Fujian Medical University

Multimodal fusion of radiomics, dosiomics and deep learning for predicting radiation-induced hypothyroidism after radiotherapy in nasopharyngeal carcinoma: a multicenter study

To develop and externally validate a prediction framework integrating clinical factors, dose‒volume histogram (DVH) parameters, radiomics, dosiomics and deep - learning (DL) features for individualised radiation-induced hypothyroidism (RIHT) risk assessment. This retrospective mu...

P1.167. The Learning Curve of the Thoracic Phase in Single-Port Thoracoscopic Esophagectomy for Esophageal Cancer

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background Single-port thoracoscopic esophagectomy is an emerging minimally invasive technique that offers potential advantages in reducing surgical trauma and accelerating postoperative recovery. However,...

P1.165. Low Preoperative Fat-Free Mass Index Predicts Anastomotic Leakage and Poor Survival in Esophageal Cancer

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – long term outcomes Background Esophageal cancer is one of the most common gastrointestinal malignancies worldwide. In China, most patients are diagnosed at intermediate and advanced stages, and the treatm...

Optimizing Vanadium Single‐Atom Nanozyme via Cluster‐Mediated Charge Orchestration for Modulating Immune Homeostasis in Intracerebral Hemorrhage

ABSTRACT Intracerebral hemorrhage (ICH) triggers excessive reactive oxygen species (ROS) accumulation and persistent neuroinflammation, which synergistically drive progressive neuronal damage and poor neurological functional recovery, severely restricting patient prognosis. Artif...

Global and regional brain-age gaps in primary trigeminal neuralgia: a cross-sectional structural MRI study of 133 anatomical structures

Primary trigeminal neuralgia (TN) is a severe craniofacial neuropathic pain disorder. Quantitative magnetic resonance imaging (MRI) studies suggest that TN-related alterations may extend beyond the trigeminal pathways. The brain-age gap (BAG) is MRI-predicted brain age minus chro...

Role of intermittent hypoxia in the dysregulation of serum uric acid levels in non-obese adults with obstructive sleep apnea syndrome

This study investigated the association between serum uric acid (SUA) and obstructive sleep apnea syndrome (OSAS) and identified risk factors for elevated SUA in non-obese patients. Consecutive non-obese patients referred to the sleep center for suspected OSAS were included. Corr...

P1.164. Clinical Outcomes of Esophageal Bypass Surgery in Patients With Advanced Esophageal Cancer: A Single-Center Study

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – technique Background Esophageal bypass surgery is a therapeutic approach for patients with unresectable esophageal cancer who cannot eat orally due to esophageal stricture. It is particularly indicated fo...

Computational Oncology of Chemotaxis-Driven Tumour–Immune Spatial Patterning and Stability

We develop a reaction–diffusion–chemotaxis model for spatial tumour–immune–chemokine dynamics that couples logistic tumour growth, immune-mediated killing, chemokine-dependent immune recruitment, chemotactic migration, and signal production. For the non-dimensional system, we est...

MTAP deficiency in lung cancer cells enhances proliferation and migration and increases vulnerability to bone metastasis

Lung cancer continues to be the leading cause of cancer-related death worldwide. The advent of molecular targeted therapies has significantly changed the treatment landscape. Therefore, identifying new molecular targets is essential for the development of more effective treatment...

Research engagement profiles among Chinese undergraduate and postgraduate students

Research engagement is increasingly recognized as an important component of student development in higher education, particularly in medical and health sciences disciplines, but it is often measured through isolated activities or publication status alone. This study examined rese...

Vibratory Characteristics and Quantitative Parameters of Laryngeal Dystonia: A Scoping Review of High‐Speed Videoendoscopy Studies

ABSTRACT Objective To review the clinical application and quantitative parameters of high‐speed videoendoscopy (HSV) in evaluating vocal fold kinematics in patients with laryngeal dystonia (LD), to summarize the limitations of existing studies, and to provide a reference for futu...

Tetrahedral DNA nanostructure–gated solution-phase CRISPR/Cas12a system for probe immobilization-free, reagent-efficient, and dual-phase electrochemical detection of circulating microRNAs in liquid biopsy

Liquid-biopsy nucleic acid biomarkers hold strong promise for non-invasive cancer diagnostics, yet their ultralow abundance presents substantial analytical challenges. Conventional electrochemical biosensors rely on complex probe immobilization, whereas emerging homogeneous strat...

Ultrathin 2D Multivariate Hydrogen‐Bonded Organic Framework Nanosheets for Fluorescent DNA Sensing

The multivariate strategy is generally incompatible with densely packed structures, as this approach typically requires porous frameworks to manage the steric demands of incorporated functional groups. Without sufficient free volume, the frameworks are prone to structural transfo...

Five-year surveillance of pediatric respiratory pathogens in Fuzhou (2019–2024): impact of the COVID-19 pandemic

This study aims to investigate the epidemiological characteristics and distribution patterns of respiratory pathogens in children in Fuzhou between 2019 and 2024, with a particular focus on changes associated with the COVID-19 pandemic. This retrospective study included children...

Risk factors and prevalence of incontinence-associated dermatitis in elderly patients: a meta-analysis and systematic review

This systematic review aimed to evaluate the prevalence and risk factors of Incontinence-Associated Dermatitis (IAD) in elderly patients. A systematic search was conducted across 10 databases, including PubMed, Embase, Web of Science, Cochrane Library, CINAHL, Ovid MEDLINE, Scopu...

CACA guidelines for the management of adult cancer pain

Abstract Cancer pain, one of the most prevalent and distressing symptoms in cancer patients, is closely associated with cancer diagnosis, therapeutic interventions, quality of life, and survival outcomes. Effective cancer pain management requires multidisciplinary collaborative a...

Mefatinib versus gefitinib as a first-line treatment for EGFR-mutated non-small cell lung cancer: a randomized, double-blind, multicenter phase III study

Mefatinib, a novel second-generation epidermal growth factor (EGFR) tyrosine kinase inhibitor that has shown promising antitumor activity in targeting non-small cell lung cancer (NSCLC) with common and uncommon EGFR- activating mutations. In this phase III, randomized, double-bli...

Nuciferine-Loaded Lipid Nanoparticle Microneedles Alleviate Intervertebral Disc Degeneration by Restoring Nucleus Pulposus Cell Homeostasis

Background/Objectives: Intervertebral disc degeneration (IDD) is a major cause of chronic low back pain and disability. Nuciferine, a natural alkaloid with mitochondrial protective activity, shows therapeutic potential for IDD. However, the avascular nature of intervertebral disc...

Association between cardiometabolic index and incident electrocardiographic abnormalities in older adults

Electrocardiographic (ECG) abnormalities are important predictors of cardiovascular events in older adults, yet their early identification remains challenging. The cardiometabolic index (CMI), which integrates central obesity and lipid metabolism, has emerged as a potential marke...

Comparative efficacy of irrigation activation systems in root canal cleanliness: a region-specific analysis of debris and smear layer removal

This study aimed to compare the efficacy of four irrigation activation systems against conventional needle irrigation (CNI) in removing debris and smear layer from root canal. Forty human single-rooted teeth premolars were instrumented to a consistent size and randomly divided in...