Instituto de Salud Carlos III

Barriers and facilitators to advance care planning implementation: a qualitative interprofessional study in the Spanish public health and social care system

Advance Care Planning (ACP) is essential for improving the quality of end-of-life care. Despite having a well-established legal framework, the implementation of ACP in Spain is limited and largely bureaucratic. The existing literature has primarily focused on knowledge deficits a...

Smoking cessation experiences during alcohol and cannabis treatment in substance use programmes in Catalonia: A qualitative study

Tobacco use remains disproportionately high among people receiving treatment for alcohol or cannabis use, yet it is rarely addressed in substance use services. This study explored the lived experiences of people who smoke while undergoing treatment for alcohol and/or cannabis use...

Mitochondrial aggregates as a novel quality control mechanism and potential relationship to lipofuscinogenesis

Mitochondria employ quality control mechanisms to maintain homeostasis. Under chronic stress, these systems become overwhelmed, causing intramitochondrial aggregates formation. As a potential quality control process when canonical pathways are compromised, we propose a model of m...