The study used ensemble simulations with the GISS and CESM global climate models to examine the combined effects of reducing reactive nitrogen pollution. By mid-century, both models projected lower global concentrations of fine particles and ground-level ozone, although the size of the changes differed between models.

The simulations also indicated that more than 80% of avoided premature deaths would occur between 0 and 60 degrees north latitude. Nitrogen management produced a modest, temporary near-term climate penalty, but reduced nitrous oxide emissions eventually outweighed that effect, producing longer-term climate, health and ecosystem co-benefits.