dynamics in digital ecosystems long dominated by global platform giants. To recalibrate attention from incumbent platform giants to digital service providers (DSPs) and emerging e-retailers,...

Higher-Order Boundary Conditions for Atomistic Dislocation Simulations

Abstract. We present a higher-order boundary condition for atomistic simulations of dislocations that address the slow convergence of standard supercell methods. The method is based on a multipole expansion of the equilibrium displacement, combining continuum predictor solutions...

Deciphering Cellular and Spatial Regulatory Identities from Sparse Chromatin Accessibility Landscapes

Abstract Chromatin accessibility profiling provides a powerful view of regulatory landscapes across heterogeneous biological systems, enabling the investigation of cell-state diversity and spatially organized regulatory programs. However, deciphering meaningful regulatory identit...

Targeting MDA5 induces immunogenic cell death and promotes anti-tumor immunity

Identifying targets to enhance tumor immunity is an urgent need. Although nucleic acid sensors play critical roles in promoting tumor immune clearance, their exceptionally low mutation rate in cancers suggests potential unexplored roles in tumor progression. Here, we demonstrate...