Research works

MRI-based radiomic models of subchondral bone for predicting the occurrence of knee osteoarthritis

To extract the MRI-based radiomic features of subchondral bone, and establish multi-regional radiomic models and delta-radiomic models for predicting the 2-year risk of knee osteoarthritis (KOA). The data used in this study were obtained from the osteoarthritis initiative (OAI)....

A hybrid time-weighted dynamic time warping and TKNN classifier for paddy rice mapping using time-series Sentinel-1 SAR data

Accurate rice extraction is essential for agricultural monitoring. However, traditional methods using Euclidean Distance (ED) or Dynamic Time Warping (DTW) are limited by noise sensitivity and ignoring temporal order. This paper proposes a new method combining Time-Weighted Dynam...

Redefining Success and Characterizing Midterm Growth Modulation: Analysis of Radiographic Outcomes in 2 Years Following Vertebral Body Tethering.

Background: Vertebral body tethering (VBT) offers fusionless correction for idiopathic scoliosis, yet midterm growth modulation remains poorly characterized. This study established a clinically relevant success criterion and characterized growth modulation kinetics with associate...

Simpler Graph Conditions for Embedding Tetrahedral Meshes

Three-dimensional Tutte-style embedding methods turn graph conditions into guarantees for tetrahedral meshes. Alexa's theorem excludes both K_6 and K_(3,3,1) as graph minors and asks whether the second exclusion is necessary. We prove that it is redundant for a precisely defined...

Dental Erosion and Therapeutic Options

Tooth wear is a common, multifactorial non-carious dental hard tissue disease, and it may lead to a range of problems such as hypersensitivity, occlusal dysfunction, and aesthetic defects, significantly impacting patients’ oral health and quality of life. This article aims to sys...

Predicting and Controlling Hallucination Onset in Large Language Models: A Belief-State Framework for Prospective Risk, Optimal Intervention, and Recoverability

Hallucination mitigation in large language models (LLMs) is commonly approached through post-hoc factuality checks, uncertainty scores, token- or span-level detectors, or abstention rules. These methods are valuable but do not fully specify the sequential decision problem that ar...

Traditional Chinese Medicine for Chronic Obstructive Pulmonary Disease: Treatment Strategies, Clinical Evidence, and Mechanistic Insights

Chronic obstructive pulmonary disease (COPD) is a prevalent, preventable, and treatable chronic airway disease associated with high morbidity, mortality, and global burden. For this review, we searched PubMed, Web of Science, and major Chinese academic databases for clinical and...

Failures to maintain CpG-methylation of CoRSIVs in bovine sperm are associated with low sire conception

CoRSIVs are genomic regions with CpG-methylation patterns that differ between individuals, yet are consistent between tissues, within the same individual; therefore, their methylation can be profiled in bodily fluids that are easily obtained, like blood and semen. Bearing in mind...

The Effect of Media, Conditioned by Serratia proteamaculans and Enriched with ShlA Toxin, on the Permeability of Lipid Bilayers, Mimicking the Membranes of Epithelial Cells HeLa and Caco-2

Abstract— In this work we investigated the pore-forming activity of ShlA toxin from Serratia proteamaculans in lipid bilayers modelling the membranes of epithelial cells HeLa and Caco-2 and assessed the role of CaCl2 in its modification. It was found that the addition of conditio...

Nonlinear Mixed-Effects Modeling of Height to Live Crown Base in Natural and Plantation Jack Pine Stands

Height to live crown base (HCB) is a key indicator of crown architecture, influencing growth allocation, timber quality, and stand dynamics in boreal forests. Accurate prediction of HCB is essential for growth and yield modeling and silvicultural planning. Using measurements from...

Impedance pneumography to explore bronchial obstruction in young infants born moderate-late preterm: a cohort study

Background Wheezing, a symptom reflecting bronchial obstruction, is frequently reported in preterm-born infants. No objective and reliable tool is available to assert this diagnosis with minimal patient cooperation. Nocturnal tidal breathing measurements by impedance pneumography...

Teacher Attitudes Towards and Experience with Trauma-Informed Care: Associations with Secondary Traumatic Stress

Abstract Teachers provide crucial support to the psychosocial, emotional, and academic development of students affected by trauma; however, such support can come at a cost to teachers’ health and attrition. The present study aimed to identify secondary traumatic stress (STS) leve...

Determination of Efficacy of Intervention based on the Cognitive-Behavioral Therapy Model of Panic Attack Treatment in Comorbid Heart Diseases: A Pilot Randomized Controlled Trial

Background: Panic disorder (PD) and cardiovascular disease (CVD) exhibit similar symptoms, such as palpitations, dyspnea, and chest pain, complicating clinical differentiation, especially when they coexist. This overlap has led to challenges in the context of psychocardiology, in...

Systems Bioengineering of Septic Shock Metabolism: Citrulline, β-Hydroxybutyrate and Plasma Biomarker-Based Phenotyping

Background: Although advances in critical care have improved short-term outcomes, sepsis survivors continue to face substantial chronic morbidity and impaired long-term survival. Conventional threshold-based tools such as the Sequential Organ Failure Assessment (SOFA) and Modifie...

Transforming biomedical uncertainty: the sociohistorical origins of myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS)

Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are serious and disabling long-term conditions characterised by uncertainty surrounding their aetiology, diagnosis and treatment. People with ME/CFS struggle to be understood, taken seriously and supported with the...

Teacher motivation and teacher-perceived student performance: The mediating role of teacher self-efficacy and the moderating roles of workload and school climate

Grounded in job demands–resources theory, this study examined whether teacher motivation was associated with teacher-perceived student performance directly and statistically indirectly through teacher self-efficacy, and whether workload and school climate conditioned the first-st...

Induced proximity-based therapeutics for advanced prostate cancer

Abstract Metastatic castration-resistant prostate cancers (mCRPC) remain dependent on androgen receptor (AR) signaling despite resistance to androgen-deprivation and AR-targeted therapies. Induced proximity-based therapeutics employ event-driven pharmacology to target AR, potenti...

Continuing Trend of Increased Operative Treatment of Clavicle Fractures in Pediatric Patients in the United States Despite a Lack of Supporting Evidence in the Literature

Introduction: Pediatric clavicle fractures are among the most common fractures in this age group. Current research supports the efficacy of nonoperative treatment for these injuries in pediatric patients. Our study seeks to examine the current trends in the management of these fr...

Sector Paper XXII — Extreme‑Field Collapse‑Energy Geometry and δI‑Gradient Horizon Amplification in Magnetar Regimes

Sector XXII presents the extreme‑field collapse‑energy geometry of the Unified Information Substrate, demonstrating how δI‑gradient amplification in magnetar‑scale and horizon‑proximal regimes produces forced geometric contraction, collapse‑energy intensification, and horizon‑zon...

Simultaneously Improving the Selectivity and Stability of HZSM-5 Zeolite by NaOH Treatment in Aqueous Ethanol-to-Propylene Reactions

Mesoporous nanoscale HZSM-5 zeolites were prepared by alkali treatment and characterized by XRD, SEM, NMR, ICP-OES, N2 adsorption/desorption, NH3-TPD, Py-IR, and TG techniques. The effects of NaOH concentration on pore structure, acidity, and catalytic performance of nanoscale HZ...