Research works

Delays in Tuberculosis Care in the Indian Population: A Systematic Review and Meta-analysis

Abstract Introduction: Being harmful to patients, delayed diagnosis and treatment can spread tuberculosis (TB) in the community, posing a significant challenge to TB elimination efforts. This systematic review and meta-analysis aimed to estimate the median delays of TB care and t...

Genetic susceptibility to decompression sickness: molecular mechanisms, genomic advances, and precision prevention strategies

Decompression sickness (DCS) is a multisystem disorder caused by rapid environmental pressure reduction, which causes the dissolved gas in the body to come out as bubbles, and subsequent multi-organ injury. A notable feature is great individual variation in sensitivity. Under ide...

Artificial Intelligence-Assisted Medical Education: Usability, Benefits and Ethical Evaluation

AbstractObjective: The integration of artificial intelligence (AI) into medical education is rapidly increasing; however, gaps remain in terms of learners’ knowledge and ethical awareness. This study aimed to evaluate baseline perceptions of AI among medical students and faculty...

Biomimetic Mustard Seed-Inspired Brush-Free Alternative for Effective Endoscope Channel Cleaning and Decontamination

Inadequate cleaning of flexible endoscope channels remains a major cause of healthcare-associated infections despite established reprocessing protocols. We developed biomimetic carbon balls inspired by mustard seed surface features as a brush-free adjunct for endoscope channel cl...

Spontaneous Expulsion of a Large Submucosal Fibroid in the Postpartum Period: A Report of a Rare Case

Spontaneous expulsion of uterine fibroids is an uncommon clinical event, most frequently described in the postpartum period or after uterine artery embolisation. Expulsion of a very large submucosal fibroid without surgical intervention is particularly rare. We report the case of...

Artificial Intelligence Adoption and Corporate Biodiversity Concern: Evidence from Chinese Listed Firms

Given the growing ecological and economic risks posed by biodiversity loss, this study uses panel data on Chinese A-share listed firms from 2010 to 2023 and employs a debiased machine learning approach to empirically investigate the impact of artificial intelligence (AI) adoption...

Spin-quenching cobalt center for efficient ammonia synthesis derived from oxide mixology

The spin polarization plays a critical role in heterogeneous catalysis by influencing the properties of active sites and thereby altering catalytic performance. However, precise construction of active sites with well-tuned spin states remains challenging. Here we demonstrate to m...

Four Lenses Toward Principle-Based Understanding of Granular Segregation in Dense Flows: Particle, Continuum, Statistical, and Conceptual Approaches

Abstract This review examines the development of concepts and models describing the spontaneous spatial separation—segregation—of dense flowing granular mixtures. Although particle-scale interactions are largely understood and modern discrete element methods can resolve system dy...

L-ShapeDiamond Raman Laser with 35 W at 589nm and Hz-Scale Intrinsic Linewidth

Abstract Narrow linewidth lasers with high power and high beam quality in the visible spectrum are essential for emerging quantum and space technologies. Here, we report significant advances in diamond Raman lasers, generating diffraction-limited yellow light at 589 nm with an ou...

Mapping the General Fertility Rate in Greece: A Time-Trend Nationwide Analysis (1956-2024)

Background: Accurate assessment of fertility rates and their long-term trends is essential for understanding reproductive dynamics, anticipating the healthcare and socioeconomic consequences of demographic change, and informing family planning and population policies. The aim of...

Extracellular and Intracellular Bacterial Compounds in the Synthesis of Inorganic Particles: Silver Nanoparticles

The primary objective of this study was to compare the contribution of cellular and cell-free filtrates of Serratia marcescens ATCC 9986 to the synthesis of silver nanoparticles, followed by a determination of the inhibitory activity on growth of S. marcescens and E. coli of the...

Ten-Year Evaluation of Quality Control Indicators in a Brazilian Human Milk Bank

Background: Human milk banks play a critical role in neonatal care by providing donor human milk when maternal milk is unavailable, particularly for preterm and medically vulnerable infants. Despite global expansion, long-term evaluations of discard rates and quality indicators r...

The evolution of plasticity in drought-related traits in central and edge populations of Mimulus cardinalis

Phenotypic plasticity can influence population persistence, range dynamics, and evolutionary potential in heterogeneous landscapes. If adaptive, plasticity may buffer populations against environmental variability, climate change, and extreme events. Yet, few studies have examined...

Treatment Efficacy of Imidocarb Dipropionate in Saanen Goats Experimentally Infected with Babesia aktasi

Babesia aktasi is a recently discovered species that is highly prevalent in native goats in Türkiye’s Mediterranean region. Although it does not induce clinical disease in local breeds, it causes severe illness in Saanen goats, manifesting with high fever, anemia, hemoglobinuria,...

High-Precision UT1 Prediction with Different Angular Momentum Combination Schemes

Universal Time (UT1) is a core component of the Earth orientation parameters (EOP). High-precision UT1 predictions are essential for satellite navigation, deep-space exploration, and the maintenance of national standard time. Although effective angular momentum (EAM) information...

Want It Like You Mean It: Revisiting Goal Self-Concordance Through the Dissociation of Autonomous and Controlled Motivation in Relation to Meaning in Life

Abstract The Self-Concordance Model posits that autonomously motivated goal pursuit is a primary driver of well-being, yet standard measurement practices often conflate the presence of autonomy with the absence of external pressure via relative difference scores. Using a high-pow...

Liquid Biopsy for Minimal Residual Disease Assessment in Endometrial and Cervical Cancers: Molecular Rationale, Clinical Evidence, and Translational Barriers

Endometrial and cervical cancers can recur from subclinical disease not evident on routine surveillance. This narrative review critically evaluates liquid biopsy for minimal residual disease (MRD) assessment and recurrence monitoring. Post-treatment human papillomavirus (HPV) cir...

The Role of Neurofilaments in Diagnosis and Monitoring of Amyotrophic Lateral Sclerosis

Background: Amyotrophic lateral sclerosis (ALS), the most common type of motor neurone disease (MND), is a devastating diagnosis that often leads to mortality within 2–5 years of symptom onset. Respiratory failure and aspiration pneumonia both associated with respiratory muscle w...

Alcohol exposure induces reversible nucleolar amyloidogenesis

The nucleolus is a dynamic membraneless organelle that rapidly responds to cellular perturbations. Under harsh environmental conditions, it transitions from a ribosome biogenesis center into a dense proteinaceous structure, known as a nucleolar amyloid body (A-body). Although A-b...

Clinicopathologic mismatch in young-onset parkinsonism: Multiple system atrophy masquerading as a neurotransmitter synthesis disorder

BACKGROUND: Multiple system atrophy (MSA) is a progressive adult-onset synucleinopathy that remains difficult to diagnose clinically, particularly in younger patients and during early disease stages. Brainstem nuclei degeneration resulting in reduced monoamines in cerebrospinal f...