Monash University

Latent profile analysis of postpartum depression symptoms and its associations with weight stigma and eating behaviors among postpartum women in China

Abstract Background Postpartum depression (PPD) represents a significant maternal health challenge with diverse symptom manifestations. Traditional analytical approaches that treat postpartum women as a homogeneous group may obscure distinct symptom patterns, limiting the develop...

Bedside assistant models in robotic abdominal and pelvic surgery: a systematic review of operative efficiency, training exposure, and perioperative safety

Robotic surgery depends on effective bedside assistance, yet staffing models vary between physician and non-physician assistants. We systematically reviewed comparative evidence evaluating these models in robotic abdominal and pelvic surgery. A PRISMA compliant systematic review...

Protective role of dietary antioxidant intake on long-term effects of extreme PM2.5 exposure on respiratory health

Objective: To test whether dietary antioxidants moderated effects of PM 2.5 from coal mine fire smoke on respiratory symptoms. Methods: We conducted cross-sectional analyses of diet and respiratory symptom data from 448 members of the Hazelwood Health Study Adult cohort. Individu...

Ag-iPyramidSERS Enables Single-Particle Detectionof Sub-200 nm Nanoplastics in Real Samples

Abstract The detection of nanoplastics smaller than 200 nm is critical because of their potential to cross biological barriers, yet it remains a significant analytical challenge in complex environmental matrices due to weak signals and matrix interference. Here, we developed an o...

Inaccuracy of self-reported migraine: insights from 601 paired assessments from a single-centre study in Australia

Both clinical and research settings may rely on accurate self-diagnosis of migraine for medical triage, population-based surveys or epidemiological studies. Unfortunately, accessing neurologists for diagnosis may be cost-prohibitive, delayed due to workforce shortages or impracti...

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

ABSTRACT CEP55, a centrosomal protein frequently overexpressed in multiple cancers, is implicated in regulation of genomic instability and PI3K/AKT pathway activation, yet its role in tumor progression and the tumor microenvironment remains incompletely defined. Here, we develope...

The Effect of Antenatal Paracetamol on Breathing Effort of Premature Infants at Birth: A Feasibility Trial

Background: Prostaglandin E2 (PGE2) suppresses perinatal breathing. Reducing antenatal PGE2 concentrations with paracetamol could stimulate spontaneous breathing in premature infants at birth. We aimed to assess feasibility and potential effects of antenatal paracetamol. Methods:...

Relationship between neck weakness in motor neurone disease and respiratory function: a retrospective study

AIMS: The primary aim was to explore the relationship between neck weakness in people with motor neurone disease (MND) and their respiratory function. The secondary aim was to identify whether neck weakness can be a prognostic factor. METHODS: This was a retrospective observation...

‘So many relationships in the room’: Participant perspectives on the affordances and challenges of co‐therapy in psychedelic assisted therapy

OBJECTIVES: Psychedelic-assisted therapy (PAT) frequently utilises a "cotherapy" model, in which two therapists jointly support participants throughout dosing and psychotherapy sessions. While common in clinical trials, participant experiences of cotherapy remain underexplored. T...

Characterising the Beyond 50 Cohort: Preliminary Exploration of Physical and Psychosocial Health Factors and Substance Use Among a Cohort of Community Dwelling Adults Aged 50–70 Years

ABSTRACT Introduction Older adults exhibit unique risks associated with poor mental health and substance use. The Beyond 50 study is a longitudinal cohort investigating the determinants of healthy ageing, including relationships between physical and psychosocial health and substa...

User perspectives and scales for collaborative classification tasks in immersive environments

Immersive technologies offer the possibility of facilitating collaboration through new capabilities, like shifting between different scales or perspectives while keeping a first-person view of the workspace. All these features affect collaboration by influencing user behaviour, s...

Associations between metabolic dysfunction–associated steatotic liver disease and physical and mental health–related quality of life in older adults

Metabolic dysfunction–associated steatotic liver disease (MASLD) is a common, often overlooked liver condition. Its impact on quality-of-life in older adults is not well understood. We examined the association between MASLD and physical and mental quality of life in a well-charac...

Defining and Measuring Developmental Regression During Childhood: A Scoping Review

ABSTRACT Developmental regression during childhood is inconsistently defined and measured, resulting in delayed diagnostic discovery and intervention. This study aimed to examine published definitions and measures for developmental regression. A comprehensive search strategy was...

Accountability without an Oracle: ScholarHound for LLM-Produced Scientific Commitments, and Why Claim-Level Gold Is the Binding Constraint

Scientific language-model systems increasingly retrieve papers and write evidence-backed syntheses, yet their judgments are checked by the same class of models that produced them. We present ScholarHound, an accountability layer separating model-mediated interpretation from autho...

Efficacy of Vitamin C Treatment to Aid the Healing of Foot Ulcers in People With Diabetes: A Randomised, Placebo‐Controlled Double‐Blind Trial: The FOOT‐C Study Protocol

ABSTRACT Introduction Diabetes‐related foot ulceration (DFU) is a serious complication, serving as a leading cause of amputation, disability, hospitalisation and a significant contributor to healthcare costs. Deficiencies in vitamin C and other micronutrients are common in DFU. E...

Metabolic reprogramming enables transient survival and envelope remodelling in Staphylococcus aureus under dalbavancin treatment

Clinical failure of antibiotic therapy can occur in the absence of measurable resistance, yet the biological basis of this discordance remains poorly understood. Here, we identify a transient survival phenotype that limits dalbavancin efficacy and may contribute to treatment fail...

Machine Learning for Residential Energy Data Analytics Enhancing Energy Efficiency and Management: Datasets, Methods, and Applications

Abstract Purpose of Review Residential energy analytics has advanced with increasing availability of energy data, e.g., from smart meters, to provide new insights into consumption behaviors and enhance energy efficiency and management. This review synthesizes public datasets, mac...

An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation

Heterozygous carboxyl-terminal variants in the RHO guanosine triphosphatase (GTPase) CDC42 are known to cause severe autoinflammatory syndromes. Here, we identified a heterozygous amino-terminal p.T43I (Thr 43 →Ile) CDC42 variant in patients with autoinflammation and uncovered a...

Strain Effectson the Mechanical Properties and GasAdsorption and Diffusion Characteristics of Anthracite

Abstract The coal matrix is subjected to complex strain conditions during exploration. Pore structural evolution, gas adsorption, and diffusion characteristics of high-rank coal matrix under uniaxial compressive and tensile strain conditions are investigated through molecular sim...

Issues in the clinical assessment and management of people living with motor neurone disease (MND): a survey of Australian healthcare professionals

Objective: To inform the development of the Australian MND Guideline, this study aimed to identify challenges Australian healthcare professionals (HCPs) face in the clinical assessment and management of people living with MND (plwMND) including where practice varies from evidence...