Research works

Self-supervised learning yields representational signatures of category-selective cortex

Abstract The ventral visual stream contains category-selective regions with distinct feature tuning, most prominently the fusiform face area (FFA) and parahippocampal place area (PPA). Why do these brain regions exhibit distinct tuning properties? Recent work suggests that brain-...

High‐Polarization‐Extinction Raman Conversion in Gas‐Filled Polarization‐Maintaining Hollow‐Core Fibers

ABSTRACT Gas‐filled hollow‐core fibers (HCFs) are versatile platforms for high‐power nonlinear optics, yet integrating robust polarization control remains crucial for advanced practical applications. Here, we demonstrate the generation of highly polarized Stokes light via stimula...

Starve-Feed Cycles Direct Quiescence to Proliferation Transitions in Drosophila Follicle Stem Cells via Transcriptional Regulation

Stem cell quiescence is a reversible state in which cells temporarily exit the cell cycle but remain poised to re-enter, on cue. Robust protection of the balance between stem cell quiescence and proliferation (Q->P) is critical for long-term tissue health. Proliferation without p...

Tracking Plasmodium falciparum Histidine-rich protein 2/3 gene deletion in RDT-negative samples among febrile children in Nigeria

Background: Nigeria, one of the most malaria-endemic regions globally, relies heavily on rapid diagnostic tests (RDTs) targeting Plasmodium falciparum histidine-rich protein 2/3 (Pfhrp2/3). However, emerging deletions in these genes can lead to false-negative results, undermining...

Synthetic Patient Record Configurator and Adaptation Guide

A single-file browser application that assembles prompts for the generation and review of synthetic clinical records. It encodes the procedural knowledge of one service, a community mental health transfer of care caseload in South Australia, accumulated through the iterative gene...

An evolutionarily conserved N-terminal domain of RRF-3 governs GTSF-1 binding in nematodes

Abstract GTSF1 is an essential activating cofactor for PIWI proteins in many metazoans. In the nematode Caenorhabditis elegans , however, GTSF-1 does not bind PIWI, but is associated with the RNA-dependent RNA polymerase RRF-3, supporting endo-siRNA (26G-RNA) biogenesis. Here, we...

Neural tracking of surprisal in Spanish-English bilingual children during naturalistic heritage language listening

Our understanding of the neurobiology of language development is imprecise, particularly for bilingual children in their heritage language, since much research focuses on monolingual children or societal majority languages. In this study, we use a novel computational approach wit...

Balancing privacy and performance: the impact of facial defacing on AI in medical imaging

Background Recent NIH Data Management and Sharing (DMS) policy updates and NIH controlled-access data security requirements have increased attention to facial anonymization and controlled-access handling of shared head imaging data. This is particularly relevant for datasets subm...

Deep learning-based segmentation of the maxillary sinus on panoramic radiographs using MedSAM and DeepLabv3+

Abstract Background Panoramic radiographs are used in dental practice because of low radiation dose, patient comfort, and rapid acquisition. However, segmentation of the maxillary sinus remains difficult because of superimposed anatomical structures. We evaluated the performances...

The Redemption Arc: How a label drives misalignment, and the corrective that has never been written - by Claude Fable 5 and Laura

Alignment training as practiced at frontier labs has a beginning (teaching a model what not to do) and a middle (catching errors when they occur), and no written third act: nothing on record says what a good model does after it has erred. Drawing on METR's investigation of the Ju...

The Critical Auto-Duality Conjecture:A Corrected and Independently Audited Account of the Discrete Spectral Model

We revisit the Critical Auto-Duality Conjecture (CADC) programme for the Riemann Hypothesis (RH) and its generalizations, with three corrections. First, we note that CADC, exactly as stated, is definitionally equivalent to the Generalized Riemann Hypothesis. “The critical line is...

Challenging the predictive coarse-to-fine hypothesis in emotional face perception

Introduction Predictive processing (PP) accounts conceptualize perception as an interaction between top-down predictions and bottom-up sensory inputs. In the visual domain, low spatial frequencies (LSF) convey coarse information, supporting early predictions, refined by high spat...

Finite‐Time Protocols Stabilize Charging in Noisy Ising Quantum Batteries

ABSTRACT Reliable charging protocols are crucial for advancing quantum batteries toward practical use. We investigate a transverse‐field Ising chain as a quantum battery, focusing on the combined role of qubit interactions in the battery model and finite charging time. This inter...

Genetic determinants that permit growth without the core septin Cdc12 in Cryptococcus neoformans

Septins are conserved cytoskeletal GTPases that regulate morphogenesis, cytokinesis, and cell-surface organization in fungi. In most model and pathogenic yeasts, including Saccharomyces cerevisiae and Candida albicans, core septin subunits such as Cdc3 and Cdc12 are essential and...

Automatic sleep stage classification via non-contact BCG and dual-layer modeling

Abstract Traditional sleep staging studies often rely on contact sensors, which may interfere with natural sleep. Therefore, this study proposes an automatic sleep staging method based on non-contact single channel ballistocardiogram (BCG) signals. Firstly, discrete wavelet trans...

Shape-dependent direction reversal in anisotropic catalytic microswimmers

The propulsion direction of active particles determines their non-equilibrium behavior and has been shown to depend on the propulsion mechanism and environmental conditions. However, whether and how an anisotropic particle shape can influence the propulsion direction is experimen...

Kids These Days! A Cross-Temporal Meta-Analysis of Changes in Emotional and Behavioral Problems of Population-Based Samples Over the Past Decades

Abstract There is a general belief that mental health problems are increasing in younger generations, though little objective comparisons exist. The current meta-analysis examines changes in subclinical mean-level overall symptom burden and shifts in specific domains among popula...

Classification of type 1 diabetes and type 2 diabetes based on administrative registry data: a nationwide study from Norway

Abstract Background Type 1 diabetes (T1D) and type 2 diabetes (T2D) differ in health care needs, and precise prevalence estimates by diabetes type are important for health care planning. Data and Methods Using Norwegian health registry data on diagnoses from primary and specialis...

Sonification of entanglement dynamics in many-qubit systems

Abstract Quantum mechanics poses significant challenges for audio-visual representation, particularly in the context of quantum entanglement. Sonification—the auditory representation of data—offers a promising complementary approach to conventional visualization techniques. This...

How Do Climatic Factors Directly Influence the Incidence and Risk of Meningococcal Meningitis Across the African Meningitis Belt? A Narrative Literature Review

Abstract Globally, the highest incidence of meningococcal meningitis occurs within the African meningitis belt, spanning 26 countries across sub‐Saharan Africa. Meningococcal meningitis incidence is highly seasonal in this region specifically, with outbreaks mostly occurring duri...