Research works

Build or buy: what’s next for Balmer Lawrie?

Learning outcomes The learning outcomes are as follows: Case overview/synopsis The case “Build or Buy: What’s Next for Balmer Lawrie?” revolves around Balmer Lawrie & Company Limited (BL), a legacy organization navigating its strategic transformation to meet ambitious growth targ...

Disparities in late-stage cancer diagnosis across a multi-site academic health system

Abstract Background Disparities in cancer stage at diagnosis persist despite the availability of screening for several common cancers. We evaluated demographic, clinical, insurance, and neighborhood-level factors associated with late-stage diagnosis in a multisite academic health...

Block vote, open-list proportional representation, and women’s electoral outcomes. Evidence from a quasi-experiment in Polish local elections

Although pioneering research suggested that proportional elections are better for women’s outcomes than plurality rules, research scholarship is accumulating growing evidence that this relationship depends on specific rules. We look at the impact of electoral rules on female part...

A GPRC5B–Fyn signaling axis regulates VRAC activity by targeting LRRC8A

The mechanisms by which physiological signals gate the volume-regulated anion channel (VRAC) remain poorly understood. Here, we identify a GPRC5B–Fyn signaling axis that directly controls VRAC activation by targeting the essential subunit LRRC8A. We found that the orphan G protei...

Acute decompensated aortic stenosis: the final common pathway of a failing system

Abstract The theoretical paradigm for management of aortic stenosis (AS) assumes an early diagnosis, with surveillance until symptoms develop, followed by an elective intervention. In current practice, however, acute decompensation of aortic stenosis (ADAS) leading to hospital ad...

Evaluation of Service Effectiveness of Tram Systems at Stop-Level Using DEA: The Case of Eskisehir, Türkiye

Abstract Public transportation systems are characterized by the simultaneous production and consumption of services, meaning unused capacity cannot be stored. For this reason, the effectiveness of the service provided is a critical performance indicator for public transport opera...

PFEP Preconditioning of Exenatide Solutions: Separating Compounding History from Long-Term Stability

Exenatide is a 39-residue linear peptide whose solution degradation is strongly pH dependent. Published work shows relative stability near pH 4.5, oxidation-dominant loss at pH 5.5–6.5, and increasing deamidation and aggregation at pH 7.5–8.5. This article tests a bounded PFEP pr...

İrade, Manipülasyon ve Modern Mit: Ajax, The Madness

Bu makale, Theodoros Terzopoulos’un Ajax , the Madness adlı sahnelemesini antik mit, irade ve manipülasyon kavramları bağlamında incelemektedir. Çalışma, öncelikle mit kavramının tarihsel dönüşümünü ele alarak modern dünyada ortaya çıkan yeni mitolojik anlatıları ve özellikle neo...

Building Future Learning Ecosystems for Viksit Bharat @2047: A Context-Sensitive Model of Digital Education for Sustainable Development

Building Future Learning Ecosystems for Viksit Bharat @2047: A Context-Sensitive Model of Digital Education for Sustainable Development Dr. Vikash Singh * The aspiration of building a Viksit Bharat by 2047 requires an education system capable of responding simultaneously to techn...

SparseRoute: Structured Sparse Variable Routing for High-Dimensional Multivariate Time Series Forecasting

Forecasting high-dimensional multivariate time series requires models to represent dependencies across variables without making variable interactions prohibitively expensive. Full attention over variable-level tokens has a pairwise cost quadratic in the number of variables; chann...

Reverse Engineering Motion

The Cohesion UFT is built by one method, and this paper states it. The method isreverse engineering: a motion is taken as observed, the mechanical cycle thatproduced it, Tension → Surplus → Torsion → Slip → Acceleration → Maintained Motion,is recovered stage by stage, and the cyc...

Incorporation of Carob Into a High‐Fat Meal Influences Subjective Satiety, Ghrelin and PYY Regulation

ABSTRACT Background Dietary components that influence appetite‐related hormones and subjective satiety may help regulate food intake. Aqueous carob ( Ceratonia siliqua L.) preparations may have a role in postprandial appetite regulation. Aims To investigate the effects of an aque...

Plant Disease and Phytopathogen Research in Central Asia: A Bibliometric Mapping of Research Trends, Collaboration, and Emerging Directions

Plant diseases and phytopathogenic threats pose significant challenges to agricultural productivity and food security in Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan. This study aimed to characterize research development, scientific productivity, collaboration...

Enoxaparin dose assessment in paediatric cardiology patients

Abstract Background: Enoxaparin is a commonly utilized anticoagulant, particularly in infants and children. Recent literature has highlighted the need to initiate enoxaparin at higher doses, especially at younger ages, due to differences in pharmacokinetics and pharmacodynamics....

Flow‐regime transition and flow‐structure‐based scale‐up of Siemens reduction furnaces

Abstract Siemens furnaces are nonlinear CVD reactors in which flow regime evolves as rods grow, while clear scale‐up criteria remain lacking. In this work, flow experiments and simulations are combined to identify hydrodynamic mechanisms. Experiments show a transition from jet‐ca...

Missingness-Aware Spatiotemporal Graph Learning for Urban Sensor Networks: Design Choices and Evaluation Pitfalls

Urban traffic, environmental, and utility monitoring systems generate multivariate sensor streams whose spatial relations and missing-data mechanisms evolve over time. This critical narrative review examines graph-based forecasting and reconstruction in the presence of unreliable...

The Use of Artificial Intelligence to Reduce Teacher Workload: Opportunities and Limitations

This conceptual note examines the use of artificial intelligence as a tool for reducing teacher workload. It focuses on the difference between task automation and actual workload reduction, emphasizing the need to consider the complete teacher workflow, including checking, correc...

Synthesis of Novel 6-N-Aryl/heteroarylethylimidazo[2,1-b]thiazole-3-carboxamides: Bioisosteric Development of Bacillamide Analogues

Marine microorganisms constitute a prolific source of structurally unique secondary metabolites with diverse biological activities. Bacillamide A (1), a thiazole-containing tryptamide alkaloid, was...

Nucleic Acid Therapeutics in an Age of Artificial Intelligence

Artificial intelligence (AI) is transforming how scientific hypotheses are formulated, tested, and applied. Nucleic acid therapeutics can benefit from emerging opportunities but will also face new challenges. AI lowers the barrier to hypothesis generation, increasing the emphasis...

Transforming entrepreneurial intentions to action: a serial mediation model of entrepreneurial alertness and entrepreneurial self-efficacy

Purpose The specific mechanisms that transform entrepreneurs’ intentions into realized entrepreneurial behaviors remain a novel subject of ongoing investigation. Therefore, achieving insights into this process will be critical for expanding theory and informing practices. Further...