Institution
Monash University
Recent research
- Health & MedicineOpen access
Both clinical and research settings may rely on accurate self-diagnosis of migraine for medical triage, population-based surveys or epidemiological studies. Unfortunately, accessing neurologists for diagnosis may be cost-prohibitive, delayed due to workforce shortages or impracti...
- Society & EconomicsOpen access
OBJECTIVES: Psychedelic-assisted therapy (PAT) frequently utilises a "cotherapy" model, in which two therapists jointly support participants throughout dosing and psychotherapy sessions. While common in clinical trials, participant experiences of cotherapy remain underexplored. T...
- Society & EconomicsOpen access
ABSTRACT Introduction Older adults exhibit unique risks associated with poor mental health and substance use. The Beyond 50 study is a longitudinal cohort investigating the determinants of healthy ageing, including relationships between physical and psychosocial health and substa...
- AI & ComputingOpen access
User perspectives and scales for collaborative classification tasks in immersive environments
Immersive technologies offer the possibility of facilitating collaboration through new capabilities, like shifting between different scales or perspectives while keeping a first-person view of the workspace. All these features affect collaboration by influencing user behaviour, s...
- Health & MedicineOpen access
Metabolic dysfunction–associated steatotic liver disease (MASLD) is a common, often overlooked liver condition. Its impact on quality-of-life in older adults is not well understood. We examined the association between MASLD and physical and mental quality of life in a well-charac...
- AI & ComputingOpen access
Scientific language-model systems increasingly retrieve papers and write evidence-backed syntheses, yet their judgments are checked by the same class of models that produced them. We present ScholarHound, an accountability layer separating model-mediated interpretation from autho...
- Health & MedicineOpen access
Defining and Measuring Developmental Regression During Childhood: A Scoping Review
ABSTRACT Developmental regression during childhood is inconsistently defined and measured, resulting in delayed diagnostic discovery and intervention. This study aimed to examine published definitions and measures for developmental regression. A comprehensive search strategy was...
- Health & MedicineOpen access
ABSTRACT Introduction Diabetes‐related foot ulceration (DFU) is a serious complication, serving as a leading cause of amputation, disability, hospitalisation and a significant contributor to healthcare costs. Deficiencies in vitamin C and other micronutrients are common in DFU. E...
- Biology
An autoinflammatory CDC42 variant M45L demonstrates the mechanism of pyrin inflammasome activation
CDC42 is an evolutionarily conserved guanosine triphosphatase (GTPase) regulating critical cellular and immune processes. Variants in CDC42 therefore cause a spectrum of developmental phenotypes, including hematological and immunological symptoms. Here, we identify a previously u...
- Biology
An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation
Heterozygous carboxyl-terminal variants in the RHO guanosine triphosphatase (GTPase) CDC42 are known to cause severe autoinflammatory syndromes. Here, we identified a heterozygous amino-terminal p.T43I (Thr 43 →Ile) CDC42 variant in patients with autoinflammation and uncovered a...
- Society & EconomicsOpen access
Historical Anti-Fascism and Right-Wing Voting in Italy
We study how anti-fascist opposition during Mussolini’s dictatorship affects post-war support for right-wing parties in Italy. We construct a measure of anti-fascism from the universe of recorded opponents, and use newly digitized historical data to resolve simultaneity between t...
- Health & MedicineOpen access
Clinical failure of antibiotic therapy can occur in the absence of measurable resistance, yet the biological basis of this discordance remains poorly understood. Here, we identify a transient survival phenotype that limits dalbavancin efficacy and may contribute to treatment fail...
- Health & MedicineOpen access
Objective: To inform the development of the Australian MND Guideline, this study aimed to identify challenges Australian healthcare professionals (HCPs) face in the clinical assessment and management of people living with MND (plwMND) including where practice varies from evidence...
- Engineering & TechnologyOpen access
Abstract Purpose of Review Residential energy analytics has advanced with increasing availability of energy data, e.g., from smart meters, to provide new insights into consumption behaviors and enhance energy efficiency and management. This review synthesizes public datasets, mac...
- Engineering & Technology
Abstract The coal matrix is subjected to complex strain conditions during exploration. Pore structural evolution, gas adsorption, and diffusion characteristics of high-rank coal matrix under uniaxial compressive and tensile strain conditions are investigated through molecular sim...
- Health & Medicine
The Effect of Using Write‐Zoom for Volume Flow Measurements in Haemodialysis Fistulas
ABSTRACT Introduction Arteriovenous fistulas (AVFs) are crucial for patients undergoing haemodialysis, yet about 25% fail to mature or experience early failure. Ultrasound is key in managing AVFs, with volume flow (Qa) serving as a predictor of maturation. Accurate Qa measurement...
- Physics & SpaceOpen access
Precise initiation and synchronization of chemical reactions in free space remain major challenges for time-resolved studies in structural biology, chemistry, and materials science. Although modern probes provide femtosecond resolution, experimental access to early reaction dynam...
- Health & MedicineOpen access
Staphylococcus aureus strains have emerged with resistance mechanisms that reduce the efficacy of last resort antibiotics and evade the immune system. One strategy to combat antimicrobial resistance is to modulate host immunity to eliminate infections more effectively. This has l...
- Health & Medicine
Background Knowledge brokers act as intermediaries to bridge evidence-to-practice gaps. Limited evidence describes how the knowledge broker role in health settings evolves over time. This study aimed to (a) examine the evolution of knowledge broker activities over a 12-month impl...
- Physics & Space
The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,200 new measurements from 903 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and b...