Centre National de la Recherche Scientifique

Human pressure, habitat heterogeneity and species traits jointly determine the level of dark diversity in coastal fish communities

Understanding how anthropogenic pressures and environmental gradients shape coastal fish communities is a central question in biogeography and marine conservation. Yet, the set of species expected to occur at a site given ecological conditions but being absent – the so‐called dar...

An inertial‐based spiral device for separating rare tumor cells from liquid biopsies

Abstract Early detection of primary tumors and metastatic processes increases the success of anti‐tumor therapies and favors good prognoses. Within the current range of methods available to detect the presence of tumors, liquid biopsy is receiving particular attention as it is a...

Sterile Insect Technique in a n-patch System with Allee Effect and Mass Trapping: Modelling, Analysis and Simulations

Abstract The sterile insect technique (SIT) is a biological control method aimed at reducing or eliminating populations of pests and disease vectors. This technique involves releasing sterilised insects which, by mating with wild individuals, will reduce the target population. In...

A refined Saccharomyces cerevisiae reference transcriptome from Direct RNA Sequencing, with a reusable pipeline for UTR annotation updates

Untranslated regions (UTRs) flanking the coding sequence govern mRNA translation, localisation, and decay, making accurate UTR boundaries essential for quantitative RNA sequencing and the study of post-transcriptional control. Reference transcriptomes built from short-read sequen...

The influence of force on the encoding and perception of affective touch

Abstract Stroking touch has been shown to be most pleasant at intermediate velocities of 1-10 cm.s −1 , which relates well to the activity of C-low threshold mechanoreceptors (C-LTMRs), also called C-tactile afferents in humans, that have been implicated in encoding positive affe...

Designing Accessible Interfaces to Enhance Collective Musical Engagement for and with Children with Autism

Accessible Digital Musical Interfaces (ADMIs) aim to enhance the inclusivity of musical practice by supporting users with diverse needs. This paper focuses on the design and use of ADMIs for and with autistic children. While previous research has highlighted the developmental ben...

The elongation of Mest transcript into MestXL sustains, but does not initiate, the maternal allele bias of its convergent gene Copg2 during neurogenesis

Abstract Precise gene dosage control is critical for cellular identity and development, particularly for imprinted genes, where dosage imbalances are linked to neurodevelopmental disorders. The Mest/Copg2 imprinted locus exemplifies this fine-tuned regulation: while Mest is const...

High-Dimensional Analysis of Ridge Regression for Non-identically Distributed Data with a Variance Profile

Abstract. High-dimensional linear regression has been thoroughly studied in the context of independent and identically distributed data. We propose to investigate high-dimensional regression models for independent but non-identically distributed data. To this end, we suppose that...

Toward More Predictable Musculoskeletal Embolization: A Translational Evaluation of Imipenem–Cilastatin Performance and Safety in a Porcine Model of Tendon Neovascularization

Background: There is a need to provide a translational evaluation of imipenem–cilastatin as an innovative musculoskeletal embolic agent by assessing its embolization efficacy, physicochemical behavior, and safety profile in a porcine model of intratendinous neovascularization. Ma...

Wet granular bed eroded by a dry granular flow

Using three-dimensional discrete element method simulations, we investigate the erosion dynamics of a cohesive bed composed of wet spherical particles subjected to the shear flow of an overlying noncohesive granular layer. Cohesion is modeled through a capillary attraction law, w...

Characteristic cycle and wild Lefschetz theorems

Abstract By relying on a new approach to Lefschetz type questions based on Beilinson’s singular support and Saito’s characteristic cycle, we prove an instance of the wild Lefschetz theorem envisioned by Deligne. Our main tool are new finiteness results for the characteristic cycl...

Synergism Between Krameria lappacea (Dombey) Burdet & B.B.Simpson Extracts and Gentamicin Against Gram-Positive Bacteria

Background: Combination therapy is increasingly explored as an alternative approach to manage bacterial infections and limit the emergence of antibiotic resistance. Building on traditional medicinal knowledge, this study aimed to investigate the potential synergistic antibacteria...

Craniometric evaluation of population affinity among South African subadults

Although standard craniometrics is typically regarded as the method of choice for estimating population affinity in adults, its application to subadults has received limited attention, despite potential population-specific signals demonstrated in cranial growth patterns. This stu...

Surface Plasmons in the Continuum

Abstract The interest to foster plasmonic applications at energies in the ultraviolet has escalated research initiatives in clusters of unconventional plasmonic materials like aluminum and indium, for which the surface-plasmon resonance appears above the ionization potential. Nat...

Maximum Number of Requests on a Path With a Given Grooming Factor

ABSTRACT We give an optimal solution to the Maximum All Request Path Grooming (MARPG) problem motivated by a traffic grooming application and by its interest in computing lower bounds on the cutwidth of a graph. We are given a directed path on vertices and a positive integer capa...

Evolutionary dynamics and functional refinement of IGF bioavailability in the vertebrate phylum : focus on IGFBPs

In eutherians, Insulin-like Growth Factor-I (IGF-I) and IGF-II exert insulin-like activity by interacting with type-I receptor. IGF bioavailability is finely regulated by six IGF-Binding Proteins (IGFBPs), IGFBP-1 to -6, which bind IGF-I and -II with high affinity but not insulin...

Frequency-dependent shear and bulk viscosity of aqueous and non-aqueous lithium battery electrolytes

Transverse ultrasound was used to examine the frequency-dependent shear viscosities of three lithium bis(trifluoromethanesulfonyl)imide-based electrolytes: aqueous, non-aqueous, and hybrid aqueous-organic solutions. Frequency-dependent bulk viscosities of two of the electrolytes...

Probing near-surface potentials with the self-binding threshold of dipolar quantum droplets

Abstract Self-bound quantum droplets formed by strongly magnetic atoms are a platform for quantum metrology experiments. Here, we form a theoretical framework wherein external potentials generated in the interior of a hollow cylinder can be observed via modification of the format...

Atenolol or Bisoprolol after Myocardial Infarction without Recorded Heart Failure

BACKGROUND: Beta-blockers are a cornerstone of therapy following myocardial infarction. The effect of different β-blockers on the outcomes of patients without heart failure after myocardial infarction is not well-studied. METHODS: This observational cohort study used administrati...

The spinorial ball (II): A manipulable qubit at human scale

The spinorial ball is an interactive electronic device that we recently introduced to discuss the origin of spin-1/2 from the representation of the rotation group, without the framework quantum mechanics. Nevertheless, it can also be viewed as a macroscopic visualization of a qua...