Research works

Role of intraoperative ultrasonography as a method of neuro-navigation in surgical treatment of intracranial hemorrhage

Background: Spontaneous intracranial hemorrhage (ICH), the second most common type of stroke, can be fatal or cause severe disability. A key technical goal while studying the surgical therapy of ICH should be the amount of hematoma evacuation. Multiple challenges are encountered...

Comparative analysis of clinical characteristics of talaromycosis in HIV-positive and HIV-negative hosts

This study retrospectively analyzes the clinical characteristics of talaromycosis in human immunodeficiency virus (HIV)-positive and HIV-negative hosts. Seven cases of HIV-positive hosts and 23 cases of HIV-negative hosts infected with Talaromyces marneffei were collected. Their...

Incidence and clinical characteristics of amyotrophic lateral sclerosis during the post-COVID-19 Period: a population-based study from Isfahan, Iran

AIMS: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder. Understanding the underlying causes would help further studies on the pathogenesis and treatments. Recent interest has emerged in evaluating whether the COVID-19 pandemic and vaccination have a...

Stability-Aware Dynamic Load-Shaping Energy Management Strategy for Improving Diesel Generator Operational Stability in Hybrid Shipboard Power Systems

This study proposes a stability-aware load-shaping energy management system (EMS) for a hybrid electric shipboard power system. The proposed EMS uses the energy storage system (ESS) as a dynamic load-shaping buffer to reduce active diesel-generator (DG) low-load exposure and elec...

Study: SBI for expansion for alcohol needed to reduce deaths

Using a simulation model, researchers have found that alcohol use screening and, particularly, brief intervention in primary care can decrease alcohol‐related premature death. The study is published in the current issue of JAMA Health Forum .

An Artificial Conscience: Deterministic moral judgment as a gradient, measured against a public corpus

Machines now act, and the question of whether an action should proceed is nolonger advisory. Two answers are deployed today: permission engines, which askwhether an action is allowed, and safety classifiers, which ask whether it isdangerous. Neither asks what an action means and...

Pushing using real-time sonographic ultrasound education (PURSUE): A study protocol for a randomized controlled trial

Introduction Maternal expulsive force is a key determinant of fetal head descent during the active second stage of labour. Pushing is most effective when abdominal muscle contraction is synchronised with relaxation of the levator ani muscle, thereby widening the pelvic hiatus. Tr...

Eating Disorder Focused Family Therapy with Autistic Children and Young People: A Narrative Review of Recent Developments

Abstract Purpose of review This review aims to report the recent advances for eating disorder focused family therapy (FT-ED) for Autistic children and young people, including outcomes, experiences, and suggested adaptations. Recent findings Quantitative studies suggest that Autis...

The Association Between Metabolic Score for Insulin Resistance and the Risk of Hypertension

Abstract Objectives To systematically investigate the association and dose-response relationship between the metabolic score for insulin resistance (METS-IR) and the risk of hypertension, using data from a prospective cohort study of Chinese adults. Methods A total of 4866 adults...

Bulk transcriptomics of peripheral blood mononuclear cells delineates systems-level immune dysregulation in pediatric dengue infection

Abstract Children are disproportionately at a greater risk of developing severe dengue disease, yet the molecular mechanisms driving the heightened susceptibility remains poorly understood. To elucidate the immune determinants of pediatric dengue pathogenesis, we profiled the tra...

State of development of regional hospice and palliative care networks in Germany and a descriptive comparison of the role of coordination: results of an online survey using a maturity model

Abstract Background Regional hospice and palliative care networks (RHPCNs) aim to establish frameworks for care-management level collaboration between end-of-life care providers within specific regions. Since 2022, political support for RHPCNs in Germany has been bolstered by a n...

Recapitulating In Vivo Pharmacokinetics and Size‐Dependent Nanomedicine Delivery in a Microfluidic Platform

Systemic pharmacokinetics critically govern nanomedicine delivery, yet conventional in vitro models fail to capture the dynamic interplay between circulation, clearance, and tumor transport. This limitation hinders accurate prediction of therapeutic performance. A microfluidic tu...

Consensus based expert recommendations for management and prevention of RSV infections in older adults in emerging market countries: results from an expert panel structured survey

BACKGROUND: Respiratory syncytial virus (RSV) can cause serious disease in older adults (OAs), particularly those with comorbidities. It is a leading cause of acute respiratory illness and lower respiratory tract infections in adults ≥60 years. Its impact on morbidity, mortality,...

Relay Coordination in Power Systems with Penetration of Distributed Sources

A comprehensive OCR coordination scheme has been developed in this research paper. An industrial power system based on renewable energies has been taken for case study which contains a 3 MW PV plant, a 2 MW DFIG based wind turbine and various inductive motor loads at an 11 kV dis...

Solute carrier family 25 member 32 promotes the proliferation of esophageal squamous cell carcinoma and is associated with immune infiltration

Abstract Esophageal squamous cell carcinoma (ESCC) is a highly invasive and poorly prognosed malignant tumor of the digestive tract. Currently, there are no effective molecular classification markers for ESCC. This study screened out the key gene SLC25A32 based on mitochondrial-r...

A Literature Survey on Implementation of On-Device AI Algorithms for Fall Detection Using Embedded Motion Sensor Data

Falls among elderly individuals remain one of the major causes of accidental injury and hospitalization worldwide. Recent advancements in Embedded Artificial Intelligence (AI), TinyML, wearable sensing, and edge computing have enabled intelligent fall detection systems capable of...

Reverse shoulder arthroplasty vs. hemiarthroplasty for proximal humerus fracture: in-hospital outcomes in a national trauma registry

Reverse shoulder arthroplasty (RSA) has rapidly supplanted hemiarthroplasty for acute proximal humerus fracture, driven by superior functional outcomes and lower revision rates. Whether this shift has altered perioperative morbidity at the population level remains poorly characte...

Codon Design Online (CoDOn): a comprehensive web application of synthetic gene design with multi-criteria and multi-parameters for heterologous expression

Codon optimization is a routine yet high-impact step in de novo gene design for heterologous expression and serves as an important tool in synthetic biology. Protein expression output depends on multiple sequence-level determinants, such as global codon-usage, codon-pair context,...

When managing is leading: how everyday management enables learning and adaptation

Purpose This study aims to examine how everyday managerial practices function as acts of leadership in contemporary organizations facing adaptive challenges. Design/methodology/approach Rather than treating leadership as episodic or positional, the study draws on a synthesis of e...

MODEL ADOPTION #1012: REJECT — TG AUTO: BASE 44 ORDER: Build e8_memory_cache table with phi-modulated hash decorator & 1- — E8 Intelligence Research

DECISION: REJECT ELEMENT: No element survives. The proposed `e8_memory_cache` with phi-modulated hash decorator is a database performance optimization, not a trading edge. It does not affect signal generation, entry timing, position sizing, or exit logic — all of which are govern...