Humboldt-Universität zu Berlin

Mode variation in clausal complexity in German and Persian

Abstract This paper revisits the question of mode as an influencing factor for variation in clausal complexity. In a comparative corpus study using the Lang*Reg corpus, clausal embedding is compared between the phonic and graphic mode produced by the same language users with the...

Mechanisms and therapeutic strategies of asthma: from bench to bedside

Asthma is a heterogeneous chronic airway disease arising from a complex interplay of genetic susceptibility and environmental exposures. Key pathobiological features include dysregulated immune responses (particularly type 2 inflammation), structural airway remodeling, and mucus...

Cell SurfaceDeazaflavin-Diazirine Energy-Transfer(DarT) Photoproximity Labeling Using Antibody Conjugates

Abstract Elucidating protein–protein interactions plays a crucial part in understanding disease mechanisms and advancing pharmacological research. Photocatalytic proximity labeling using antibody–catalyst conjugates enables the highly target-specific analysis of protein–protein i...

Caregiver-reported experience of integrated care for children with special health care needs and its sociodemographic, health- and network-related correlates in Germany: Cross-sectional results from the PART-CHILD cohort

Abstract Background Children with special health care needs (CSHCN) often rely on cross-sectoral care networks involving medical, therapeutic, educational, and social services. However, key dimensions of integrated care, including cross-sectoral communication and attention to fam...

Evaluating clinical and neuroimaging predictors for cognitive-behavioral therapy outcome in obsessive-compulsive disorder

Abstract Cognitive-behavioral therapy (CBT) is the first-line treatment for obsessive-compulsive disorder (OCD), yet a significant number of patients do not achieve remission or substantial symptom relief. This study aims to enhance the prediction of CBT outcomes in OCD by integr...

Narrating mellowness? Political soundness of “Chinese schools” of international relations

Abstract The rise of China has sparked growing scholarly interest in its political and philosophical thought, including the “Chinese schools” of international relations (IR). With this article, we add to the scholarship by asking two questions: which of these schools are mobilise...

Developmentof a FRET-Based Assay for Human NeutralSphingomyelinase 2

Abstract Neutral sphingomyelinase 2 (nSMase2) is a membrane-bound enzyme that hydrolyzes sphingomyelin (SM) into ceramide and phosphocholine. By generating the bioactive lipid ceramide, nSMase2 plays a critical role in cell stress responses and in regulating exosomes that package...

Maternal sensitivity supports infant sleep: evidence from two longitudinal prospective cohorts on maternal childhood maltreatment, maternal sensitivity, and infant sleep

Maternal childhood maltreatment (CM) has been linked to adverse outcomes in the next generation, including infant sleep, which is crucial for healthy development. This study examined whether maternal sensitivity buffered these effects in 101 German and 117 U.S. mother-infant dyad...

The impact of an intensive care telemedicine program on weaning from invasive ventilation: a secondary analysis of the ERIC trial

Abstract Background ICU patients commonly require invasive mechanical ventilation. Although weaning from ventilation is crucial for patient outcomes, it is commonly not performed according to guideline recommendations. We investigated if a complex telemedicine intervention improv...

Is self-reported daylight exposure reliable? A validation study with actigraphy in urban environments

Daylight exposure is an environmental determinant of human health, yet measuring real-world exposure at scale remains a major challenge. Large population studies frequently rely on self-reported time spent outdoors as a proxy for daylight exposure, although the validity of this m...

Review of Particle Physics *

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,200 new measurements from 903 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and b...

Outside Back Cover: Cycloazulenylene

Cycloazulenylene exhibits a remarkably narrow HOMO–LUMO gap, intense absorption in the visible range, and a unique tubular packing in the solid state. In Research Article e2204400, Tomáš Slanina, Oliver Dumele, and co-workers strained the nonalternant azulene, known for its anti-...

EFECT enables reliable and reproducible stochastic simulations across disciplines

Stochastic simulations underpin computational research in fields from systems biology and epidemiology to finance and physics-informed machine learning, yet their reproducibility is hard to quantify because each run yields different outcomes. Existing practices to improve computa...

Thyroid disorders, thyroid autoimmunity, and anxiety—a systematic review and meta-analysis of population-based studies

Objectives Previous studies, largely based on case–control samples, have suggested that hypothyroidism, hyperthyroidism, and thyroid autoimmunity may be associated with an increased risk of anxiety. However, whether a true association exists remains unclear, as population-based s...

Testing the reliability of a camera‐trap based abundance proxy for assessing mountain ungulate populations

Abstract Monitoring wildlife abundance is important for understanding species population status and trends and, thus, for informing conservation planning and wildlife management. Yet, abundance monitoring can be challenging and costly to implement, particularly for wildlife of co...

A perioperative management elective as a transition-to-practice intervention: effects on preparedness, professional identity, and career decision-making

Abstract Background Perioperative management requires a broad range of knowledge and practical skills essential for early clinical practice, yet perioperative care is often taught in fragmented rather than integrated fashion across undergraduate medical curricula. Beyond technica...

Visible injury patterns in relation to reported sexual acts after sexual assault: a retrospective cohort study

Sexual assault may result in visible anogenital and extragenital injuries, but the absence of such findings remains a major challenge in forensic interpretation. This retrospective forensic outpatient study analyzed 306 adults examined after reported sexual assault at the Violenc...

Chiroptera Personality—A Guide for Assessing Personality Variation in Bats: Ecological, Methodological and Statistical Considerations

ABSTRACT Consistent between‐individual differences, that is, animal personality (AP) is among the fastest‐growing topics in behavioural biology, with theoretical and empirical work showing important consequences for ecology, evolution and conservation. Yet bats—the second‐largest...