Xizang Minzu University

Metagenomic analysis of developmental-category-associated fungal communities in the gut contents of Achatina fulica, an intermediate host of Angiostrongylus cantonensis

The invasive giant African snail ( Achatina fulica ) poses serious agricultural and ecological threats and serves as an important intermediate host of the zoonotic parasite Angiostrongylus cantonensis , which causes human eosinophilic meningitis. While its gut bacterial microbiom...

PPARα Activation Attenuates Right Ventricular Hypertrophy by Regulating Myocardial Glucose and Lipid Metabolism in High-Altitude Pulmonary Hypertension In Vivo and In Vitro

Zhang, Xiaoying, Jiajia Wu, Yuchan Zhang, Yuquan Xie, Qi Si, Shadi Li, and Yiwei Han. PPARα activation attenuates right ventricular hypertrophy by regulating myocardial glucose and lipid metabolism in high-altitude pulmonary hypertension in vivo and in vitro . High Alt Med Biol....

Research progress on the interconnected network of mitophagy and energy metabolism in tumors

Abstract As hallmarks of tumors, mitophagy and energy metabolic reprogramming have drawn extensive research interest. Under acute stress, cells initiate mitophagy via ubiquitination-dependent or ubiquitination-independent pathways to maintain oxidative phosphorylation (OXPHOS) ef...

Ambient pressure and gas-liquid oxygen transfer at high altitude: A critical review of an uncorrected design assumption

Aeration is the most energy-intensive step in biological wastewater treatment, and is most constrained at high altitude, where low pressure and low temperature coincide. Standard design corrects the driving force for pressure by scaling the saturation dissolved oxygen C s , and c...

Dispersal-mediated coexistence and extinction dynamics in three archetypal food webs

Species dispersal is a fundamental process governing the spatial structure, stability, and persistence of ecological communities. While previous studies have elucidated the role of dispersal in simple food webs and omnivorous systems, a systematic comparison of how species-specif...

Functional niche partitioning influences species turnover across supraglacial microbial communities on the Longxiazai glacier, Tibetan Plateau

Glaciers represent unique ecosystems harboring diverse microbial communities that dominate biomass and drive biogeochemical cycling across supraglacial habitats. These microbes transform deposited modern and ancient carbon/nitrogen, and these elements are subsequently transferred...

Associations of altitude, physical activity, and body mass index with blood pressure components and grip strength in older adults with elevated blood pressure living at 3100–4500 m in Tibet: a cross-sectional study

High-altitude environments may influence cardiovascular and muscle function in older adults. We examined blood-pressure components and grip strength across three Tibetan altitude sites and their associations with residential altitude, physical activity, and body mass index (BMI)...

State of Health Estimation for Lithium-Ion Batteries in Energy Storage Systems: A Multi-Scale Spatiotemporal Deep Learning Approach

Accurate state of health (SOH) estimation of lithium-ion batteries is essential for ensuring the safe and efficient operation of electric transportation and grid-scale energy storage systems (ESS). However, extracting reliable degradation information from Battery Management Syste...

Synergy of surface oxygen vacancies and built-in electric field in 0D/2D CeO2/SnSe2 S-scheme heterojunctions for enhanced photocatalytic malachite green degradation

Abstract Industrial effluents exacerbate aqueous contamination, necessitating the urgent remediation of toxic dyes such as Malachite Green (MG). In this study, a 0D/2D S-scheme heterojunction was constructed by anchoring CeO 2 nanocubes onto SnSe 2 hexagonal nanosheets via a prec...

Efficient nitrogen management as a win-win strategy for air quality, health, and climate

Reactive nitrogen (Nr) management links climate policy, air quality and food production, yet its combined impacts remain poorly quantified. Here, we conduct ensemble simulations with two global climate models, Goddard Institute for Space Studies (GISS) and Community Earth System...

SLC3A2 identified as a new therapeutic target for head and neck squamous cell carcinoma

The head and neck squamous cell carcinomas (HNSCC), which is the most common malignant tumor of head and neck region. Programmed cell death pathways, including the ferroptosis pathway and the disulphide cell apoptotic pathway, have received increasing amounts of attention as pote...

Construction of a NAFLD identification model in Xizang population and exploration of risk factors related to liver fibrosis

The global prevalence of non-alcoholic fatty liver disease (NAFLD) exceeds 32%, but current diagnostic methods based on imaging or histology are complex and costly. Most existing NAFLD models are primarily derived from low-altitude populations, while the high-altitude populations...

Genetic diversity, haplotype structure, and population dynamics of Echinococcus granulosus isolates from human cystic echinococcosis in Tibet, China

Cystic echinococcosis (CE) is a globally important zoonotic disease caused by the larval (metacestode) stage of Echinococcus granulosus (sensu lato), a parasite complex characterized by marked genetic heterogeneity across geographical regions. The Tibet Autonomous Region (TAR) of...