Fudan University

Interface-shrunk regulated synthesis of asymmetric ultrafine mono-mesopore Nepenthes with tailored window

Asymmetric ultrafine mono-mesopore architectures with ultrasmall size, an open window, and unique physicochemical properties offer great opportunities in energy storage, yet their synthesis remains challenging. Inspired by the fast, unidirectional capture ability of Nepenthes, we...

Sensitive andReproducible SERS Profiling of Tumor-DerivedEVs via Uniform Microfluidic Nanobowl Arrays for Pancreatic CancerManagement

Abstract Tumor-derived extracellular vesicles (EVs) are promising liquid biopsy biomarkers, yet their clinical translation is hindered by the trade-off between enhancement and reproducibility of SERS-based detection. Here, we present a microfluidic SERS platform integrating plasm...

Targeted biologics in muscle strength restoration and corticosteroid sparing for patients post-myasthenic crisis

Myasthenic crisis (MC) represents a life-threatening condition in patients with myasthenia gravis (MG). Despite a substantial reduction in in-hospital mortality for MC, full restoration of muscle strength and quality of life usually requires months or years. It remains unknown wh...

Blue Light Pollution and Ocular Surface Toxicity: p53-Mediated Ferroptosis in Corneal Epithelium Drives Dry Eye Pathogenesis

Purpose: This study investigated the molecular mechanisms underlying blue light-induced corneal epithelial toxicity. Methods: C57BL/6J mice were exposed to 460 nm blue light for 1, 2, or 4 weeks, whereas human corneal epithelial (HCE) cells were exposed for 15 or 30 min. RNA-sequ...

Empowering PolymericMaterials Discovery by ArtificialIntelligence

Abstract Polymeric materials underpin modern technologies spanning energy storage, microelectronics, healthcare and sustainable manufacturing. Yet their rational design remains exceptionally challenging because material performance emerges from complex interactions among molecula...

Building a Physics-Aware AI Ecosystem for Solid-State Hydrogen Storage Materials

Abstract Hydrogen storage remains a central bottleneck for scalable hydrogen energy systems due to the multiscale and coupled nature of the thermodynamics, kinetics, and microstructural evolution of hydrogen storage materials (HSMs). Although artificial intelligence (AI) has acce...

Mechanism and plasticity of primitive pyroptosis

Pyroptosis is a proinflammatory form of regulated cell death across the tree of life. The gasdermin (GSDM) protein family functions as an evolutionarily conserved executioner of pyroptotic cell death by forming membrane pores. As the canonical activation mechanism, proteolytic cl...

Effects of a neuromuscular warm-up on Y-balance, countermovement jump performance, and stroke velocity in adolescent table tennis players

Background/Objective Adolescent table tennis players are exposed to substantial physical and psychological demands during a period of ongoing growth and development, placing high demands on movement control, explosive performance, and sport-specific stroke execution. This study i...

Symmetry-DependentUltrafast Spin Currents and THzEmissions in Noncollinear Antiferromagnetic Mn3Pt/Pt Heterostructures

Abstract Noncollinear antiferromagnets (NCAFs) provide a symmetry-rich platform for ultrafast spintronics, where light-driven spin currents are governed by both crystallographic orientation and magnetic symmetry. Here, we investigate femtosecond-laser-induced terahertz (THz) emis...

Influence of many-body correlation and mixed-valence fluctuations on X-ray magnetic circular dichroism and resonant inelastic X-ray scattering spectra

X-ray magnetic circular dichroism (XMCD) and resonant inelastic X-ray scattering with magnetic circular dichroism (RIXS-MCD) provide unparalleled insights into the electronic and magnetic dynamics of complex materials. However, interpreting their spectra in mixed-valence systems...

MultidimensionalQuantitative Analysis of BiologicalResponses to DNA Nanoassemblies with Defined Structure and SurfaceChemistry

Abstract DNA nanoassemblies (DNs) have emerged as programmable platforms for biomedical applications; however, a quantitative understanding of how structure and surface chemistry jointly govern their biological behavior remains limited. Here, we establish a multidimensional analy...

Hydrogel-EmpoweredInterfacial Reactive Hydrogen onCopper Enables Selective Nitrate-To-Ammonia Electrocatalysis

Abstract Precise control of interfacial reactive hydrogen is crucial for improving the selectivity of proton-coupled electron transfer reactions in electrocatalysis. In the nitrate electroreduction to ammonia reaction, a fundamental trade-off is identified for copper (Cu)-based c...

The efficacy of stem cell therapy: cells or their microenvironment?

The therapeutic outcomes of stem cell therapy are determined not solely by cellular potency alone, but also by the receptiveness of the host microenvironment. Despite continuous progress in stem cell quality control and functional optimization technologies, inconsistent outcomes...

Star PolyelectrolyteCoacervates Enable Adaptive andRobust Enzyme Immobilization for Efficient Biocatalysis

Abstract Enzyme immobilization in solid porous supports often suffers from a trade-off among enzyme loading, mass transport, catalytic activity, and operational stability. Here, we report a liquid-like immobilization platform based on star polyelectrolyte coacervates (SPECs) form...

Thermodynamic characteristics of a twisted oval tube with dimples at varying positions

To further enhance the thermal performance of twisted oval tubes, this paper innovatively installs dimples at different positions on the cross-section of twisted oval tubes and investigates how the dimple position affects the flow and heat transfer characteristics in these tubes....

Two-wave modified cardiometabolic index change patterns and incident edentulism in Chinese adults: a longitudinal study from CHARLS

Abstract Objectives Complete tooth loss is a late-stage oral health endpoint that may reflect cumulative oral, systemic, behavioral, and social risk processes. We examined whether two-wave patterns of the modified cardiometabolic index (MCMI) from 2011 to 2015 were associated wit...

On the Schubert calculus of the quantum K-theory for partial flag manifolds: a 3d A-model perspective

A bstract We further investigate the 3d gauged linear sigma model (GLSM)/ quantum K-theory correspondence for partial flag manifolds X ≡ Fl( k ; n ). This is a 3d uplift of the 2d GLSM/quantum cohomology correspondence with the 3d theory compactified on $$ {\mathbb{R}}^2\times {S...

Identifying the interactive pathways shaping health satisfaction among Chinese older adults with tourism participation

As global aging accelerates, improving older adults’ health satisfaction is a key policy and public health concern. While tourism has been associated with well-being, the pathways through which it is associated with health satisfaction remain unclear. It is not well understood wh...

Rapid general electromagnetic analysis of metallic surfaces via conformal energy minimization

We recently found that the electromagnetic scattering problem can be solved efficiently using an approach that expresses the fields in terms of a set of orthonormal basis functions. In this paper, we apply computational conformal geometry with the conformal energy minimization (C...

Influence of Water Molecule Adsorption and H2 ReductionTreatment on Acid Sites of WO3 with the (002)Crystal Facet Studied by Solid-State NMR Spectroscopy

Abstract In-depth investigations of the influence of water molecule adsorption and H2 reduction treatment on surface acid sites of metal oxides are vital to elucidate the mechanism of catalytic reaction and to optimize the design of catalysts. By introduction of different amounts...