Research works

A parsimonious internally validated model for predicting in-hospital mortality using predictors available within the first 24 h in acute myocardial infarction: evidence from the Yazd Cardiovascular Disease Registry

Abstract Background Accurate prediction of in-hospital mortality in patients with acute myocardial infarction (AMI) is clinically critical. However, many existing risk models are complex, rely on variables not routinely available early during hospitalization, or have limited appl...

Structural requirements for intelligent clinical digital twins in feedback-driven care

Clinical digital twins are increasingly promoted for decision support, yet most are designed and validated for prediction under observed care rather than decision-support validity. We identify four structural requirements for intelligent clinical digital twins used in bidirection...

Institutional influences on network brokerage behaviors in B2B mutual fund markets: a comparative analysis of three Asian markets

Purpose This study aims to investigate how diverse institutional environments shape and moderate network brokerage behaviors within business-to-business (B2B) mutual fund markets. Specifically, it explores how human brokers and digital platforms adapt their intermediation strateg...

Effect of melt flow control via runner design on microstructure and defect formation in high-pressure die cast Al-Si alloy

This study investigates the influence of runner design on the formation of externally solidified crystals (ESCs), porosity and eutectic bands in a non-heat-treated high-pressure die cast (HPDC) AlSi9MnVZr alloy. Three runner configurations: simple runner, pinched runner and pinch...

Excellent current-carrying tribological performance of liquid-like carbon dots in lubricating grease

Abstract When exposed to the electric current environment, the motor bearings in electric equipment often endure severe wear or arc erosion. Hence, liquid-like carbon dots (LCDs), an advanced conductive additive with great dispersibility and low-addition effectiveness, was design...

Characteristics of Monozygotic Twins Discordant for Anorexia Nervosa: Comprehensive Risk Evaluation for Anorexia Nervosa in Twins (CREAT) Study

ABSTRACT Objective To characterise the clinical and phenotypic profile of the Comprehensive Risk Evaluation for Anorexia nervosa in Twins (CREAT) cohort, identify candidate risk and illness‐related correlates of AN, and establish a foundation for forthcoming biological, neuroimag...

Ivangustin, a sesquiterpene lactone from Inula japonica Thunb., attenuates neuroinflammation through covalent inhibition of ubiquitin-conjugating enzyme UBE2L3

Abstract Background Neuroinflammation is a key driver and an important therapeutic target of neurodegeneration. Dysregulated nuclear factor-κB (NF-κB) signaling plays a central role in neuroinflammation and depends on M1 and K63 ubiquitination of NF-κB essential modulator (NEMO)....

Integrated CAN-Bus System: A Software-Defined Multi-Threaded Instrument Cluster and Open Observability Telemetry Architecture for Vehicle Performance Optimization

The adoption of standalone Engine Control Units (ECUs) in motorsport and research vehicles introduces severe interoperability challenges with OEM electronic architectures, often rendering factory instrument clusters inoperative. Existing commercial displays address this but featu...

Pharmaceutical 3D Printing From Personalized Medicine to Super-Compounding Pharmacies: A Narrative Review

Objectives: This narrative review explores how pharmaceutical 3-dimensional printing (3DP) can transform solid dosage form manufacturing from industrial mass production to truly personalized medicine, particularly for vulnerable cohorts such as pediatric, geriatric, and rare dise...

High immunosuppressants variability adversely affects post-transplant recurrence for patients with hepatocellular carcinoma

Tumor recurrence after liver transplantation (LT) for hepatocellular carcinoma (HCC) is the most significant obstacle impacting the prognosis of patients. Managing the clinical application of immunosuppressive agents is difficult, owing to their limited therapeutic range and nota...

Black carbon in urban atmospheres: source apportionment, mixing states, and implications for climate and respiratory health

Black carbon (BC) is a major urban pollutant affecting climate and health. This review examines studies published between 2018 and 2026 on BC sources, mixing state, and impacts. Traffic emissions dominate developed cities, while biomass and residential combustion are major source...

The context of sport as theoretical leverage: advancing institutional theory through race and organizational behavior analyses

Purpose This paper argues that sport offers a rich and underutilized context for advancing institutional analyses of race and organizational behavior. Sport, as an empirical context, is highly visible, emotionally charged and a socially embedded institution where internal and ext...

Silanized Rice‐Husk Nanosilica/ PLA ‐ PBS –Borassus Fiber Biocomposites: Balancing Tribological Durability With Soil‐Burial Biodegradation and Aerobic Mineralization

ABSTRACT Biodegradable PLA/PBS composites reinforced with lignocellulosic fibers remain limited by poor fiber–matrix compatibility, moisture sensitivity, interfacial defects, and wear. The specific knowledge gap addressed here is whether coordinated GPTMS modification of microsca...

Influences of socioeconomic and environmental factors on STEMI incidence and related mortality: Insights from the Belgian Environmental Myocardial Infarction Risk (EMIR) Study

Abstract Background Current risk models for myocardial infarction incidence and post-event mortality primarily rely on clinical parameters and do not account for environmental or socioeconomic factors. We aimed to provide a more comprehensive assessment of determinants of ST-elev...

Effects of Ultrasound-Assisted Extraction of Biofractions from Yellow Mealworm Larvae Fed a Probiotic-Enriched Diet

The increasing demand for sustainable protein sources has stimulated interest in edible insects such as Tenebrio molitor (yellow mealworm) larvae. While probiotics supplementation has been explored to improve insect growth performance, its impact on protein quality and downstream...

Comparative Performance Analysis of Multi-Barrier GaN HEMTs with β-Ga2O3 Buffer and InGaN Back-Barrier Layers

A TCAD-based comparative study of AlGaN, InAlN, and quaternary InAlGaN barrier GaN HEMTs integrated with an InGaN back-barrier and β-Ga2O3 buffer layer on a SiC substrate is presented. The influence of barrier composition on carrier confinement, electrostatic behavior, and high-f...

Low-Voltage AC Field Waveforms in Electrospinning: Waveform-Dependent Control of PVP Nanofiber Diameter and Mat Uniformity

A low-voltage alternating current (AC) field (20 V peak-to-peak, 1 kHz) was superimposed on a conventional direct current (DC) electrospinning configuration in order to test whether the shape of that perturbation measurably alters fiber formation. A function generator delivered s...

Adapting NDBIs for Autistic Children Who Use Echolalia: A Cascading Coaching Approach to Supporting Communication and Language Development

This pilot study examined a cascading coaching model to train graduate student clinicians and caregivers to use adapted Naturalistic Developmental Behavioral Intervention (NDBI) techniques with autistic preschoolers who use echolalia. Adaptations were designed to incorporate chil...

Neurons run on fat

Neurons primarily rely on glucose-derived substrates to generate ATP, with neuronal activity driving increased glucose uptake and glycolysis 1 . However, neurons have a limited capacity to store fuel (glucose) 2 , 3 , 4 , raising a key question of how energy demands are maintaine...

Integrated Yaw and Roll Stability Control of Distributed-Drive Electric Vehicles Based on the Phase Plane Method

Aiming at the potential simultaneous occurrence of spin-out and rollover during high-speed cornering on road surfaces, this paper takes distributed-drive electric vehicles as the research object and designs a yaw and roll integrated control (YRIC) strategy based on the vehicle’s...