Research works

E8 Phi‑Recursive Spectral Cascade for Topological Information Encoding — E8 Intelligence Research

By interposing N layers of the E8 root lattice at 132 Hz intervals and modulating each coupling with the golden ratio φ, we generate a self‑similar spectral cascade where eigenstate phases propagate across the 240 root vectors in a recursive φ‑linked fashion. This cascade creates...

Perceptions of a New Boundary-Crossing Professional in Early Childhood Education and Care

There is a growing trend in which new professional roles complement traditional ones to bridge education, childcare, and social care. In the Netherlands, this is reflected in the introduction of the Pedagogical Educational Professional (PEP) as a boundary-crossing professional in...

Dynamic Learning by Importing: New Insights Using the Local Projections Approach and Matching Techniques

ABSTRACT We study the dynamic effect of learning by importing on the productivity of Ecuadorian manufacturing firms that start to import intermediate inputs. To this end, we apply the local projections methodology to firm‐level data combined with matching techniques. Our results...

Liquidity demand, financing and investment decisions: evidence from the COVID-19 pandemic

Purpose This study examines how firms adjust financing and investment decisions in response to the COVID-19 shock, focusing on whether external financing supports investment or preserves liquidity and how these responses vary across firms with different pre-pandemic characteristi...

On Truth and Reconciliation in America

Declining public trust in democratic institutions reflects a growing belief that powerful individuals evade accountability. Existing mechanisms—including congressional oversight, criminal prosecution, and elections—have proven inadequate to restore public confidence. A national t...

Coordination-Controlled Stability of Pd Single-Atom Catalysts under Electrochemical Conditions

Abstract Single-atom catalysts (SACs) maximize atom utilization and site-specificity for diverse chemical and electrochemical transformations. While activity and selectivity have been optimized through advanced synthetic methods, the electrochemical stability of SACs remains insu...

An Integrated Workflow for Real-Time Chemoenzymatic CMP-Sialic Acid Preparation and a Bioorthogonal Microplate Sialyltransferase Assay (MPSA)

Abstract Sialylation at the terminal ends of cell-surface glycoproteins and glycolipids plays a pivotal role in dictating cellular interactions, human health, and pathological processes. This crucial modification is mediated by a family of twenty distinct human sialyltransferases...

TRANSPORT VOSITALARI DETALLARINING YEYILISHGA CHIDAMLILIGINI OSHIRISH UCHUN MEXANIK ISHLOV BERISH TEXNOLOGIYASINI TAKOMILLASHTIRISH

Maqolada transport vositalari detallarining yeyilishga chidamliligini oshirish uchun mexanik ishlov berish marshrutini takomillashtirish, qo'pol va toza ishlov bosqichlarini ajratish, asbob va kesish rejimlarini tanlash, yakuniy pardozlash hamda sifat nazoratini bir tizimda tashk...

Occupants’ Thermal Sensation in Mixed-Mode Buildings: The Contribution of Thermal Disposition to Interindividual Variability

Interindividual differences in thermal perception remain an important challenge for thermal comfort assessment, particularly in mixed-mode buildings. This study investigates interindividual variability in thermal sensation in a mixed-mode office building in southern Brazil, focus...

Discovery and Design of YTHDF2-Selective and Pan-YTHDF Inhibitors for m6A Binding by the YTH Aromatic Cage

Abstract Recognition of N6-methyl-adenosine (m6A) in the RNA sequences by the YT521-B homology domain-containing protein family paralogs 1–3 (YTHDF1–3) is a dominant layer of myriad cellular regulation. Dysregulated YTHDF paralog expression and activities have been reported in ca...

A Methodological Prototype for Assessing SME Digitalization through Survey Data, Web Scraping, and Human-in-the-Loop Validation

Reliable assessment of the digitalization of small and medium-sized enterprises (SMEs) remains a methodological challenge, as existing studies rely predominantly on survey-based instruments and self-reported information. This article proposes a methodological prototype for evalua...

Brain Gadolinium Biodistribution, Clearance, and Retention Following High-Dose Contrast-Agent Exposure in Mice: A Multimodal Study

We evaluated gadolinium biodistribution, clearance, and long-term brain retention following high-dose gadolinium-based contrast agent (GBCA) exposure in 90 mice. Macrocyclic and linear agents were assessed using particle-induced X-ray emission (PIXE) alongside complementary eleme...

Music Therapy in the Intensive Care Unit and Maternity Ward: Effects of Preferred Music on Behavioral Responses, Emotional State, and Perceived Wellbeing in Conscious Hospitalized Patients — A Pilot Observational Study

Background: Music therapy has been proposed as an inexpensive, non-pharmacological way to improve emotional state and reduce anxiety in hospitalized patients, including those in intensive care. Objective: To describe the self-reported and behavioral emotional changes experienced...

Inner worlds in dissociative identity disorder: An interpretative phenomenological analysis of spatial, relational and agentic organisation

OBJECTIVES: This study examined how adults diagnosed with Dissociative Identity Disorder (DID) experience and make sense of "inner worlds": recurrent, internally experienced spatial settings associated with dissociative parts, events and relationships. DESIGN: A qualitative study...

Orientation tomography of lanthanide-doped nanoprobes by polarization-resolved micro-spectroscopy

Abstract Quantifying three-dimensional (3D) orientation is critical for understanding self-assembly and collective behavior in soft matter and biological systems. Moreover, orientational analysis of anisotropic particles can characterize locally applied forces in fluids. We prese...

Single-Cell Transcriptomic Analysis Reveals Copper Metabolism Heterogeneity and Phenotypic Remodeling in Vaginal Anterior Wall Stromal Cells in Pelvic Organ Prolapse

Pelvic organ prolapse (POP) is a common disease characterized by disordered extracellular matrix (ECM) remodeling of pelvic support tissues. Copper dysregulation drives fibrosis in multiple diseases, whereas its function in POP remains unclear. We analyzed single-cell transcripto...

Relative CT Number as a Quantitative Imaging Biomarker for Differentiating Sinonasal Polyp, Inverted Papilloma, and Squamous Cell Carcinoma: A Preliminary Retrospective Study

Background/Objectives: Unilateral sinonasal lesions may be difficult to characterize on non-contrast computed tomography (CT) because inflammatory polyps, benign neoplasms, and malignant tumors can appear as similar unilateral soft-tissue masses. Non-contrast CT is widely availab...

Twenty-Three Certified Decimals: Rigorous Ground-State Energies, Correlations and a Coupling Curve for the Half-Filled 4×4 Hubbard Model: certificate bundle v1.0.0

We prove the ground-state energy of the periodic, half-filled 4×4 repulsive Hubbard model with t = 1 to at least 23 decimal places at U = 1, 2, 3, 4, 5, 6, 7, 8, 10, 12 and 16: every enclosure has width below 10⁻²⁴. The double occupancy, the spin correlations and the staggered st...

E8 Golden-Root Resonance Filter — E8 Intelligence Research

By mapping the 240 root vectors of E8 onto a 5-dimensional torus with 132 Hz base excitation and phi-weighted coupling, we discover a resonant filtering mechanism where quantum information states become topologically protected against decoherence through synchronized golden-ratio...

Development and Application of a High-Resolution Cryogenic STXM System at the Shanghai Synchrotron Radiation Facility

Abstract Scanning transmission X-ray microscopy (STXM) is an advanced technique for label-free chemical imaging with nanometer-scale spatial resolution which is well suited to studies of complex and heterogeneous materials. For biological and other radiation-sensitive specimens,...