Shandong University

Astronomical spectra as language: Order-agnostic foundation model for low-SNR reconstruction and stellar parameter prediction

Large-scale spectroscopic surveys contain numerous low-SNR stellar spectra that are difficult to analyze with traditional pipelines but remain valuable for Galactic archaeology, chemical-evolution studies, and population-level stellar characterization. We propose an order-agnosti...

Early-life recurrent antibiotic use and risks of adult kidney cancer and sex-specific cancers: a prospective cohort study in the UK Biobank

There is little evidence about the associations of long-term or recurrent antibiotics use (LRAU) during early life with cancer risk. Our study aimed to assess the associations via Cox proportional hazards regression, using data from the UK Biobank (UKB). The main outcomes were th...

Emergence of novel SARS-CoV-2 variants keeps slowing down

Abstract Background Although COVID-19 pandemic has no longer been classified as an international public health emergency of concern after May 2023, multiple variants with different characteristics keep emerging. Given the complex spatial-temporal characteristics of epidemics, res...

Translating and reframing of the narratives of “Fó” (佛) in Journey to the West: a case study on Lovell’s translation

Abstract This study examines British sinologist Julia Lovell’s abridged English translation of Journey to the West , focusing on how narratives of “佛” ( Fó , Buddhas) are translated and reframed through socio-narrative theory. It argues that Lovell’s translation substantially di...

Low-dose interval radiotherapy combined with tirelizumab and SOX chemotherapy neoadjuvant therapy for locally advanced gastric/gastroesophageal junction adenocarcinoma: study protocol of a prospective, single-center, single-arm clinical trial

Abstract Background：Gastroesophageal junction (G/GEJ) cancer is a global health burden with poor prognosis, especially for locally advanced or metastatic cases. While perioperative chemotherapy improves outcomes, survival remains limited. Immunotherapy combined with chemotherapy...

Ferroptosis-Regulated Osteoblasts Under Compression Via GPX4/RUNX1 Pathway

Background: The adaptive remodeling of alveolar bone ensures the effectiveness and stability of orthodontic tooth movement (OTM), but how to accurately regulate the remodeling of alveolar bone is the focus of orthodontic research. Ferroptosis plays an important role in bone remod...

Prediction and Progression Stratification of Type II Endoleak After EVAR Using Clinical, Anatomical, and Ultrasound Parameters

OBJECTIVE: To identify factors associated with type II endoleak (T2EL) after endovascular aneurysm repair (EVAR) and to stratify sac progression risk in patients with established T2EL using clinical, anatomic, and ultrasound-derived parameters. METHODS: This ambispective cohort s...

Ambient‐Processed Organic Solar Cells Achieving Nearly 20.5% Efficiency and Industrially Viable Environmental Stability

The ability to process organic solar cells (OSCs) in ambient air is a critical prerequisite for industrial-scale production, as it obviates the need for a high-cost inert atmosphere. However, state-of-the-art cathode interlayers (CILs) typically require strongly hydrophilic group...

TaIAA25 negatively regulates wheat alkaline tolerance by inhibiting plasma membrane H + -ATPase activity

Soil salinization/alkalization represents a universal challenge that severely constrains crop productivity. Elucidating the molecular mechanisms underpinning saline/alkaline tolerance of wheat ( Triticum aestivum ) holds profound significance for global food security and sustaina...

Optimization of Geometric Parameters in Moon Texturing to Enhance the Tribological Performance of AISI 5115 Steel

Abstract Surface texturing can significantly enhance the tribological performance of materials. In this study, a novel moon-shaped surface texture was designed and optimized via computational fluid dynamics (CFD) simulations. The optimal geometric parameters were identified as R...

DualPop: User Popularity Preference Aware Debiasing Recommendation

Recommender systems usually suffer from popularity biases, where a few popular items are over-recommended, while most long-tail items struggle to gain exposure. Prior research focused on eliminating the influence of popularity to suppress popular items and enhance the recommendat...

Controllable Growthof GaSb Nanowires Catalyzed byBi Films for Flexible Near-Infrared Photodetectors

Abstract With a direct narrow band gap and high hole mobility, the III–V group semiconductors of GaSb nanowire (NW) are considered as promising channel materials for next-generation high-performance nanoelectronics and infrared photodetectors. In this study, the complementary met...

Efficient nitrogen management as a win-win strategy for air quality, health, and climate

Reactive nitrogen (Nr) management links climate policy, air quality and food production, yet its combined impacts remain poorly quantified. Here, we conduct ensemble simulations with two global climate models, Goddard Institute for Space Studies (GISS) and Community Earth System...

A tumor-on-a-chip model reveals and targets reciprocal macrophage–NK cell crosstalk to advance immunotherapy screening

Effective cancer immunotherapy is hindered by immunosuppressive crosstalk within the tumor microenvironment. We engineered a tumor immune microenvironment-on-a-chip (TIMoC) that recapitulates the vascularized, hypoxic, and spatially organized niche of human solid liver tumors. We...

Reduced SRSF1 Expression Correlates with LCK Exon Skipping and Impaired Treg Induction in Immune Thrombocytopenia

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by antibody-mediated platelet destruction and impaired regulatory T-cell (Treg) function, yet its molecular basis remains poorly defined. Here, we show that CD4+ naive T cells from patients with ITP exhibit dim...

Aero-DETR: a frequency-adaptive sparse-interaction network for UAV-assisted aircraft surface defect detection

Abstract Aircraft surface defect inspection is critical for aviation safety but remains challenging because defects in unmanned aerial vehicle (UAV) imagery are often small, low-contrast, and multi-scale. We construct the aircraft UAV defect inspection dataset (AUDID), containing...

Simultaneous Determination of Total and Unbound Amphotericin B by LC–MS/MS: Application to Protein Binding Analysis

ABSTRACT Amphotericin B (AmB), a first‐line antifungal agent, is highly protein‐bound, and its efficacy and toxicity are primarily determined by the unbound fraction. However, current therapeutic drug monitoring mainly relies on total plasma concentrations, and clinical data on u...

Information Poverty Alleviation causing Implicit Information Poverty? Evidence from Rural Information Ecology in China

China’s targeted poverty reduction initiatives have expanded rural digital access, yet information-based interventions can also generate less visible forms of exclusion. This article examines how rural information ecology is shaped through information-driven poverty alleviation i...

A CombinedChemical Ionization and Photoelectron IonizationSource for TOFMS: Application to Online Detection of Aldehydes inEnd-Tidal Exhaled Breath

Abstract In conventional exhaled breath analysis, a CO2 sensor is typically deployed separately from a biomarker detection instrument. Herein, we developed an all-in-one ionization source that integrates chemical ionization (CI) and photoelectron ionization (PEI) within a single...

Programmable ZBTB7A RNA N6-methyladenosine site-specific demethylation suppresses colorectal cancer liver metastasis

Colorectal cancer liver metastasis (CRLM) is the primary cause of CRC-related mortality, with inevitable chemoresistance to targeted therapies and immunotherapy. N 6 -methyladenosine (m 6 A), as a crucial epigenetic regulator of gene expression and cellular physiology, involved i...