Research works

Proteomic analysis of human chronic traumatic encephalopathy brain implicates proteasome and ribosome dysfunction in disease severity

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease that occurs in individuals with repeated head impacts (RHI) exposure, including contact sport athletes, military personnel, and domestic abuse victims. Despite growing recognition of CTE, the molecular mechanis...

Acceptability and Feasibility of a Primary Care Hypoglycemia Prevention Program: A Pilot Study

OBJECTIVE Hypoglycemia, a major cause of morbidity for people with diabetes, is underrecognized in primary care, leading to underuse of risk mitigation strategies. This study reports the development and acceptability/feasibility testing of the Hypoglycemia Prevention Program (HPP...

Dark Matter as Non-Equilibrium Virial Geometry

The dark-matter problem is usually interpreted as evidence for unseen mass. This paper develops a different closure: the missing term may be the finite relaxation of spacetime geometry itself. Starting from the full time-dependent Virial Theorem, the normally discarded non-equili...

Enhancing cowpea quality and soil biochemistry through residual nickel and nitrogen in Vertisol

Nickel (Ni) plays a vital role in plant nitrogen (N) metabolism, yet its use is limited and its residual effects on subsequent rotational crops remain underexplored. The present study evaluated the effect of varying N levels and residual Ni, previously applied to soybean, on the...

Continuous automatic batch identification and characteristic analysis of vortex-induced vibrations of stay cables based on long-term monitoring

Vortex-induced vibration (VIV) is a typical abnormal vibration of stay cables, and long-term monitoring of VIV with in-depth information extraction is critical for bridge safety and maintenance. This study establishes an automatic batch framework for continuous VIV identification...

Demographic transition and the rise of wealth inequality

Abstract We analyse the contribution of rising longevity to the increase in wealth inequality in the U.S. over the past seventy years. To do so, we construct an overlapping generations (OLG) model with multiple sources of inequality, carefully calibrated to the data. Our key find...

Public Awareness of Genetic Diseases, Preventive Screening, and Genetic Healthcare Services in the Qassim Region, Saudi Arabia: A Cross-Sectional Study

Background: Genetic diseases pose a significant public health issue in Saudi Arabia, driven by relatively high prevalence and factors such as consanguineous marriage. Increasing public awareness and understanding are crucial to improving prevention, early detection, and the use o...

The Impact of Educational Interventions on Clinical Documentation Using Pretest–Posttest CRABEL Scores: A Single Group Quasi-Experimental Study among Dental Interns

Abstract Clinical documentation is essential for patient safety, legal protection, and continuity of care. Nevertheless, record-keeping skills are usually overlooked by most undergraduate dental programs. This study investigated the outcomes of a structured educational interventi...

A framework for transformational projects: empirically testing its concept, mechanisms and essential conditions

Purpose This study aims to develop and empirically evaluate a conceptual framework that investigates the impact of organizational transformation on transformational projects, with mediating effects of transformational approach, focus and barriers. Design/methodology/approach Draw...

Prognostic Nutritional Index as a Marker Associated With Disease Severity in Diabetic Kidney Disease: A Real-World North African Experience

Background: Diabetic kidney disease (DKD) is characterized by chronic inflammation and progressive protein-energy wasting. The Prognostic Nutritional Index (PNI) represents a promising marker for assessing immunonutritional deterioration. Our study aims to evaluate the PNI in pat...

A Special Theory of Employment, Interest, and Money

We study a supply-side macro-financial dynamical system in which output velocity V=Y is an independent state variable governed by ˙V = (A/∆)V, where A(·) is effective productive capacity and ∆ = λ(Y−Y₀)−A(·) is an endogenous threshold gap. Output thereby carries momentum, and the...

Front‐Loaded Stabilizations: Lessons From Milei's Chainsaw Reform Program

ABSTRACT The literature on delayed stabilization has built its analytical framework on the premise that stabilization entails costs. We argue that this premise is incorrect: Stabilization and economic reform deliver benefits rather than costs. If so, reforms should be front‐loade...

Lipid Mediators Derived from Docosahexaenoic Acid Alleviate Periodontal Inflammation and Alveolar Bone Loss in Periodontitis Associated with Suppression of the NF-κB and STAT3 Signaling Pathways

Background: Lipid mediators (LM), comprising 17S-hydroxy-docosahexaenoic acid, resolvin D5, and protectin DX in a ratio of 3:47:50, were naturally generated from docosahexaenoic acid by soybean lipoxygenase and exhibit potent anti-inflammatory activities. However, their therapeut...

Hydrological Drought Modeling Under the Impact of Climate Change in the Luanhe River Basin: A Prediction Study

Against the backdrop of climate change and compounded by human activities, increasing water scarcity has triggered a series of drought disasters, which have already severely impacted both ecological environments and socioeconomic production. The SWAT model, recognized for its str...

Halogen Substitution as a “Chirality Editor” for Amplifying Spin‐Selective Transport in Lead‐Free Metal‐Halide Hybrids

ABSTRACT Lead‐free metal‐halide hybrids hold promise as flexible semiconductors for X‐ray detection, but their application is constrained by inefficient carrier transport. Here, we introduce halogen substitution on chiral molecular cations as a “chirality editor” to modulate the...

Helios-Artemis: Design and Simulation-Based Validation of a Dual- Microcontroller Predictive Solar MPPT Controller with On-Device LSTM Retraining for Sylhet Monsoon SHS Deployment in Bangladesh

Revised version of manuscript 25195, under review at the InternationalJournal of Power Electronics and Drive Systems (IJPEDS). **Abstract** This paper addresses the monsoon yield gap of the IDCOL Solar Home System(SHS) programme: conventional reactive Perturb-and-Observe (P&O) MP...

Association between neutrophil-to-HDL cholesterol ratio and diabetic nephropathy in adults with diabetes mellitus

Renal complications in diabetes impose substantial morbidity globally, yet early risk stratification remains challenging. The neutrophil-to-HDL cholesterol ratio (NHR) represents an integrated biomarker reflecting both immune activation and dyslipidemia, with neutrophilia promoti...

Cascaded Multistage Impinging-Jet Solid Fuel Configuration: Experiments and Simulations

This work presents a combined experimental and computational investigation of the Cascaded Multi-Stage Impinging Jet (CAMUI) solid-fuel configuration for hybrid propulsion. CAMUI departs from conventional solid-fuel architectures by arranging orthogonal fuel blocks that force seq...

Transformation-Stable Structures and Emergent Compression

This work proposes a conceptual framework in which observable form, representation, and meaning emerge through transformations across different representational scales. An underlying system may contain a high-dimensional relational structure whose complete state is not directly a...

Agroecological Zoning and Credit Demand Heterogeneity: Implications for CGSL Product Design in South Sudan

Community Group Saving and Lending (CGSL) mechanisms are increasingly important in rural South Sudan because formal financial institutions remain thinly distributed outside urban and peri-urban markets. Yet many CGSL products still treat rural borrowers as if they face the same p...