Research works

Exohedral 1:2Complexes of Lanthanide Atoms with theC60 Fullerene: What Hapticity Is Preferred, η10, η11, or η12?

Abstract The structure of crystalline lanthanide–C60 fullerides allows for the Ln atom coordination to two rings of adjacent fullerene molecules simultaneously, where the resulting Ln hapticity can be η10, η11, or η12. We analyze the geometries, bonding strength, charge, spin, an...

Rational design, synthesis, and antimicrobial evaluation of novel 1,2,3-triazole hybrids: structure–activity relationships, molecular docking, and DFT studies

A series of novel 2,4-dichlorophenyl-1,2,3-triazole derivatives and their structural hybrids incorporating chalcone, hydrazone, thio/semicarbazide, carbamate, and pyrazole moieties were rationally designed, synthesized, and characterized. The antimicrobial activity of the synthes...

An Unusual Case of Takotsubo Syndrome with Extreme QTc Prolongation: A Case Report

Abstract Introduction Takotsubo syndrome is a transient stress-induced cardiomyopathy characterized by reversible left ventricular dysfunction and dynamic electrocardiographic abnormalities. QTc prolongation is common and may increase the risk of malignant ventricular arrhythmias...

Evaluation of aerosol delivery in ventilated patients via vibrating mesh nebuliser versus other delivery devices using a patient-specific in silico whole-lung model

Abstract Background In patients requiring mechanical ventilation, normal aerosol dynamics are disrupted by the artificial airway, circuit configuration and humidification systems. These factors can result in substantial drug losses within the ventilator circuit and markedly lower...

Civilization in the Age of AI: Civilization as a Social System for Realizing and Advancing Capability Continuity

This conceptual paper reinterprets civilization in the age of AI through Capability Continuity: the capacity to form, preserve, transfer, adapt, and further develop capabilities across changes in time, generations, and environments. It argues that writing, education, professional...

Short Elucidating Note 126: Stating the structural falsification theorem for specific paradigms of the form K = L, its main conceptual applications and its extension of Popperian logic and of Kuhnian logic all in compressed form using set theory and sustainability gap theory?

The specific paradigm’s structural falsification theory suggest that paradigms of the conjunctural form K = L or inherently conjunctural paradigms that claim to have such a form invalidate themselves when applying unilateral pressures (e.g. Maximization, optimization, growth, de-...

Robotic, laparoscopic, and open nephrectomy and 30-day pulmonary morbidity: a procedure-stratified cohort study with intraoperative ventilation data

Previous studies of heterogeneous abdominal procedures have reported higher pulmonary-complication rates after robot-assisted surgery, but whether this applies to nephrectomy is uncertain. We evaluated surgical approach and 30-day postoperative pulmonary complications (PPCs) afte...

The Promethean-Serpent of Eden is the True Founder of Capitalist Libertarianism: A Refutation of the Paleolibertarian Idea that God is a Libertarian

The myth of the creation of Adam and Eve and their expulsion from the Garden of Eden is an allegory demonstrating that God—far from being a libertarian authority who does not intervene in His creation—is quite the opposite: a statist authority who created the first human couple t...

ElectrochemicalSynthesis of β-ArylaminoKetones from Tertiary Anilines and Silyl Enol Ethers

Abstract A novel strategy for the green and efficient electrochemical synthesis of β-arylamino ketones has been developed through the reaction of readily available tertiary anilines with silyl enol ethers. This metal- and oxidant-free method operates under mild conditions and del...

Previously undiagnosed pulmonary arteriovenous malformation in hereditary hemorrhagic telangiectasia presenting as a brain abscess: a case report

Abstract Introduction Pulmonary arteriovenous malformations (PAVMs) are abnormal vascular connections that predispose to paradoxical embolism and brain abscess formation. They often remain undetected until severe complications occur, posing significant diagnostic challenges. Case...

Hypoxia increases the activity of oncolytic adenoviruses through HIF-2α-stimulated E1A expression

Hypoxia, a hallmark of solid tumors, poses a significant challenge in cancer therapy due to its association with poor prognosis and resistance to conventional treatments. Oncolytic viruses represent a promising treatment strategy, as they selectively replicate within cancer cells...

The American Founding Documents and Democratic Social Change: A Constructivist Grounded Theory

Existing social disparities in the United States are inconsistent with the promise of democracy; therefore, there was a need for critical conceptualization of the firstprinciples that undergird American democracy and the genesis of democratic social change in America. This constr...

Strategic Audit Redesign in the GenAI and Agentic AI Era: Safeguarding Talent and Elevating Professional Judgment

The rapid integration of generative artificial intelligence (GenAI) and emerging agentic AI systems is reshaping the audit profession, with significant implications for workforce development, audit methodologies, and human–AI collaboration. Although public narratives often depict...

Fatal infantile encephalopathy due to NAXE variant: Navigating the Metabolic-Mitochondrial overlap in NAXE gene

Abstract Background Progressive Encephalopathy with Brain Edema and/or Leukoencephalopathy-1 (PEBEL-1) is a rare, rapidly progressive, and often fatal infantile neurometabolic disorder caused by pathogenic variants in the NAXE gene. Loss of NAXE impairs the NAD(P)HX repair pathwa...

Chilled and freeze-dried preservation of saltwater crocodile (Crocodylus porosus) spermatozoa

CONTEXT: Artificial insemination in farmed crocodiles is limited by poor sperm survival after cryopreservation, requiring alternative preservation strategies. AIMS: This study evaluated the effects of three extenders on saltwater crocodile (Crocodylus porosus) semen during chille...

Workplace civility climate and its relationship with organizational citizenship behavior and intention to stay among nurses

Abstract Background A workplace civility climate is a critical factor in shaping healthy nursing work environments. It influences nurses’ organizational citizenship behavior (OCB) and intention to stay, yet evidence from many healthcare systems, including Egypt, remains limited....

Quantifying the social net: a nomogram to predict baseline quality of life at clinical entry for head and neck cancer

Abstract Background Quality of life (QoL) and psychological distress are critical yet under-evaluated dimensions of head and neck squamous cell carcinoma (HNSCC) management. While clinical staging is a primary determinant of survival, the influence of the socio-economic “safety n...

The Nested Cosmic Organization Hypothesis (NCOH): A Refined Research Framework for Multiscale Causal Emergence, Astrophysical Thermodynamics, Information Integration, and Cosmopsychism

The Nested Cosmic Organization Hypothesis (NCOH) proposes that physical reality exhibits a hierarchy of organizational scales — from quantum and molecular systems through cells, organisms, ecosystems, planetary systems, galaxies, and the cosmic web — at which qualitatively distin...

A ComplexSpin-Transition Thermal Hysteresis Unlockedby Two Competing Symmetry-Breakings

Abstract The spin-crossover material [Fe(NH2trz)3](NO3)2 belongs to the class of 1D triazole-based polymeric SCO complexes. It exhibits a thermal phase transition, with a 28 K wide thermal hysteresis, characterized by phase transition temperatures T↑ = 346 K upon warming and T↓ =...

Control of PhotoinducedLigand Detachment from QuantumDot Surfaces Using Nanocrystal Architecture

Abstract We investigated the influence that nanocrystal architecture has on the extent to which colloidal quantum dots undergo photoinduced ligand detachment. We took advantage of the ability of electrons to delocalize throughout both the core and shell of CdSe/CdS core/shell nan...