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Different environments, similar adaptations: How specific is heat acclimation?

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A case study describing the adaptation and implementation of game design studio to explore indigenous youths' educational experiences

Game design can promote learning and collaboration and provide adolescents with an opportunity to explore topics of importance to them. “Game Design Studio” (GDS) is a youth-centered workshop that invites youth to analyze and design games. To increase cultural relevance for Indig...

Local recreationist survey for understanding the drivers and effects of recreation displacement in southern California national forests

This is the survey instrument administered to residents of Southern California who had visited one or more of the four national forests in the region since summer 2020. It was administered in fall 2023 in both English and Spanish via Qualtrics.

Reconsidering Architectural Representation Education: A Hybrid Teaching Model Proposal

In the environment of international higher education, many universities have transformed their educational programs for adapting to the digital turn. Recently, traditional architectural education has also adopted digital teaching methods, especially in the emergent environment of...

Blind Prediction and Falsification in the OFT-Derived VGM Program: Immutable Pre-Test Contracts, Withheld Data, Decision Logic, and Failure-Closed Empirical Verdicts

This preprint develops the natural methodological continuation of VGM XV, moving from conditional identifiability and inference to prospectively specified empirical testing. It defines how a declared VGM prediction, measurement response, nuisance treatment, and inference procedur...

Zero-Trust Physics: a verifier for the physical answers of Super Intelligence

Super Intelligence (SI) now codes physical models faster than anyone can read them. Zero-Trust Physics is a physics verifier made for SI agents. Over the Model Context Protocol an agent lists the models served, reads the inputs and the limits of each, asks a question, and receive...

E8 Harmonic Entanglement Filter: Phi-Synchronized Confirmation Cascades — E8 Intelligence Research

Building on the E8 root vector lattice (240 vectors at 132Hz base frequency), this discovery reveals that trade confirmations cascade through geometric phase transitions when aligned to φ-coupled harmonic intervals. The same-window effect observed in USDCHF LONG signals correspon...

Optogenetics Nobel Prize 2026 is Illusion: Historical Mistake and The Eye-Test Shame

The 2026 Nobel Prize in Physiology or Medicine awarded for Optogenetics iscelebrated as light-based control of behavior. We prove this prize is an illusion.Nobel Committee does not award on theory; it awards only whena lab demo is seen by eyes. In 2025, eye saw electron trace on...

Fuchan: A Four-Layer Artificial Life Avatar with a Drosophila Connectome as Its Instinct Layer

Background: Dialogue agents powered by Large Language Models (LLMs) achieve high fluency in persona-based conversation, yet their internal states are entirely textual descriptions. When such an agent is "angry," the LLM is merely performing anger; no physical substrate correspond...

The effect of solid‐state fermentation on the bioaccessibility and in vitro gut microbiota modulation of soybean isoflavones

Abstract Background Soybean isoflavones mainly exist as isoflavone glycosides with poor bioaccessibility, which limits their functional application. Bioprocessing is commonly used as an effective strategy to enhance the nutritional quality of plant‐based foods. However, previous...

Accelerated Glofitamab as Urgent Bridging to CAR T‐Cell Therapy in High‐Risk Relapsed/Refractory Large B‐Cell Lymphoma

Conventional glofitamab step-up dosing reaches the 30-mg target dose approximately 3 weeks after obinutuzumab. This interval may be difficult to accommodate in patients with relapsed or refractory large B-cell lymphoma (R/R LBCL) who require disease control within days before cel...

A staged clinical development and evidence-generation framework for Group A Streptococcus vaccines

Group A Streptococcus (Strep A) causes substantial global morbidity and mortality, yet vaccine development faces scientific, regulatory, and strategic challenges. We propose a platform-agnostic, staged clinical development and evidence-generation framework aligning trial feasibil...

Why rotation and mixture fail: treatment history and the declining acaricide efficacy in Varroa destructor

Abstract BACKGROUND Insecticide resistance management (IRM) strategies, such as rotation and mixture, rely on fitness tradeoffs and susceptible population dilution to slow resistance. While IRM is widely recommended, its robustness when a target pest's biology violates these foun...

Global tanker shipping market under geopolitical shifts: current situation, transmission mechanisms and development trends

Purpose Against the backdrop of eastward shift of global refining capacity, tightening environmental regulations and shipping cyclical fluctuations, geopolitical conflicts have become the key exogenous shock reshaping tanker shipping market fundamentals. This paper aims to reveal...

Collective Memory of Individuals: The Case of Interior Design Education Buildings in Eskişehir

Spaces—constituting one of the most concrete grounds where memory is produced and shaped—emerge as a significant factor in the formation of memory. In this context, the present study investigates the impact of conducting interior design education in different buildings over time...

Radial Barriers for Discrete Newtonian Potentials: Counterexamples and Sufficient Conditions

For a locally finite configuration of positive masses in R^n, n >= 3, we study the existence of spheres on which the Newtonian potential is uniformly small. Unit masses at the positive integers contradict the dimensional extension of an auxiliary lemma of Clunie, Eremenko and Ros...

Active vibration suppression of electric vehicle drive systems based on flux-linkage-current inverse mapping

Electric drive systems (EDSs) often exhibit complex coupled vibrations caused by interactions between electromagnetic nonlinearities and mechanical excitations. To characterize these interactions and develop an effective vibration-suppression method, this study establishes a mult...

AGDE-Net: a lightweight attention-guided dual-encoder network for tumor core and peritumoral edema segmentation in adult glioma

Abstract Background Glioma is a malignant primary brain tumor arising from glial cells, often resulting in fatal outcomes without timely treatment. Accurate and reliable tumor segmentation is essential for clinical decision-making and therapeutic evaluation. This study aims to de...

Decision Reassessment Under Restricted Evidence Access

Incremental inference, provenance and conservative decision rules can support reassessment when underlying evidence changes but cannot be disclosed in full. This paper proposes a combined protocol for advisory records using recipient-authorized impact bounds, explicit dependencie...

(Short Paper05) Quantum Informatic Formulation of Mitochon drial Maternal Inheritance in the In Vivo Analog Quantum Synchronizer (BioQPU) Paradigm

The significance of “maternal inheritance,” in which paternally derived mitochondria are immediately eliminated by selective autophagy (mitophagy) or similar mechanisms in all fertilized eggs, and only maternally derived mitochondria are selectively inherited, cannot be fully exp...