Huazhong University of Science and Technology

High-field magnetotropic signatures of spin and orbital-current magnetism

Abstract Magnetic anisotropy encodes key information about the angular dependence of the magnetic free energy, but its quantitative characterization often requires probes beyond conventional magnetometry. Magnetotropic susceptibility offers a thermodynamic route to this problem....

Bladder Sensory Neurons as Regulators of Neuro-Immune-Urothelial Interactions: From Molecular Mechanisms to Targeted Therapy for Neurogenic Bladder and Interstitial Cystitis/Bladder Pain Syndrome

Bladder sensory neurons are essential components of lower urinary tract sensory encoding and micturition reflex control. They detect bladder filling, stretch, inflammatory mediators, and pathogen-associated stimuli, and they communicate with urothelial cells, immune cells, and st...

Parenting styles and fertility intention: Mediating effects of childbearing beliefs and psychological resilience

China's declining fertility rate is partly due to low fertility intention among childbearing population. To understand family influence on young people's fertility intention and its underlying mechanisms, this study examines how parenting styles (authoritarian vs. permissive) aff...

A prognostic model for pyrrolizidine alkaloids-induced hepatic sinusoidal obstruction syndrome based on sarcopenia

Sarcopenia has been shown to be associated with the prognosis of patients with liver cirrhosis, hepatocellular carcinoma, liver failure. However, the impact of sarcopenia on survival has not been investigated in patients with pyrrolizidine alkaloids (PAs)-induced hepatic sinusoid...

Nonlocal dielectric response and screening in ionic liquids

The dielectric response of room-temperature ionic liquids (RTILs) plays a central role in charge screening within these strongly correlated ionic fluids and thereby governs ion transport, electrochemical kinetics, solubility, and related electrochemical phenomena. Here, we presen...

Multimodal Exploratory Analysis of Persistent Diabetic Macular Edema: Integrating Aqueous Humour Metabolomics, Clinical and OCT Features

ABSTRACT Purpose This exploratory study integrates aqueous humour metabolomic data with clinical and imaging features to examine candidate biomarkers and characterize multimodal patterns associated with persistent diabetic macular edema (pDME). Methods In this prospective cohort...

Desire, judgment, and burdened agency: Female knight-errant subjectivity and production formation in three contemporary Chinese Wuxia films

This article contributes to feminist wuxia studies by asking how contemporary Chinese wuxia films make women legible not only as fighters but as ethical subjects. Comparing Ang Lee’s Crouching Tiger, Hidden Dragon (2000), Hou Hsiao-hsien’s The Assassin (2015), and Yuen Woo-ping’s...

NINJ2 alleviates inflammatory bowel disease by regulating the macrophage ZBP1-PANoptosis pathway

Abstract Inflammatory bowel disease (IBD) is a chronic, relapsing intestinal disorder with a complex etiology and incompletely understood pathogenesis, posing significant challenges for clinical management. The NINJ2 gene is located on chromosome 12, a region enriched with IBD su...

When needs exceed systems: a mixed-methods study of clinicians’ perceptions of supportive care for older patients in emergency departments

Older adults presenting to emergency departments (EDs) have complex and multidimensional care needs that extend beyond acute illness management. This study examined clinicians’ perceptions of older patients’ supportive care needs and available system support and explored how clin...

Central and bridge nodes in depression, anxiety, and resilience networks across adolescent latent profiles: a latent profile and network analysis

Resilience is closely associated with adolescent mental health, but patterns of its co-occurrence with depression and anxiety symptoms remain unclear. This study combined latent profile analysis (LPA) and network analysis to characterize symptom-resilience profiles and examine ne...

Rimegepant for vestibular and cochlear symptoms associated with vertigo in a real-world retrospective study

Vertigo commonly co-occurs with cochlear symptoms, yet evidence for calcitonin gene-related peptide (CGRP) receptor antagonists across audiovestibular disorders remains limited. We retrospectively evaluated 54 adults with vertigo who received rimegepant 75 mg daily or every other...

Passive Metasurface Tweezers for Multi‐Scale Orbital Transport and Trapping on Elastic Plates

ABSTRACT Acoustic manipulation on solid surfacesis often constrained by limited wave‐field reconfigurability and reliance on complex active excitation, hindering the simultaneous realization of particle confinement and controlled rotation. Here, we present a passive, subwavelengt...

Genotype-phenotype correlations in HNF1B-associated disease: a systematic review

Multiple organ systems can be affected by pathogenic variants in the HNF1B gene, with renal phenotype usually being the initial presentation. However, the genotype-phenotype correlations in HNF1B -associated disease remain unclear. To further explore the genotype-phenotype correl...

Factors influencing healthcare providers’ adoption of artificial intelligence-based clinical decision-support systems: a systematic review using the CFIR framework

Artificial intelligence-based clinical decision-support systems (AI–CDSS) are increasingly used in healthcare, but their adoption by healthcare providers (HCPs) remains challenging. Reported determinants span technological, organizational, individual, and implementation-related l...

Preparation of Bisfuran-Based Biopolythioureas via Multicomponent Polymerization and Its Performances as Biosorbent for Hg2+ Removal

Abstract Utilizing agro-industrial wastes/byproducts as feedstocks for functional polymers offers a promising approach to alleviating urgent resource shortages. Herein, elemental sulfur (an oil-refining byproduct) and renewable diisocyanide/diamine (agrowate derivatives) were emp...

Clinical outcomes of combined hepatic arterial infusion chemotherapy with targeted or immunotherapy in advanced hepatocellular carcinoma

This retrospective study aimed to evaluate the efficacy and safety of combining hepatic arterial infusion chemotherapy (HAIC) with tyrosine kinase inhibitors (TKIs) or immune checkpoint inhibitors (ICIs) versus HAIC alone for the treatment of advanced hepatocellular carcinoma (HC...

Impact of ideal scaling on BEPU uncertainty and sensitivity analysis of the ACME test facility

In applications of the BEPU approach, uncertainty analyses are typically performed only at the test facility or the reactor, and the impact of model scale on uncertainty quantification remains an open issue to be further investigated. As a first step toward addressing this issue,...

Star formation powers optical line emission from the CGM

Using integral field spectroscopy, we explore the disk-halo interface, or the inner circumgalactic medium (CGM), of individual galaxies by constructing and analyzing emission-line maps for a large sample (72) of normal, low-redshift galaxies spanning three orders of magnitude in...

Elevation Amplifies Carrier-Type Differences in Nitrogen Cycling and N 2 O Dynamics in Lake Biofilms

Abstract Lake biofilms are microbial habitats for nitrogen transformation, but how carrier type and elevation influence N2O dynamics remains unclear. We examined abiotic- and biotic-carrier biofilms from 12 lakes spanning 4–4272 m using anoxic incubations, 15N tracing, selective...

Simultaneous Inhibition of PARP-1 and CK2α by Novel Benzothieno[3,2- d ]pyrimidin-4(1 H )-one Derivatives: A Promising Strategy to Combat Homologous Recombination Deficiency-Independent Tumors and Metastasis

Abstract Poly(ADP-ribose) polymerase 1 (PARP-1) inhibitors yield robust clinical benefits yet only work for homologous recombination deficiency (HRD) patients. To expand their utility and resolve clinical drawbacks, we synthesized dual PARP-1/casein kinase II alpha (CK2α) inhibit...