Humboldt-Universität zu Berlin

Diagnosing autoimmune encephalitis in psychiatry: clinical recommendations and unresolved challenges from the GENERATE network

Psychiatric syndromes can be caused by underlying autoimmune encephalitis (AE). This represents a diagnostic challenge at the interface of psychiatry and neurology. While AE mostly manifests with a combined, complex neuropsychiatric syndrome, some patients with AE may (initially)...

Time- and Frequency-Domain Study for Electron Beams Penetrating Dielectric Nanospheres: Fingerprints of Cherenkov and Transition Radiation

Abstract We present a theoretical study of Cherenkov and transition radiation for swift electron beams penetrating dielectric nanospheres using material models of different sophistication. Specifically, we perform a combined time-domain (numerically, via the discontinuous Galerki...

From Diagnosis to Long-Term Survivorship: A Scoping Review of Specialist or Advanced Nursing Roles in Gynecologic Oncology

OBJECTIVES: Due to rising survival rates in gynecologic cancers, the need for holistic, patient-centered, and multidisciplinary survivorship care is increasing. Evolving specialist or advanced nursing roles can help to improve quality of life within the interprofessional care tea...

Ferulic acid – A promising candidate molecule for the treatment of colitis

Ulcerative colitis is an inflammatory bowel disease of multi-factorial etiology and responsible for considerable health and socioeconomic burdens given high global prevalence rates. Since current therapy options are associated with various side effects, alternative or adjunct the...

Which aspects of continuity of care in primary care are associated with better self-rated health? A cross-sectional study among older adults in Berlin

Abstract Background Global population ageing and rapid urbanization are increasing the prevalence of multimorbidity and complex health needs among older adults, emphasizing the importance of accessible and high-quality primary care. Continuity of care (CoC) is a core feature of p...

Pontryagin Maximum Principle for Rough Stochastic Systems and Pathwise Stochastic Control

Abstract. We analyze a novel class of rough stochastic control problems that allows for a convenient approach to solving pathwise stochastic control problems with both nonanticipative and anticipative controls. We first establish the well-posedness of a class of controlled rough...

Parental needs and experiences with e-Health applications in chronic pediatric care – a scoping review

Abstract Background The number of children and adolescents living with a chronic condition is steadily increasing. These conditions often place a considerable burden on affected individuals and their families. E-Health applications have the potential to support families by provid...

Disentangling Electronic and Lattice Contributions to Transient Absorption in Metal Halide Perovskites: A First-Principles Study of CH3NH3PbBr3

Abstract Soft lattices combined with strong electron–phonon coupling in metal halide perovskites result in a complex interplay between electronic and lattice degrees of freedom. This interplay complicates the interpretation of time-resolved spectroscopic signals, such as transien...

Synchronization of topological signals in higher-order adaptive multilayer network

The study of synchronization in complex systems has recently been revolutionized by incorporating higher-order interactions through simplicial complexes. Building in particular upon the higher-order Kuramoto model, which considers oscillators on nodes, links, and higher-dimension...

Personality traits of entrepreneurs and the size of their firms

Abstract Personality research in entrepreneurship often focuses on venture entry and survival, leaving personality traits associated with firm size underexamined. Using novel data from the German Socio-Economic Panel that include a sample of owner-managers running larger firms, w...

Psychotherapy remission prediction models show limited cross-clinic generalizability in routine outpatient care

Abstract Clinical prediction models for psychotherapy outcomes have the potential to assist therapists in planning a patient’s individual treatment, but their clinical utility depends on maintaining predictive performance across settings. We assessed prediction of post-treatment...

Real-world use of bempedoic acid for hypercholesterolaemia: a German multicentre, retrospective, cohort study

Abstract Background Dyslipidaemia remains a leading cause of death in Germany despite an improving therapeutic landscape, with many patients not achieving guideline-recommended low-density lipoprotein cholesterol (LDL-C) goals. Bempedoic acid, an adenosine triphosphate citrate ly...

Clinical outcomes of a two-piece zirconia dental implant system

Abstract Background Data on market-available two-piece zirconia (ZrO₂) dental implants are limited. Therefore, the aim of this retrospective study was to evaluate the clinical performance of a commercially available ZrO₂ implant system over a 24-month period. Materials and method...

SARS-CoV-2 and RSV external quality assessment on molecular detection and variant typing in European expert laboratories in 2025

ABSTRACT We herein report on the fourth SARS-CoV-2 wet-lab external quality assessment (EQA) and the second organized by the AURORAE consortium to assess the diagnostic capabilities of European expert public health laboratories. Diagnostic capabilities were investigated regarding...

Increased firing rates monotonically expand neuronal coding bandwidth

Sensory information is often processed by populations of neurons that vary with respect to their levels of spiking activity. It appears plausible that neurons that fire more often are capable of following faster changes in the input signal than those with lower firing rates. In t...

Presenting Jesus through Direct Speech: Vergegenwärtigung in the Gospel according to Mark

Scholars of the New Testament are, first and foremost, textual and literary scholars – philologists of religious texts charged with the hermeneutical task of interpreting documents from a distant ancient world. 2 At its core, our task is to engage these texts in full length, in t...

Impact of the Confinement Strength on the Energy Spectra of Two Atoms Interacting via Zero-Range or Realistic Potentials

Abstract This work analyzes the influence of an external confinement on the energy spectrum of two interacting ultracold atoms, considering either a regularized contact or a more realistic Born-Oppenheimer potential. For two harmonically confined particles with contact interactio...

Site-specific controls predominate over erosion effects on nitrogen turnover: Evidence from 15N tracing in the field

Understanding how nitrogen (N) cycling is affected by soil erosion is essential to optimize N supply for crops and reduce losses in hilly fields. While topography-related impacts on N availability and losses have been studied, the mechanisms linking erosion to N transformation dy...

An easy-to-use laryngostroboscopy index for unilateral vocal fold paralysis reflects voice quality

BACKGROUND: To date, laryngostroboscopic parameters have been rarely used as outcome measures in clinical interventional studies, due tomethodological difficulties. METHODS: We applied a greatly reduced laryngostroboscopy evaluation protocol to an intervention study for unilatera...

Regular Linear Time Varying DAEs are Equivalent to DAEs in Strong Standard Canonical Form

The relationship between solvability of linear diffential-algebraic equations (DAEs) and their transformability into canonical forms has been investigated for more than forty years. After a comparative analysis of numerous DAE frameworks the notions regularity and almost regulari...