Research works

Multimodal profiling of pro-inflammatory protease activity identifies caspase-1 as a target for lung cancer interception

Abstract The systemic inhibition of IL-1b, a key mediator of pulmonary inflammation, has been shown to reduce the incidence of lung cancer in patients in years following treatment, but knowledge gaps surrounding its activation and role in the tumor microenvironment are hindering...

Aberrant cerebrovascular reactivity presents as an early biomarker of psychosis susceptibility in patients with 22q11.2DS

Abstract The brain’s ability to regulate blood flow is fundamental to both its function and development. In the context of neurodevelopmental disorders such as schizophrenia, understanding the complex interactions between cerebrovascular health and brain function is crucial for u...

Navigating turbulence: building resilient workforce with dynamic capabilities

Purpose Drawing on the dynamic capabilities perspective, the study aims to move beyond context-dominant explanations by focusing on microfoundational mechanisms through which employees interpret and respond to dynamic work environments. In doing so, it seeks to clarify whether or...

Lineal: An efficient linear algebra library

<title>Abstract</title> This paper introduces Lineal, a new C++20 linear algebra library designed to solve large sparse linear systems arising from PDE discretization on attainable hardware by optimizing runtime and especially memory consumption. Lineal supports matrix-free linea...

The results of a cooperative comic book to promote understanding of cultural differences between Buddhist and Muslim students in southern Thailand

This paper reports the results of a cooperative project to create a storybook to promote knowledge and understanding of cultural differences between Buddhist and Muslim students in the three southern border provinces of Thailand. The action research methodology incorporated four...

Anchors for Homology-Based Scaffolding

Homology-based scaffolding orders contigs based on conserved collinearity of homologous sequences across related species. Existing methods often rely on costly whole-genome alignments or show limited robustness when integrating multiple references. Here, we introduce an anchor-ba...

Investigating Hydrologic Alteration Under Historical and Future Scenarios in the Mobile River and Perdido River Basins Using the Cubist Algorithm

Study RegionMobile River and Perdido River Basins of Alabama, USA.Study FocusThis study investigates the impacts of human activities and climate variability on hydrologic alterations in the Mobile River and Perdido River Basins of Alabama. The research uses a machine learning app...

The Consequences of Promoting Data Literacy among Graduate Students

Abstract We study the impact of a data literacy program on graduate students’ skills and academic outcomes at a large Italian university. The program targets students expected to have weak quantitative skills and provides 120 h of training in data interpretation and processing al...

Tokenizing Loyalty Programs: The Role of Tradability

Problem Definition. Loyalty programs (LPs) are widely used to enhance customer retention and firm profitability. With technological advancements like blockchain, many brands are exploring tokenized LPs. Unlike traditional LPs, where rewards can only be redeemed for future purchas...

Data-driven equation discovery of a sea ice albedo parametrisation

Abstract. In many sea ice models, a single-category, zero layer thermodynamic scheme is employed, in which sea ice albedo is prescribed based on surface types depending on snow cover, surface temperature, or sea ice thickness. The Parkinson and Washington parametrisation (PW79) i...

Risk of febrile neutropenia in breast cancer chemotherapy despite the prophylactic use of pegfilgrastim: a retrospective analysis

<title>Abstract</title> Background Pegfilgrastim, a long-acting granulocyte colony-stimulating factor (G-CSF), is used to prevent febrile neutropenia (FN) in breast cancer patients undergoing chemotherapy. However, a small subset of patients still develops FN and requires hospita...

Stäckel transform, coupling constant metamorphosis and algebraization of quasi-exactly solvable systems

Abstract We extend the application of the notions of the Stäckel transform and the coupling constant metamorphosis to quasi-exactly solvable systems. We discover that for a variety of one-dimensional and separable multidimensional quasi-exactly solvable systems, their sl (2) alge...

Electron Shot Noise on a Current Biased Antenna

Abstract The Parker Solar Probe (PSP) Fields Experiment (FIELDS) uses Radio Frequency Spectrometer (RFS) data and Quasi‐Thermal Noise Spectroscopy (QTN) to determine the temperature and density of electrons in the heliosphere. The FIELDS antennas typically operate with a negative...

Intertwining vectors, and Boltzmann weight matrices, of a Solid-on-Solid model from the 20-vertex model

We initiate a new study on the correspondence between the 20-vertex model and a SOS (Solid-on-Solid) model. In comparison to two previous works of the author which have characterized properties of the transfer, and quantum monodromy, matrices of the 20- vertex model from the pers...

The comprehensive detection of hemoglobinopathy variants via long-read sequencing

ABSTRACT BACKGROUND The genetic complexity of hemoglobin genes, characterized by high GC content and homologous sequences, poses significant challenges for detecting hemoglobin variants in clinical settings. METHODS A long-read indexed PCR method utilizing the novel CycloneSEQ na...

Global Boundedness Induced by Asymptotically Non‐Degenerate Motility in a Fully Parabolic Chemotaxis Model with Local Sensing

ABSTRACT A fully parabolic chemotaxis model of Keller–Segel type with local sensing is considered. The system features a signal‐dependent asymptotically non‐degenerate motility function, which accounts for a repulsion‐dominated chemotaxis. Global boundedness of classical solution...

The Dynamic Distribution in the Fixed Cost Model: An Analytical Solution

I derive an analytical solution to the Kolmogorov forward equation for a fixed cost model. This is a challenging PDE, because the dynamic distribution depends on the flow of resetting agents, which is endogenously determined by the distribution itself. I show there is a shortcut...

Accessible Complexity Bounds for Restarted PDHG on Linear Programs with a Unique Optimizer

The restarted primal-dual hybrid gradient method (rPDHG) has recently emerged as an important tool for solving large-scale linear programs (LPs). For LPs with unique optima, we present an iteration bound of [Formula: see text], where [Formula: see text] is the target tolerance, [...

The hidden cost of illness: exploring the relationship between seasonal respiratory illness, self-efficacy, and academic achievement of undergraduate science students

<title>Abstract</title> <bold>Background</bold> Seasonal respiratory illnesses (SRIs), including COVID-19, have significantly disrupted university students' academic experiences. This study examines the impact of SRIs on key academic factors such as attendance, self-efficacy, and...

A conceptual model for the initiation of the manufacturing relocation process

Purpose There is a knowledge gap in the literature on how firms initiate the manufacturing relocation process and how decision-makers can adopt a more proactive approach to relocation. This paper aims to address these gaps by presenting a conceptual model for the initiation of th...