Research works

Nanoplate Digital PCR for Identification of α0-Thalassemia (SEA Deletion): Carrier Screening and Possible Application to Prenatal Diagnosis

The Southeast Asian deletion (--SEA), the most prevalent α0-thalassemia mutation in Southeast Asia, is a major target of regional thalassemia prevention programs. Coinheritance of α0-thalassemia with other hemoglobinopathies, particularly hemoglobin E (Hb E), complicates routine...

Through the door or the looking glass? Comparing in-person and virtual hospital clowning impact on parents’ anxiety and children’s negative emotions

Abstract This study compared in-person and virtual hospital clown interventions to a control group, assessing children’s negative emotions and parental anxiety before and after intervention. Ninety-five children (52 girls, aged 4–17, M = 9.75) and their parents were assigned to i...

Environmental exposures and risks for the idiopathic inflammatory myopathies and its phenotypes: a narrative review

Purpose of review The delineation of myositis-specific autoantibody (MSA) subgroups over the past two decades has reframed environmental research in idiopathic inflammatory myopathies (IIMs), making it plausible to examine discrete exposure-phenotype pairings within serologically...

Spermatocytic Tumor Arising in a Cryptorchid Testis: A Case Report and Narrative Review

Background: Spermatocytic tumor (ST) is a rare non-GCNIS-derived testicular germ cell neoplasm that predominantly affects older men and generally follows an indolent course. Its occurrence in a cryptorchid testis is exceptionally uncommon. Methods: A narrative literature review w...

Breaking the Carnot Limit with a Gravity-Driven Work Cycle

Background Classical thermodynamics and the Carnot cycle assume uniform, field-free media, relying on temperature gaps, artificial compression and cold heat sinks, with efficiency capped by the Carnot theorem. Conventional theory overlooks spontaneous pressure-temperature gradien...

Synergistic Enhancement of Luminescence Dissymmetry Factor and Quantum Yield via Hybrid Copper(I) Iodide Cluster and Cellulose Nanocrystal Bilayer Films

ABSTRACT Circularly polarized luminescence (CPL) has emerged as a cornerstone technology for next‐generation chiral photonic applications. However, a fundamental trade‐off between the luminescence dissymmetry factor ( g lum ) and photoluminescence quantum yield (PLQY) has remaine...

Insecticide resistance in larval populations of Aedes aegypti and Aedes albopictus from Panama

The control of Ae. aegypti and Ae. albopictus is the most effective strategy for preventing the transmission of the arboviruses DENV, ZIKV, and CHIKV. However, insecticide resistance threatens the sustainability of vector control programs. Monitoring insecticide resistance enable...

How Non-Performing Loans Reshape Bank Liquidity Determinants: Evidence from the European Union

(1) Background: The aim of this paper is to identify a critical non-performing loans threshold and to examine whether the impact of macroeconomic and bank-specific determinants on bank liquidity differs across credit-risk regimes. (2) Methods: Using annual panel data for EU count...

Organic Solar Cells with Metallogel/LiF Cathode Double Layers and Non-Fullerene Acceptors

Metallogels are a new class of soft materials formed by supramolecular interactions between metal ions and low molecular weight gelators(LWMGs), and are well known for their semiconducting nature, especially transition metal-based ones. Recently, it has been shown that some of th...

Creative Industries in the EU-27 Intersectoral Network: A Relatedness-Based Input–Output Analysis

Both researchers and policymakers increasingly recognize the importance of creative industries within the broader economy. While previous studies have primarily examined their innovation activities and knowledge diffusion through labor mobility and relatedness, considerably less...

Local IGF-1 and Akt/mTOR signaling in skeletal muscle of lubabegron-supplemented finishing steers

Abstract Lubabegron (LUB) is a β-adrenergic agonist/antagonist approved for reduction of ammonia gas emissions in feedlot cattle; improvements in growth and carcass yield have also been reported, although the underlying mechanism remains unresolved. Thirty-two Angus-influenced st...

Deep Learning-Based Hydrothermal Scheduling Integrating Wind Power and Pumped-Storage Hydropower for Low-Carbon Economic Dispatch

The increasing penetration of variable renewable energy sources into electric power systems requires advanced optimization tools to address the complexity of hybrid hydrothermal scheduling while minimizing generation costs and carbon emissions. This study investigates the applica...

SciRep: A Ranking-Aware Representation Model for Scientific Text

Existing scientific text representation methods based on contrastive learning typically adopt a binary classification paradigm of positive and negative samples, which struggles to capture the complex, hierarchical semantic similarity relationships inherent in scientific texts. To...

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecour...

Food Security Versus Environmental Health: The Nitrogen Dilemma

ABSTRACT Nitrogen is an essential element for plant growth and, consequently, crop production. However, the cycling of nitrogen in the environment can have negative effects. Here, we review the historical development of scientific and public awareness of these effects and the inf...

Comparative Genomics of Stress-Associated Gene Family Copy Number Variation in Chlorophyte Microalgae

Abiotic stresses severely limit agricultural productivity and have stimulated growing interest in microalgae as sources of stress-resilient traits and biostimulants. However, comparative genomic assessments integrating multiple stress-associated gene families across chlorophyte g...

Leveraging Google location history data to assess the impact of activities, locations, and time spent in green space on mental health during the COVID-19 pandemic

Abstract The COVID-19 pandemic led to stay-at-home orders, resulting in sudden changes in movement patterns and social restrictions that impacted mental health. This study examined changes in individual behaviors during the pandemic using detailed smartphone-based activity data a...

A Study on the Ball Burnishing Main Regime Parameters’ Impact on Manufacturing Lubricating Groove Widths Formed on the Friction Surfaces of Multilayer Connecting Rod Liners

The present research investigates the optimization of ball burnishing (BB) process parameters to create regular lubricating grooves on multilayer connecting rod liners to prevent engine seizure. The study utilized a Taguchi L9 fractional orthogonal array to evaluate the impact of...

Differentiation of Plant-Pathogenic Fungi in Soybean Seeds Using Hyperspectral Sensors

Hyperspectral sensors have emerged as a promising approach in the study of plant diseases. The objective was to distinguish between healthy and inoculated seeds, and also to distinguish between genera of plant-pathogenic fungi in soybean seeds, using hyperspectral sensors combine...

In vitro study and in silico reveal Teucrium Polium L. methanolic extract as an apoptosis inducer and a potential Bcl-2 inhibitor for breast cancer

Therapy of breast cancer (BC) overexpressing the pro-survival protein Bcl-2 remains a major clinical challenge. The discovery of natural anticancer drugs with potential as Bcl-2 inhibitors has generated increasing interest. The medicinal plant Teucrium polium L. (TPL) exhibits ph...