Centre National de la Recherche Scientifique

Optimizing the Ocular Surface Before, During, and After Glaucoma Surgery: A Narrative Review

This narrative review synthesizes the published literature on ocular surface disease (OSD) and glaucoma filtration surgery to develop practical, evidence-informed clinical and surgical recommendations for optimizing ocular surface management before, during, and after surgery. The...

A memory of Paleozoic to Quaternary Greenhouse climates recorded in Southern African regolith

Abstract In this article, we explore the potential of iron-rich duricrust regoliths from old erosional anorogenic surfaces to record clues of the long-term continental paleoclimatic evolution. We coupled geochemical, mineralogical and geochronological analyses on iron oxides and...

Low intensity transcranial electrical stimulation for schizophrenia: a triple-blind, randomized, sham-controlled multicenter trial (STIM’Zo)

Persistent symptoms in schizophrenia remain a major therapeutic challenge. Noninvasive electrical stimulation such as transcranial random noise stimulation (tRNS) may alleviate auditory hallucinations and negative symptoms, although existing evidence is limited to case reports an...

On the use of seismic noise studies for landslide rock block hazard assessment

As emphasized by Pazzi et al. 1 , robust constraints on rock-mass volume are essential for landslide hazard assessment. However, such estimates are inherently challenging due to (i) complex geometries, (ii) heterogeneous material properties, and (iii) poorly constrained boundary...

On Hyperbolic Approximations for a Class of Dispersive and Diffusive-Dispersive Equations

Abstract We introduce novel approximate systems for dispersive and diffusive-dispersive equations with nonlinear fluxes. For purely dispersive equations, we construct a first-order, strictly hyperbolic approximation. Local well-posedness of smooth solutions is achieved by constru...

Sex-related variability of white-matter tracts is robust to tractography methodology

Abstract Diffusion tractography is the prominent in-vivo technique to study and investigate white-matter pathways in the human brain. While tractography is a powerful method, recent work suggests that different tractography methods can produce strikingly different representations...

A predictive coding framework for safe and versatile control of supernumerary robotic limbs

Supernumerary robotic limbs (SLs) have the potential to extend human sensorimotor capabilities by increasing effective degrees of freedom. However, current systems are designed for a single task and cannot flexibly coordinate with natural limbs (NLs). Here we propose a hierarchic...

Molecular mechanisms of supercritical CO2-induced interfacial softening in curcumin polymorphs

Unique properties of supercritical CO 2 (scCO 2 ) make it one of the most interesting “green” solvents for pharmaceutical particle formation and polymorph engineering. However, due to the complexity of the scCO 2 dynamics, the molecular mechanisms by which scCO 2 alters the stabi...

Anti-thymocyte globulin triggers TNF-dependent cell death in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) accounts for one of the most aggressive hematological tumors associated with poor prognosis, notably for relapsed and refractory patients. Hence, an unmet medical need persists for T-ALL patients who fail to durably respond to conventio...

A review on catalyst deactivation in the oxidative desulfurization process: Causes and mitigation strategies

In recent years, oxidative desulfurization (ODS) has gained significant attention as a promising solution for removing sulfur compounds from fuel oils, particularly heavy marine fuels, to comply with increasingly stringent environmental regulations. While most ODS studies focus o...

Learning-Based Methods and the Future of Numerical Ocean and Sea-Ice Modeling

The field of operational oceanography is undergoing a significant evolution with the increasing integration of artificial intelligence (AI) methods, which are complementing and, in some cases, redefining traditional numerical modeling approaches. This review explores how AI metho...

Tracking the Mechanism of Electrocatalytic Hydrodeoxygenation of Propylguaiacol by Electrochemical Membrane-Inlet Mass Spectrometry

Abstract Lignocellulose-derived bio-oils require hydrodeoxygenation (HDO) to reduce their oxygen content for integration into conventional fuels. Electrocatalytic HDO (eHDO) offers a sustainable alternative to traditional high-temperature, high-pressure processes, but its mechani...

Extrinsic Limitations of Stealthy Hyperuniform Devices

ABSTRACT Hyperuniformity promises an unusual form of wave control: the suppression of elastic scattering over extended angular ranges without periodic order. Here, we present a comprehensive experimental and theoretical study of 2D stealthy hyperuniform metasurfaces operating at...

When Participation Becomes a Criterion: Developing an Analytical Framework for Participatory Science

Participatory science projects have multiplied in recent years, yet frameworks to analyse and evaluate them remain fragmented. While conventional research relies on standardized criteria, participatory research requires approaches that account for collaborative processes, governa...

Introducing shrubs enhances the representation of high-latitude vegetation and carbon cycling in the ORCHIDEE land surface model

Arctic–Boreal terrestrial ecosystems are rapidly changing under amplified high-latitude warming, including widespread expansion of shrubs, with consequences for regional carbon and energy balances. Yet, high-latitude vegetation diversity and vegetation–climate interactions remain...

Extending the ATP9A ‐Related Phenotypic Spectrum: Indication of Schizophrenia Susceptibility

ABSTRACT ATP9A, which belongs to the P4‐ATPase family of proteins, is involved in the efficient transport of vesicles from the Golgi apparatus to the plasma membrane, as well as the release of extracellular vesicles from human cells. In 2021, a loss‐of‐function variant of this ge...

Neurotoxicity and cognitive outcomes in modern therapies for primary central nervous system lymphoma

PURPOSE OF REVIEW: Improved survival in primary CNS lymphoma (PCNSL) has increased the importance of delayed treatment-related neurotoxicity as a determinant of functional outcome and quality of life. This review summarizes contemporary evidence on neurocognitive outcomes across...

Coordinated resistance–virulence organization across urban microbiomes reveals context-dependent ecological structuring

Microbial communities in built environments are shaped by functional traits associated with persistence, ecological interaction, and pathogenic potential. While antimicrobial resistance (AMR) genes and virulence factors (VFs) are typically studied independently, their coordinated...

Observation-constrained clear-sky direct radiative forcing of black carbon containing aerosols reveals distinct radiative regimes across urban Asia

Black carbon (BC) aerosols exert a strong yet uncertain influence on the atmospheric energy balance, yet their radiative forcing estimates remain poorly constrained. Current top-down and bottom-up approaches remain limited in resolving how microphysical evolution and column prope...

Distinct migratory dendritic cell subsets cooperate to prime tissue-resident memory-like CD8⁺ T cells in mouse tumors

Tumor-infiltrating tissue-resident memory (TRM)-like CD8+ T cells correlate with positive prognosis and better responses to cancer immunotherapy, yet the mechanisms underlying their specification remain ill-understood. Here, we use the KP (KrasG12D, p53-/-) mouse model of lung ad...