Research works

Transcriptomic and Extracellular Proteomic Analyses Implicate Two-Component Signaling in Medium-Dependent Virulence in Vibrio mediterranei

Vibrio mediterranei is an emerging pathogen causing vibriosis outbreaks in marine bivalves, yet the molecular mechanisms by which environmental conditions modulate its virulence remain poorly understood. Here, we combined in vivo infection assays with integrated transcriptomic an...

The Golden Ratio as a Fixed Point in Algorithmic Randomness and Prefix Complexity — E8 Intelligence Research

FINDING: Algorithmic randomness and Kolmogorov complexity intersect with the golden ratio via stable self-application, linking prefix-free coding to irrational recurrence. | MATH: Prefix complexity \(K(x)\) satisfies \(K(x) \leq -\log_2 m(x) + O(1)\) where \(m(x)\) is a priori pr...

CREST functions as a molecular bridge between neuron-specific enhancers and epigenetic regulators in mature motor neurons

Abstract Motor neuron development requires precise transcriptional regulation mediated in part by BAF (BRG1/BRM-associated factor) chromatin remodeling complexes. The neuron-specific BAF subunit CREST is critical for neuronal function and is mutated in some cases of amyotrophic l...

A Fuzzy Gain-Scheduled Time Base Generator for Fixed-Time Leader-Following Tracking Consensus of Feedforward Nonlinear Multi-Agent Systems

This paper proposes a fuzzy gain-scheduled time base generator (FGS-TBG) framework for prescribed fixed-time leader-following consensus of Lipschitz feedforward nonlinear multi-agent systems (FNMASs) with a dynamic leader under distributed output feedback. Existing TBG-based fixe...

RLMT: Do Shortcuts Through the R-Direction Exist? Constraints from GW170817 and the Layered Expansion of Vol. XLI-L

If four-dimensional spacetime is a projection from a higher-dimensional manifold, signals that travel through the extra direction could arrive before light confined to four dimensions. R-layer Mode Theory (RLMT) contains such a direction, the layer coordinate R with five-dimensio...

Translating the myth: Şahmaran and the production of value across Turkish media

Abstract This study examines the positioning and legitimation of the cultural figure of Şahmaran (Shahmaran) as a process of value transformation across three audiovisual and institutional regimes: artistic production, heritage-oriented discourse, and platform-mediated popular me...

Infinite Series About Reciprocal Products of Fibonacci and Lucas Numbers

Infinite series about reciprocal products of Fibonacci and Lucas numbers are systematically examined. This is done by incorporating the telescoping method, Cassini-like identities and partial fractions, as well as the induction principle. Numerous closed formulae are presented wi...

DEVELOPMENT AND VALIDATION OF AN RP-HPLC METHOD FOR THE DETERMINATION OF APIXABAN IN BULK AND TABLET DOSAGE FORM

Reliable analytical techniques are crucial for the quantitative determination of Apixaban, a Anti-Coagulant drug used to Deep vein thrombosis, Pulmonary embolism in pharmaceutical formulations. The goal of the current work was to create and validate a straightforward, accurate, a...

Cogenital double patella: two cases of a rare anatomical variant

Abstract Congenital double patella is an exceptionally rare anatomical anomaly, with fewer than 50 cases reported in the literature. Owing to its rarity and variable anatomical presentation, diagnosis may be challenging and requires careful imaging assessment. We report two cases...

Physically Constrained Temporal Fusion Transformer with LLM-Assisted Hyperparameter Optimization for Multi-Scenario Energy Time Series Forecasting

Accurate forecasting of battery state of health (SOH), wind power, and photovoltaic (PV) power is challenged by non-stationarity, multiscale dependencies, and physically implausible outputs. This study proposes a physically constrained Temporal Fusion Transformer (PC-TFT) that co...

THE EFFECTS OF LABORATORY PRACTICES ON HEAVY METAL CONTAMINATION OF WATER SOURCES IN TERTIARY INSTITUTIONS

Science, engineering, and health-related laboratories in tertiary institutions generate liquid waste that may contain toxic heavy metals, including lead, cadmium, chromium, manganese, and iron. Poor segregation, treatment, handling, and disposal of laboratory waste may contaminat...

Improving Dystonia Management of Children Admitted for Elective Surgical Procedures: A Quality Improvement Project

Background Children and young people (CYP) with neurodisability may suffer dystonia exacerbations in the peri- and post-operative period. Objectives This study aimed to identify dystonia-related outcomes for CYP admitted to Evelina Children's Hospital. Methods Elective admissions...

Construction characteristics of Huizhou traditional wooden ancestral hall architecture in the context of beautiful rural areas: Xidi Hu Clan Ancestral Hall as a case study

The traditional ancestral halls of Huizhou represent a significant architectural heritage in southern Anhui, reflecting the sophisticated construction techniques and structural knowledge of the Ming and Qing dynasties. In the context of ongoing rural revitalization, systematic in...

Beyond Histocompatibility: Donor Tissue Immune States and Their Role in Heart Transplantation

Heart transplantation transfers not only donor alloantigens and functional myocardium but also a pre-existing tissue environment shaped by resident immune, vascular, stromal, and parenchymal populations. This review examines the hypothesis that the biological state of donor tissu...

Rodan & Fields launches new STEM partnership with Girls Inc.

Rodan & Fields, a provider of skincare products, has announced a $350,000 partnership with Girls Inc. to invest directly in the new generation of female founders and science, technology, engineering and mathematics innovators. The initiative includes a $100,000 investment in the...

Parameter Estimation of a Single-Phase Diode-Bridge Rectifier Under Steady-State, Load Variation, and Startup Transient Using Terminal Measurements

This paper presents a numerical framework for parameter estimation of a single-phase diode-bridge rectifier with capacitive filtering. The proposed approach integrates a state-space model of the rectifier, numerically solved using the second-order Backward Differentiation Formula...

Limb Salvage Outcomes Following Endovascular Revascularization for Peripheral Artery Disease in a Southern Indian Population: A Single-Center Retrospective Study

BackgroundPeripheral artery disease (PAD), particularly chronic limb-threatening ischemia (CLTI), is associated with a high risk of limb loss and significant morbidity.Endovascular therapy (ET) has emerged as a minimally invasive alternative to surgical revascularization, especia...

Evaluating the performance of long short-term memory to other time series models for univariate and multivariate data

Abstract Time series data analysis is one of the difficult tasks in real-world data problems because the data entities are determined not only by physical causes, but also by the chronological sequence in which they occurred. In this work, we have examined how Long Short-Term Mem...

The Institutional Topology of "Simulated Prohibition": Rent-Seeking, Logistics Enclosures, and Regulatory Theater from the Volstead Act to Frontier AI Governance

【Abstract】This institutional economics and technology governance monograph deconstructs the structural mythology of total legal bans through a comparative analysis of the 1920s United States National Prohibition Act (the Volstead Act) and contemporary regulatory frameworks targ...

Toward Integrated Upcycling of Lithium‐Ion Battery: Advances and Outlooks

The imminent retirement of large batches of lithium‐ion batteries poses a critical challenge to sustainable resource management. While present recycling technologies have demonstrated certain advantages over conventional metallurgical methods, the comprehensive assessment of thei...