National University of Singapore

Selective transport of plasma-derived reactive species through the plant aquaporin channels: a molecular dynamics study

Abstract The selective permeability of reactive oxygen and nitrogen species (RONS), generated by cold atmospheric plasma (CAP), through plant aquaporins was investigated to identify plasma-derived species capable of intracellular delivery. Using atomistic molecular dynamics and e...

Classical Theories in the Hands of the Everyday: Lay Perceptions of Aging Well and Retirement in Singapore

Abstract For decades, gerontologists have competed to objectively define the ideal later life, often eliding the subjective perspectives of older adults. Yet, definitions of successful aging are only meaningful intersubjectively, making lay evaluations crucial to ground theoretic...

Scratching Lithography: In Situ Mechanical Exfoliation of van der Waals Materials for Direct‐Write Circuits

ABSTRACT Ever since the discovery of graphene via mechanical exfoliation of graphite, 2D nanomaterials have garnered wide interest for high‐performance electronics. Mechanical exfoliation of van der Waals (vdW) layered materials produces nearly perfect 2D nanomaterials, yet their...

“Swab-and-Stain” Nanoparticle Assay for Detection of PBP2a-Expressing Methicillin-Resistant Staphylococcus aureus Toward Point-of-Need Environmental Surveillance

Surveillance of methicillin-resistant Staphylococcus aureus (MRSA) in the environment is crucial for reducing its transmission, particularly in hospitals, nursing homes, and high-contact public areas. Rapid Point-of-Need (PON) tools at healthcare facilities, without involving pro...

Early adolescent self-harm: examining prevalence and risk factors in a multi-ethnic Asian birth cohort

Abstract Background Early adolescence marks a vulnerable developmental phase for the emergence of self-harm behaviours, which can potentially be life-threatening. However, the prevalence and risk factors of early adolescent self-harm, particularly in non-Western community-based p...

Understanding Barriers and Motivators of Familial Hypercholesterolemia Genetic Testing: Insights From the Singapore Public

Familial hypercholesterolemia (FH) is a common monogenic disorder associated with elevated low-density lipoprotein cholesterol and premature cardiovascular disease. Despite Singapore's high FH prevalence and the launch of the National FH Genetic Testing Programme in 2025, uptake...

Optimal Strain Combinations for Prognostic Prediction in Pulmonary Arterial Hypertension

BACKGROUND: Strain parameters are sensitive indicators of myocardial performance, but the optimal combination for prognostic prediction in pulmonary arterial hypertension remains unclear. METHODS: Patients diagnosed with pulmonary arterial hypertension between June 2013 and June...

Reducing Spatial and Temporal Dimensionality in the Multidimensional Caldeira-Leggett Model

Focusing on the real-time dynamics of the reduced density matrix of the multidimensional Caldeira-Leggett model, several techniques are adopted in this paper to reduce the spatial and temporal dimensionality, combined into an efficient algorithm. From a spatial perspective, an eq...

Intermediate habitat fragmentation reduces gastropod movement in experimental intertidal landscapes: implications for fragmentation–diversity relationships

Abstract Context Understanding how habitat configuration influences biodiversity is central to landscape and seascape ecology, yet experimental tests that isolate fragmentation per se from habitat area remain rare. In an earlier experiment that disentangled the effects of habitat...

AI4AI Survey: From Long-Horizon Agents to Recursive Self-Improvement — Definitions, Reliable Horizons, and Open Problems

Can AI improve AI? AI agents can now run experiments, modify code and training pipelines, and iteratively improve AI artifacts. Yet the literature remains fragmented across long-horizon agents, AI for AI (AI4AI), self-improvement, and recursive self-improvement, making it difficu...

The Molecular Footprint of Thrombosis: What Does Myocardial Platelet Imaging After STEMI Tell Us?

Heerajnarain Bulluck, MBBS PhD, Derek J Hausenloy, MBChB PhD; The Molecular Footprint of Thrombosis: What Does Myocardial Platelet Imaging After STEMI Tell

A Machine Learning Framework for Retrieving Atmospheric Composition and the Associated Averaging Kernels From a Geostationary Hyperspectral Infrared Sounder

Abstract Geostationary hyperspectral infrared sounders provide hourly observations of the atmospheric composition. However, the conventional optimal estimation method (OEM)‐based retrieval algorithm requires computationally expensive radiative transfer calculations and inverse mo...

Reframing HRM for a multipolar world: insights from the Asia-Pacific region

Purpose The purpose of this anthology is to critically evaluate the role of human resource management in International Business within an increasingly multipolar, digitally disrupted and institutionally diverse global environment. By bringing together leading scholars, the collec...

Lack of Efficacy of Low‐Dose Cyclobenzaprine on Electromyographic Activity Related to Sleep Bruxism: A Randomized Crossover Double‐Blind Placebo‐Controlled Clinical Trial

Sleep bruxism (SB) is a motor activity characterized by repetitive masticatory muscle contractions during sleep, commonly associated with tooth damage and jaw pain or headache. Pharmacological management strategies targeting its central nervous system-related mechanisms remain li...

Milvexian with Antiplatelet Therapy after Acute Coronary Syndrome Event

BackgroundPatients are at increased risk for recurrent ischemic events after an acute coronary syndrome event. Milvexian, an oral factor XIa inhibitor, may reduce the risk of major adverse clinical events with minimal bleeding risk. MethodsIn this phase 3, randomized, placebo-con...

Plasmonic-enhanced lanthanide nanotransducers for mid-infrared detection

Advanced mid-infrared (MIR) detection underpins a wide range of applications from chemical sensing to thermal imaging. Conventional MIR photodetectors rely on narrow-bandgap semiconductors that typically require cryogenic cooling, whereas uncooled alternatives suffer from inheren...

Asian Neurogastroenterology and Motility Association and Asia-Pacific Association of Gastroenterology Chronic Constipation Consensus 2026.

Background/Aims: : Chronic constipation is a common gastrointestinal (GI) disorder in Asia, characterized by heterogeneous symptom presentation, frequent overlap with other GI symptoms, and limited access to specialized diagnostic tests in many settings. These factors contribute...

Geographic and perceptual bias in multimodal LLMs: evidence from a global dataset spanning more than 200 cities

Multimodal large language models (MLLMs) are increasingly deployed for urban informatics applications, from objective built environment attribute extraction to subjective assessments. However, do MLLMs apply the same standards across regions while executing these urban-related ta...

High‐Temperature Alloys in Aeroengines: Damage and Fracture Insights From Micromechanical Modeling

ABSTRACT High‐temperature alloys are the cornerstone of aeroengine hot‐section components, where extreme thermomechanical conditions give rise to intricate damage and fracture behaviors that critically limit the structural integrity of whole aeroengines. Generally, Ni‐based super...

Tunnel field-effect transistors exhibiting performance beyond the Boltzmann thermionic limit

The International Roadmap for Devices and Systems (IRDS) has identified the tunnel field-effect transistor (TFET) as the most promising next-generation logic device that enables sustainable downscaling in driving voltage and power consumption. Demonstrating an acceptable sub–Bolt...