Research works

Surface-guided radiotherapy reduces residual setup errors in abdominal and pelvic radiotherapy

Abstract Introduction Achieving high setup accuracy is critical in modern radiotherapy, particularly with advanced techniques such as IMRT and VMAT. Surface-Guided Radiotherapy (SGRT) has been introduced to assist patient positioning and enhance setup reproducibility. This study...

Dosimetric comparison and delivery accuracy between DCAT and VMAT for stereotactic body radiotherapy using the deep inspiration breath-hold technique in liver cancer

Abstract Purpose: To compare plan quality and delivery accuracy between Volumetric Modulated Arc Therapy (VMAT) and 3-dimensional Dynamic Conformal Arc Therapy (DCAT) for liver stereotactic body radiotherapy (SBRT) using deep inspiration breath-hold (DIBH). Methods: Fifteen SBRT...

Optical diagnostic design for measuring the radiation front with a mid-leg pumped divertor on DIII-D

The design of an optical diagnostic system to localize the radiation front in a mid-leg pumped divertor configuration on DIII-D is presented. Divertor detachment is a key mechanism for handling power exhaust in tokamaks, and mid-leg pumping offers a promising approach to radiativ...

Sensory stimulation triggers different spike responses in serotonin and dopamine neurons in the dorsal midbrain tegmentum

Abstract The dorsal midbrain tegmentum, including the dorsal raphe nucleus (DRN) and the ventrolateral periaqueductal gray (vlPAG), contains diverse neuronal populations. Within this region, serotonin (5-HT) and dopamine (DA) neurons are the principal monoaminergic cell types and...

Dynamic geometric constraints govern covalent feasibility in KRAS G12C ligands

<title>Abstract</title> Covalent inhibition has emerged as an effective strategy for targeting oncogenic proteins, yet successful covalent engagement depends not only on binding affinity but also on the dynamic preservation of productive electrophile–thiol geometry [1,2]. Motivat...

Functional and structural characterization of dendritic spine pathology in a mouse model of tauopathy

SUMMARY Abnormal deposition of the microtubule-associated protein tau has long been associated with neurodegenerative diseases. While spine loss and neuronal death are hallmarks of tauopathy, how pathological tau affects synaptic activity in vivo and whether functional properties...

Seasonal influenza vaccine effectiveness in Thailand, 2022–2025: a multi-season test-negative design study

<title>Abstract</title> Background Seasonal influenza vaccination is a key public health strategy for reducing influenza-related morbidity and mortality. In Thailand, influenza vaccine effectiveness (VE) is routinely evaluated using surveillance data; however, VE may vary by seas...

Deep-Ultraviolet Surface Plasmon Polaritons and Hot Carrier Properties in Orthorhombic, Tetragonal and Trigonal Mo₂B₂ Monolayers

This dataset is associated with the manuscript entitled “Deep-Ultraviolet Surface Plasmon Polaritons and Hot Carrier Properties in Orthorhombic, Tetragonal and Trigonal Mo₂B₂ Monolayers”, submitted to Optics Express. It contains the JDFTx input files and key output files used in...

Conservation and divergence within the Arabidopsis TPL/TPR corepressor family

Abstract The TOPLESS (TPL) and TOPLESS-RELATED (TPR1–TPR4) corepressors, collectively the Arabidopsis TPX family, are recruited by client proteins to regulate nearly every major plant regulatory program. Here, we dissect the conservation and divergence between paralogs using a co...

CLASPP: A unified model for predicting post-translational modifications

Abstract Post-Translational Modifications (PTMs) are a fundamental mechanism for regulating cellular pathways and increasing the functional diversity of the proteome. Accurately predicting the PTM types that are likely to occur at a given site in the primary sequence is a key cha...

Polymer Quantum Mechanics on Compact Configuration Spaces

“Polymer quantum mechanics” is the name given to a quantization scheme inspired by loop quantum gravity in which the configuration space of the theory is chosen to have a discrete topology. Polymer quantization yields a representation of the canonical commutation relations that i...

European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) guidelines for antimicrobial and non-steroidal anti-inflammatory drug use in bovine respiratory disease

<ns5:p> Background Bovine respiratory disease (BRD) is a major cause of morbidity, mortality, impaired welfare, production loss, and antimicrobial use in cattle. These European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) guidelines provide evidence-based...

Applying the UNECE PIERS Evaluation Methodology for the SDGs to Support the Implementation of Green PPP Projects and Infrastructure: Lessons from Slovenia

Robust evaluation methods are essential for assessing the sustainability of public–private partnerships (PPPs) and advancing the Sustainable Development Goals (SDGs). This study examines the United Nations Economic Commission for Europe (UNECE) People-first PPP and Infrastructure...

Design and fabrication of a multifunctional Zn-Fe@Ag nanocomposite for effective treatment of infections wounds

<title>Abstract</title> Infectious wounds, a common bacterial infection in clinical practice, often experience significantly delayed healing due to local bacterial colonization, macrophage polarization imbalance, and tissue regeneration inhibition, posing persistent challenges fo...

The Hidden Geometry of Transformer Weights: A Canonical Basis for Interpreting Transformer Language Models

Version 2 of the paper "The Hidden Geometry of Transformer Weights". Rotating a Transformer language model into a coordinate system alignedwith its own weight matrices — the canonical basis — reveals a hiddeninternal structure. Version 1 established the descriptive phenomena.Vers...

AI-driven Wi-Fi radar people counting for intelligent IoT and distributed sensing systems

<title>Abstract</title> Counting humans in indoor environments is a key capability for intelligent Internet of Things (IoT) systems, enabling applications such as smart home energy optimization, occupancy-aware automation, and real-time decision-making. With the proliferation of...

Analysis of Perinatal Care in Zambia in the Context of WHO Recommendations

Background/Objectives: Perinatal care is essential for the health and well-being of women and adolescent girls from conception through the first year postpartum. The World Health Organization (WHO) provides evidence-based recommendations aimed at improving the quality of antenata...

Characterization and Anti-Allergic Activity of Exopolysaccharides from a New Probiotic Lacticaseibacillus casei LZ9183

Lactic acid bacteria exopolysaccharides (LAB EPS) have garnered significant interest owing to their beneficial biological properties and safety. This study aimed to screen LAB EPS with comprehensive biological activities and anti-allergic potential from four high-yield strains, i...

Impairment of placental function and maternal-fetal immunity cross-talk by per- and polyfluoroalkyl substances during early pregnancy

Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants that have been associated with adverse pregnancy outcomes and immune dysfunction. However, the impact of PFAS on trophoblast-mediated immune interactions at the maternal-fetal interface remains unc...

Contagion of Affinity: Predicting CDS Spikes in Global Systemically Important Banks

This paper examines the predictive power of credit default swap (CDS) spread correlations in the context of the 2023 Credit Suisse failure. Using a two-window design, we separate a 50-week pre-crisis period from the final two-week “jump” window and evaluate whether historical mar...