Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
35527 work(s)
- BiologyOpen access
Efficient clearance of apoptotic neurons is crucial for mitigating secondary injury after acute ischemic stroke (AIS). Although monocyte-derived macrophages (MDMs) rapidly infiltrate the ischemic brain and upregulate triggering receptor expressed on myeloid cells 2 (TREM2) expres...
- BiologyOpen access
The intratumoral microbiome as an emerging hub in cancer pathogenesis and precision oncology
Over the past decade, the number of microbial communities identified within tumors has increased by 400%. Notably, the intratumoral microbiome, which includes bacteria, fungi, viruses, and other microorganisms within tumor tissues, was first discovered more than a century ago. Ba...
- Health & MedicineOpen access
Entrustable professional activities (EPAs) operationalize competency-based education by linking assessment to observable clinical tasks and supervision decisions. Although EPAs are widely implemented in postgraduate and advanced nursing education, quantitative evidence describing...
- Climate & EnvironmentOpen access
From data to decisions: how neural network input structures propagate to air quality policies
In air-quality planning, Artificial Neural Networks (ANNs) have emerged as surrogate models capable of capturing complex nonlinear relationships between emissions and pollutant concentrations with reduced computational time required by chemical and transport models. However, the...
- BiologyOpen access
Preliminary research indicates that an imbalance between excitation and inhibition may be an early pathological feature of Alzheimer's disease. However, the relevant brain networks, neurotransmitters and genetic mechanisms are still unclear. This study enrolled 27 patients with A...
- Materials & EnergyOpen access
The renewed interest for straw-based cattle housing systems, driven by concerns over animal health and welfare in conventional cubicle barns, has increased the importance of naturally ventilated sloping-floor and other litter barns. However, these housing systems contribute subst...
- Climate & EnvironmentOpen access
Severe inflammatory damage of soft tissues and progressive bone destruction are hallmark features of rheumatoid arthritis (RA), in which over-activated neutrophils and excessive neutrophil extracellular traps (NETs) play a pivotal role during the early stages of the disease. Conv...
- Health & MedicineOpen access
According to the French 2022 National guideline, antifibrotic therapy should be initiated as soon as a diagnosis of idiopathic pulmonary fibrosis (IPF) is made, taking into account the individual assessment of the expected benefit and risks of treatment. However, in practice, tre...
- Health & MedicineOpen access
Peripheral neuropathy affects a substantial proportion of the global population and remains incompletely explained by established risk factors. Preclinical studies suggest that gut dysbiosis can modulate neuroimmune pathways and neuropathic phenotypes. However, synthesis of human...
- Climate & EnvironmentOpen access
This study investigated the particulate and heavy metal emissions arising from automotive paint applications. A total of 22 sampling locations, represented as AQ1 - AQ22 for this study. Concentrations of particulate matters were determined using Aerocet 831 particle counter while...
- Health & MedicineOpen access
Whether recorded deaths in intensive care units (ICUs) follow a uniform temporal distribution throughout the 24-hour cycle remains uncertain. Previous studies have primarily compared broad day–night periods, potentially overlooking finer temporal patterns. We investigated the tem...
- Health & MedicineOpen access
Metabolic dysfunction–associated steatotic liver disease (MASLD) is increasingly prevalent among women of reproductive age; however, its association with reproductive outcomes after in vitro fertilization (IVF) remains insufficiently characterized in population-level data. We eva...
- Society & EconomicsOpen access
Against the backdrop of population aging, promoting healthy aging is a core strategy for aging governance in China. Driven by unbalanced rural–urban development, the associations between relevant factors and healthy aging among older adults may exhibit distinct rural–urban hetero...
- Health & MedicineOpen access
Adolescence and young adulthood is characterised by complex developmental and psychosocial changes. The diagnosis of a life-limiting condition adds complexity and stress to this already turbulent period of life. Provision of developmentally appropriate palliative care to this gro...
- Engineering & TechnologyOpen access
Microbial technologies for sustainable recovery of critical metals from battery waste
Due to the high need for energy storage around the globe, there’s an urgent need for to recycle spent batteries in greener ways. Microbial-assisted recycling is one of the methods, where specialized microorganisms are used to extract metals and recover valuable materials from spe...
- Health & MedicineOpen access
This study aims to investigate the epidemiological characteristics and distribution patterns of respiratory pathogens in children in Fuzhou between 2019 and 2024, with a particular focus on changes associated with the COVID-19 pandemic. This retrospective study included children...
- Health & MedicineOpen access
This systematic review aimed to evaluate the prevalence and risk factors of Incontinence-Associated Dermatitis (IAD) in elderly patients. A systematic search was conducted across 10 databases, including PubMed, Embase, Web of Science, Cochrane Library, CINAHL, Ovid MEDLINE, Scopu...
- Society & EconomicsOpen access
Perception and coping with aging among middle-aged women: a qualitative study
Middle-aged women face distinct physiological, psychological, and social challenges during the transition from adulthood to later life. However, their perceptions of aging and the strategies they employ to cope with this process remain insufficiently understood. This qualitative...
- Health & MedicineOpen access
Adoptive cellular immunotherapy has transformed the treatment landscape for hematologic malignancies; however, its broader application to solid tumors remains limited by antigen heterogeneity, inadequate persistence, restricted tumor infiltration, and the profoundly immunosuppres...
- Health & MedicineOpen access
Based on the Chronic Illness Trajectory Framework (CITF), this study aims to explore the longitudinal trajectories and dynamic reciprocal relationships between cognitive function and life-space mobility in older patients with ischemic stroke (IS) during a 1-year post-discharge fo...