Research works
The research papers we track — the newest first. Works with a plain-language summary link to it.
81715 work(s)
- Society & EconomicsOpen access
Political Polarization and Counter-attitudinal Information Consumption and Internalization
Abstract Political polarization can undermine democratic governance by weakening electoral accountability through biases in voter information consumption and processing. A growing literature, primarily from high-income countries, has identified promising interventions to reduce n...
- AI & ComputingOpen access
Variations on the three-sphere: Laves' labyrinth lopped
Abstract Inspired by the structure of srs Laves networks in R3 that underpin the celebrated gyroid surface, we construct a Laves network of identical three-coordinated vertices on S3 with a double twist. This network is a subset of the vertices and edges of the 600-cell, and can...
- Health & MedicineOpen access
Abstract Some Anopheles species that act as malaria vectors are members of species complexes, a concept whereby sibling species cannot be differentiated solely on the basis of morphological characters. Therefore, species complexes represent a major problem in malaria vector contr...
- BiologyOpen access
A permeable protein nanocage enables facile cargo loading and cytosolic protein delivery
Abstract The cytosolic delivery of therapeutic proteins remains one of the most persistent challenges in modern drug delivery. Here, we report the discovery and characterization of an encapsulin-based protein nanocage, QtEnc, with unexpected permeability properties and the abilit...
- Materials & EnergyOpen access
Entanglement by design: symmetry-guided periodic helical assemblies
Abstract In this paper, a selection of elegant, highly symmetric examples of three-periodic tangled nets and filaments is presented. They are constructed via familiar crystal nets using edges as geometric scaffolds for n-fold helical windings. Rather than providing a complete cla...
- BiologyOpen access
Structure-based TCR-pMHC binding prediction and generalization to unseen peptides
Abstract The interaction between T-cell receptors (TCRs) with the peptide-bound major histocompatibility complex (MHC) intricately impacts the functional specificity of T-cell-mediated adaptive immune response. Consequently, implication in immunotherapy has contributed to the eve...
- Physics & SpaceOpen access
Topological robustness of optical skyrmions through a real-world free-space link
Structured light offers a promising solution for the increasing data demands of modern optical networks, opening up degrees of freedom that can be leveraged for greater channel capacity and more bits per photon. However, its implementation is hindered by real-world distortions, f...
- AI & ComputingOpen access
Hardware implementation of photonic neuromorphic autonomous navigation
Reinforcement learning enables artificial intelligence to move beyond perception toward decision-making, but its deployment on conventional electronic hardware is limited by the latency and energy consumption of the von Neumann architecture. Here, we propose a photonic spiking tw...
- Materials & EnergyOpen access
Reliable deep-temperature estimation remains a central challenge in geothermal exploration, particularly in sedimentary–carbonate provinces where borehole data are sparse and vertically imbalanced. These conditions lead to unreliable extrapolation and poor uncertainty characteriz...
- Society & EconomicsOpen access
Over the past two decades, the world has experienced significant and relentless increase in environmental degradation, measured through carbon emissions (CO2). These emissions have been one of the persistent global concerns. South Africa boosts abundance of natural resources and...
- AI & ComputingOpen access
A Survey of Distributed Asynchronous Many-Task Models and Their Applications
Asynchronous many-task (AMT) runtime systems have become an important paradigm for expressing fine-grained parallelism and managing asynchrony in high-performance computing (HPC). Originating from early dataflow concepts, AMTs have evolved to enable dynamic task generation, expli...
- Materials & EnergyOpen access
Photorefractive tuning seeded by third-harmonic light in a diamond photonic crystal cavity
Single-crystal diamond nanocavities have tremendous potential for use in quantum and nonlinear optical technologies. The ability to precisely control their resonant frequencies is essential for many applications, and $\textit{in situ}$ tuning is particularly desirable. In this wo...
- Materials & EnergyOpen access
An orbifold framework for classifying layer groups with an application to knitted fabrics
Abstract Entangled structures, such as textiles and architected materials, are often doubly periodic. Owing to this property and their finite transverse thickness, the symmetries of these materials are described by the crystallographic layer groups. While orbifold notation provid...
- BiologyOpen access
Mendelianization: Concentrating Polygenic Signal Into a Single Causal Locus
ABSTRACT Complex disorders such as depression and alcohol use involve numerous genetic variants, and implicated loci continue to grow with sample size. This proliferation hampers interpretability, as the mechanisms by which so many variants jointly contribute to pathophysiology r...
- Materials & EnergyOpen access
<title>Abstract</title> This study focuses on the synthesis of Nano Zeolite-X from industrial sludge generated by a wastewater treatment plant using a sol-gel method. The fundamental structure of zeolites is an aluminosilicate framework composed of a tetrahedral arrangement of si...
- BiologyOpen access
Tuning Viscoelasticity of Dynamic Covalent Hydrogels for Human Tissue Modeling
ABSTRACT The development of three‐dimensional (3D) in vitro tissue culture models is critical for biomedical research. Hydrogel‐based systems have become preferred scaffolds for 3D models, as they have tunable viscoelastic properties, which are well‐known to influence cell morpho...
- AI & ComputingOpen access
Pragmatics beyond Humans: Meaning, Communication, and LLMs
The paper argues that the emergence of large language models (LLMs) requires a conceptual and methodological reconsideration of pragmatics. It first challenges the traditional positioning of pragmatics within the semiotic trichotomy of syntax, semantics, and pragmatics, suggestin...
- AI & ComputingOpen access
Abstract Background Traditional, complementary, and integrative medicine (TCIM) encompasses a wide range of healthcare practices and is of growing global interest. Preprints, scientific manuscripts posted prior to formal peer review, offer opportunities to address challenges in T...
- BiologyOpen access
Photoperiodic Effects on Early Plant Development in Everbearing and Seasonal Flowering Strawberry
ABSTRACT In recent years, interest in vertical farming systems for strawberry cultivation has increased. Because of the increased costs associated with these systems, optimal use of resources, such as cultivation space and light, is a requirement. This necessitates a detailed und...
- Health & MedicineOpen access
While excess rainfall is associated with mosquito-borne disease because it supports mosquito breeding, drought may also counterintuitively increase disease transmission by altering mosquito and host behavior. This phenomenon is important to understand because climate change is pr...