Research works

(Methyl)thianthrenium Salt Assisted Metal-Free Protocol for the Synthesis of N- Sulfonyl Formamidines

Abstract A new strategy for the rapid and efficient synthesis of N-sulfonyl formamidines has been developed through the activation of N,N-dimethylformamide (DMF), assisted by (Methyl)thianthrenium salt under ambient conditions. The protocol offers a metal and oxidant-free process...

Epidemiology, characterization, and biocontrol of coffee berry disease in the Gedeo zone, southern Ethiopia

Abstract Coffee berry disease is the most damaging fungal disease of coffee in the Gedeo zone, which results in substantial yield losses. The status of the coffee berry disease is unknown, and there is limited information on characterization and in vitro bioassay against Colletot...

Investigating Whether Behavioral Reaction Time Patterns can Predict Structural Brain Phenotypes Using Models

The individual extent to the content of behavioral data, and neuroimaging is rapidly growing everyday. However, the notice of information about neuroimaging and its variations from behavioral data remains unclear. This study investigated whether it is possible, and if so, to what...

Trans-SAC: gamification design for sustained user engagement in residential demand response

Abstract Residential Demand Response (DR) is a critical mechanism for maintaining the supply-demand balance in modern smart grids. While gamification has recently emerged as a promising strategy to incentivize residential participation, existing programs suffer from severe long-t...

Structural thermodynamics of adsorption on UiO-66 Metal–organic frameworks: A unified thermodynamic framework for surface energetics, Lewis acid–base interactions, and polar surface energy

A comprehensive thermodynamic framework is developed for the structural and energetic characterization of the UiO-66 family of metal–organic frameworks using inverse gas chromatography at infinite dilution. Pristine UiO-66 together with amino-, formic acid-, and acetic acid-funct...

Surface Reconstruction-Driven Insulating Behavior in Metallic Charge-Density-Wave 1T-TaSe2

Abstract Bulk 1T-TaSe2 is metallic, yet its surface consistently exhibits an insulating gap─a dichotomy long attributed to a surface Mott insulator driven by enhanced electron correlations. Using density functional theory calculations, we show that this insulating surface instead...

School day physical activity profiles and transitions across the school year: a latent analysis in 8–9 year-old children

Abstract Background School day physical activity (PA) is important for children’s health and development, yet longitudinal evidence on within-year trajectory patterns is limited. Traditional approaches to studying PA change may obscure substantial heterogeneity in how individual...

From feasibility to neuroanatomic validity of remote cognitive smartphone assessments in early Alzheimer’s disease

ABSTRACT Digital health technologies (DHT) offer a promising solution to the timely identification of early Alzheimer’s disease (eAD) to enable early treatment. This study evaluated the feasibility, acceptability, adherence, reliability, and preliminary clinical and content valid...

Foot segments motion during uneven terrain walking and influence on lower limb biomechanics

Abstract Human locomotion has been extensively studied on flat ground; however, everyday walking often occurs on uneven terrain, which poses additional biomechanical challenges. The role of foot segmental mobility under these conditions remains underexplored. This study investiga...

Persistence of immune responses 5 years after vaccination with a single dose of typhoid conjugate vaccine (TCV) in Nepalese children

Background: A single-dose typhoid conjugate vaccine (TCV) has been recommended in endemic settings. Here we report the 5-year immunogenicity results post a single dose of TCV in Nepal. Methods: We conducted a participant and observer-blinded randomised trial (RCT) in Lalitpur, Ne...

Staggered Quadruple-Rutile Oxides as Low-Strain and High-Power Anodes for Lithium-Ion Batteries

Abstract Tunnel-structured oxides provide attractive hosts for lithium-ion storage. However, their application is frequently limited by structural instability or sluggish ion transport at high lithium contents. Here, we demonstrate that the staggered quadruple-rutile framework re...

Navigating mental health care: latine perceptions, barriers, and pathways to engagement

Background: Latine individuals in the U.S. experience similar or higher rates of depression compared to non-Hispanic Whites but remain less likely to receive timely or effective mental health care. While structural and cultural barriers have been well-documented, limited research...

Secondary metabolites from Piper crocatum as natural inhibitors of oral pathogens: in vitro and in silico insights into Streptococcus mutans and Candida albicans

Abstract Background Dental caries is a widespread infectious disease caused by complex interactions between microorganisms in oral biofilms. Streptococcus mutans plays a central role through acid production and glucan-mediated biofilm formation, while Candida albicans enhances bi...

Better mental model, fewer watt-hours? Effects of ecodriving tips on knowledge, action regulation, and driving performance in battery electric vehicles

Supporting users in avoiding waste of valuable resources like energy is a key objective in optimising system design. Particularly in battery electric vehicle (BEV) operation, energy efficiency depends on driver behaviour, i.e., on adequate understanding of energy dynamics. Buildi...

Thermodynamics and Unbinding Kinetics of A22 at Multiple Actin-Binding Sites Revealed by Enhanced Sampling Simulations

Abstract The cytoskeletal protein plays a major role in various cellular processes. Understanding the interactions of small molecules with cytoskeletal protein therefore might help in the development of therapeutics. Employing combined molecular docking, all-atom molecular dynami...

Selective and Efficient Functionalization of P22 Virus-Like Particles Using an Asparaginyl Ligase

ABSTRACT Protein cages provide useful scaffolds for nanoscale engineering due to their highly ordered structures and in vivo self-assembly. These scaffolds are amendable to late-stage conjugation, enabling expansion in functionality. However, many conjugation techniques either la...

Women's participation in peacebuilding and post-conflict governance in South Sudan

Since its independence in 2011, South Sudan has experienced protracted civil conflict and political instability that disproportionately affect women and girls. Despite formal endorsement of international frameworks such as United Nations Security Council Resolution 1325 and the i...

Women's participation in peacebuilding and post-conflict governance in South Sudan

Since its independence in 2011, South Sudan has experienced protracted civil conflict and political instability that disproportionately affect women and girls. Despite formal endorsement of international frameworks such as United Nations Security Council Resolution 1325 and the i...

Conflict, Displacement, and Educational Disruption: A Systems Analysis of South Sudan, 2016–2026

Protracted conflict and large-scale displacement have created a protracted crisis for education systems in several African states. The case of South Sudan represents an extreme example, where systemic collapse has severely constrained access to formal schooling for a generation o...

Conflict, Displacement, and Educational Disruption: A Systems Analysis of South Sudan, 2016–2026

Protracted conflict and large-scale displacement have created a protracted crisis for education systems in several African states. The case of South Sudan represents an extreme example, where systemic collapse has severely constrained access to formal schooling for a generation o...