Research works

Open-Source Model Watermarking: Technical Approaches and Robustness Against Removal

Research article: Open-Source Model Watermarking: Technical Approaches and Robustness Against Removal

Application of dual-view oblique plane microscopy to small-molecule compound screening across 3D glioblastoma stem cell spheroids with single-cell resolution

Recent advances and increasing adoption of 3-dimensional (3D) model systems, such as tumour spheroids and organoids, attempt to more faithfully recapitulate the pathophysiology and heterogeneity observed in patients' tumours, with the goal of reducing high attrition rates observe...

Liquidity Valuation Adjustment for Standby Swaps

This paper outlines an approach to calculating a liquidity valuation adjustment (LVA) for standby swaps, which are credit instruments used in securitisation markets to transfer rating agency obligations between swap providers. We define the LVA of a standby swap in the presence o...

BASE 44 ORDER: Build e8_breakthrough_cache table with composite index and 24h TTL — E8 Intelligence Research

Andrew's order (Base 44 console): [SELF-BUILD from enhancement #1101] Create `e8_breakthrough_cache` table with columns e8_hash BIGINT, query_hash BIGINT, response TEXT, created_at TIMESTAMP. Add composite B-tree index on (e8_hash, query_hash). Modify agent to compute E8 hash bef...

A Cell-Based Ocean-Current-Aware Travel-Time Cost Formulation for Offline 3D Path Planning of Underwater Vehicles

Underwater vehicles must operate efficiently within the limits of their onboard resources, and travel time is a primary operational objective for extending submerged endurance and range. Ocean currents significantly affect vehicle motion and travel time, either aiding or impeding...

Plural Social Justice in the Graduation Profiles of Social Work Programs at Chilean State Universities

This article analyzes the explicit and implicit presence of social justice in the graduation profiles of Social Work programs at Chilean state universities, as well as the way in which its distributive, recognition, and participatory dimensions are articulated within the declarat...

Independent Domination under Iterated Line Graphs: The Regular Case

Version 1.0.0. For a graph parameter P and a prolific graph G, Caro, Lauri and Zarb defined the index ind(P,G) as the first iterated line graph on which P exceeds its value on G. This preprint determines the independent-domination index on the class of connected regular graphs of...

MODEL ADOPTION #1015: REJECT — LEDGER BENCH: Apply filter: Min confirmations >= 5 — improves win rate from 31.6% to 33.2% — E8 Intelligence Research

DECISION: REJECT ELEMENT: The filter "min confirmations >= 5" is not a concrete, testable edge compatible with E8 geometry timing. It is a statistical heuristic derived from a backtest that does not isolate the *cause* of the win-rate improvement. The +1.6pp gain may be a spuriou...

The SF3b complex in cancer: structural basis, molecular mechanisms, and therapeutic opportunities

Aberrant alternative splicing is increasingly recognized as a fundamental driver of cancer initiation and progression. The splicing factor 3b (SF3b) complex, an essential component of the U2 small nuclear ribonucleoprotein (snRNP), plays a pivotal role in branch point sequence (B...

From Policy to Practice: A Statewide Model to Expand School-Community Mental Health Partnerships

Abstract Schools are a primary access point for youth mental health services, yet most lack the sustained funding, infrastructure, and partnerships needed to build comprehensive and equitable systems of care. State policy offers a mechanism to address these limitations, but there...

QGD / MPDT and General Relativity: The Aberration Problem, Compared

Newton's instantaneous gravity was abandoned because it appeared incompatible with a finite speed limit and with the empirical fact that orbits do not destabilize under aberration. General relativity resolves this through velocity-dependent terms, forced by general covariance, th...

iCorn: A Methodological Framework for Multi-Label Disease Classification in Maize Using Uncurated Field Images

iCorn: Multi-Label Maize Disease Classification Framework Complete implementation of iCorn—a methodological framework for multi-label classification of maize leaf diseases from uncurated field images using deep learning, with production-ready mobile deployment. **Manuscript**: "i...

Manufacturing technology of ancient gold-in-glass beads from the Kazakh Altai and implications for Eurasian exchange

Abstract Gold-in-glass (GG) beads, composite ornaments encapsulating metal foil between glass layers, are widely distributed across the Mediterranean and Inner Asia, yet their presence and transmission across Inner Asia remain insufficiently understood. In particular, the mechani...

Metallurgical Waste Landfills as Potential Anthropogenic Deposits

Metallurgical slags produced in the zinc–lead, copper, iron and steel metallurgical industries are characterized by a variety of technical parameters and varying chemical and mineral compositions, which depend on the type of raw material and the technological process selected and...

Hyperspectral Camera Imaging Tandem With HPLC‐UV‐ELSD Determination and Cell Bioassay for Geographical Discrimination and Quality Consistency Evaluation of Anoectochilus roxburghii

ABSTRACT Introduction Anoectochilus roxburghii (AR) is a prized medicinal herb valued for its hepatoprotective effects. Its quality varies depending on geographical origin. The primary bioactive constituents include rutin, quercetin‐7‐ O ‐glucoside, kaempferol‐3‐ O ‐rutinoside, n...

New edge proposed: bear_flag_volume_thrust_fade — E8 Intelligence Research

{ "name": "bear_flag_volume_thrust_fade", "source": "Thomas Bulkowski / Encyclopedia of Chart Patterns", "type": "entry_engine", "rule": "Enter short when price breaks below a 5-bar descending flag consolidation (highest high and lowest low both descending, slope<30deg) after a p...

Spontaneous clearance and real-world management after first asymptomatic MRSA isolation in pediatric cystic fibrosis

Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly isolated in people with cystic fibrosis (CF) and has been associated with poorer clinical outcomes in CF populations. Although early treatment after first detection is commonly practiced, management of asymptomati...

Halogen‐Acupuncture Stabilization of Pure‐Iodide Wide‐Bandgap Perovskites for Efficient and Stable Solar Cells under Simulated Low‐Earth‐Orbit Cycling

ABSTRACT Pure‐iodide wide‐bandgap (WBG) perovskites are promising top‐cell absorbers for tandem photovoltaics, benefiting from their intrinsic immunity to the halide phase segregation that plagues mixed‐halide counterparts. However, their practical deployment, particularly in spa...

Uneven development of intangible cultural heritage: A spatial analysis of traditional drama in Southwestern China

Intangible cultural heritage (ICH) exhibits pronounced spatial unevenness, yet the spatial patterns and driving mechanisms of traditional drama as a form of living performing heritage remain insufficiently understood. Taking Southwest China as a case, this study analyzes 257 trad...

Nationwide pediatric injury surveillance across two successive system disruptions in South Korea, 2016–2024

Abstract Background Long-term trends in emergency department (ED)-based pediatric injury surveillance during and after the COVID-19 pandemic remain poorly characterized, particularly in settings that experienced additional system-level disruption. In February 2024, South Korea ex...