Research works

Preparation of gold nanoparticles supported on microcrystalline cellulose by solid-mortar grinding and their catalytic activities

A solid-grinding approach for transforming microcrystalline cellulose into less ordered matrices, followed by the deposition of a high density of gold nanoparticles (NPs) without employing environmentally toxic chemicals, solvents, or external reducing agents is reported. The gen...

Ginsenoside Rg1Attenuates Neuroinflammation in Parkinson’sDisease Models via Concomitant Modulation of Canonical and NoncanonicalWnt Pathways in Microglial M1/M2 Polarization

Abstract Microglial-mediated neuroinflammation is a core driver of brain disorders. Thus, modulating microglial activity is a critical therapeutic goal. In this study, we explored how Ginsenoside Rg1 (Rg1) protects against the inflammation seen in Parkinson’s disease (PD). Our ex...

Developing a Multidisciplinary Model for Sexual Violence Response in Nigeria: Integrating Legal, Medical, and Social Perspectives

Sexual violence response in Nigeria remains fragmented despite growing legal recognition of sexual offenses and international advocacy for integrated, survivor-centered approaches. Existing interventions largely operate in institutional silos, limiting continuity of care and surv...

TrivalentAl Insertion into Layered-Oxide-DerivedPerovskite Oxynitrides for Defect-Controlled Dielectric Response

Abstract Al-containing perovskite oxynitrides, SrAl0.2M0.8O2.4N0.6 (M = Nb, Ta), were synthesized by ammonolysis of layered Sr5M4O15 precursors with α-Al2O3. This reaction demonstrates that the cation-insertion chemistry of layered-perovskite-derived oxynitrides can be extended t...

Unconventional BiocatalyticStrategies Orchestratethe Synthesis of the Nucleoside Analog Sinefungin

Abstract Sinefungin is a potent nucleoside antimetabolite of S-adenosylmethionine (SAM). Since its discovery in the 1970s, sinefungin has generated significant scientific interest owing to its role as a bioisostere of SAM and its broad range of biological activities. Despite cons...

The diagnostic and prognostic value of serum FBXO11 expression in neonatal sepsis

This study aimed to investigate the correlation between serum FBXO11 expression and serum PCT and CRP levels as well as its diagnostic and prognostic value in neonatal sepsis (NS). This study included 120 patients with NS aged ≤ 28 days, birth weight > 2500 g, and gestational age...

Preliminary experience of mechanical thrombectomy treatment in pediatric arterial ischemic stroke: a retrospective case series

To evaluate the feasibility and efficacy of mechanical thrombectomy in the treatment of pediatric acute ischemic stroke (AIS). The clinical data, radiographic results and management outcomes of children diagnosed with AIS and treated at our hospital between 2016 and 2021 were ret...

Analysing Lost Highway as a Non-deterministic Narrative Structure: Initiating Déjà Vu-like Recognition to Establish Non-causal Linkage

This article examines how repetition produces déjà vu-like recognition in non-deterministic narrative cinema. Focusing on David Lynch’s Lost Highway (1997), it argues that the film’s repetitions do not lead to conventional repetition–resolution, but instead organise an entangled...

Huang Ya’s Wisteria and the Cold War middlebrow: melodrama, Manichean worlds, and Mahua literature

As the longest-serving editor of the literary magazine Chao Foon, Malaysian Chinese (Mahua) writer Huang Ya (1932–1992) is widely regarded as a central figure in shaping Mahua modernism during the 1960s. Existing scholarship has largely focused on his editorial advocacy for Malay...

Psychiatric Adverse Events Associated with GLP-1 Receptor Agonists: Evidence of Intraclass Heterogeneity in the WHO VigiBase Global Database

Background/Objectives: Concerns regarding the psychiatric safety profile of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have increased since the 2023 European Medicines Agency (EMA) and U.S. Food and Drug Administration (FDA) reviews. However, it remains unclear whether...

A factor-based importance–satisfaction discrepancy approach for smart campus evaluation: evidence from comparative exploratory factor analyses

Abstract Smart campus evaluation commonly relies on descriptive satisfaction scores or importance-performance indicators, yet less is known about whether users organise satisfaction, perceived importance, and respondent-level importance–satisfaction discrepancies through equivale...

The Society for Women in Radiation Oncology Medical Physicists: Where Are We Five Years Later?

Background A better understanding of the personal experiences of women and gender minorities in medical physics is needed to ensure the vitality of the radiation oncology (RO) workforce. Founded in 2017, the Society for Women in Radiation Oncology (SWRO) sought to promote gender...

Comparing Provider Perspectives on Efficiency and Patient Safety With Paper and Digital Tools for Handoffs of Patient Care

OBJECTIVES: Handoffs of patient care are opportunities for promoting efficiency and safety. With the shift from paper to digital records, we examine changes in provider perceptions of efficiency, errors, and confidence on a labor and delivery service at an urban, academic hospita...

Clinicopathological Features, Tumor Localization and Treatment Outcomes in Paraganglioma: A Single-Center Medical Oncology Cohort

Background/Objectives: Paragangliomas (PGLs) are rare neuroendocrine tumors, and data describing them from a medical oncology perspective are limited. We characterized clinicopathological features, tumor localization, and treatment outcomes. Methods: We retrospectively analyzed 4...

Targeting breast cancer stem cells by restoring RBM38 function: mechanism and protein delivery therapy

Breast cancer stemness drives tumor progression and therapy resistance, yet the underlying mechanisms remain poorly understood. In this study, we observed that RBM38 expression gradually decreases during breast cancer progression in MMTV - PyMT transgenic mice. Using a model with...

Interstitial lung disease in pregnancy

Interstitial lung disease (ILD) comprises a heterogeneous group of chronic pulmonary disorders. ILD is associated with impaired gas exchange and progressive respiratory dysfunction. Due to improved survival and delayed childbearing, healthcare providers increasingly encounter pre...

A Tautomeric Carbon Nitride Structure for Photocatalytic Overall Water Splitting

Constructing type-II heterojunctions is a prevalent strategy for enhancing the photocatalytic performance of polymeric carbon nitride (PCN). However, conventional PCN-based type-II heterojunctions are often limited by incoherent interfacial contacts, high charge-transfer resistan...

A review of pretreatment and analytical techniques for amphetamine type stimulants in complex samples

Amphetamine-type stimulants (ATSs) are among the most widely abused drugs globally, posing serious threats to public health through addiction, physical and psychological harm, and associated social problems such as increased crime rates. Effective clinical management of ATSs over...

Short-Term Changes, Individual Variability, and Associations with Baseline Physical Performance in Young Male Soccer Players During the Pre-Season

Monitoring physical performance during the pre-season may help coaches and practitioners interpret short-term changes in young soccer players, although group-level analyses may mask individual variability. This observational longitudinal study analyzed short-term changes, individ...

Firefighter well-being in the Baltics: a comparative study of physical activity, psychosocial risks, and management strategies in Estonian and Latvian fire services

Firefighting demands exceptional physical and cognitive capacity in hazardous, unpredictable environments. This comparative study examined firefighter well-being in Estonia and Latvia using the job demands-resources (JD-R) model. A mixed-methods approach (2020‒2024) included qu...