Research works

Ex vivo cardiac simulator platforms for personalized cardiovascular diagnostics and intervention planning

Ex vivo cardiac simulators are an ideal solution to the rising burden of cardiovascular disease by leveraging native tissue to replicate patient hemodynamics with high fidelity. Their continued evolution necessitates a review of the technology’s development and analysis of simula...

A narrative review of progress and lessons from a decade of implementing infection prevention and control in Sierra Leone following the Ebola epidemic

Infection Prevention and Control (IPC) is essential for resilient health systems and emergency preparedness. In Sierra Leone, inadequate IPC practices during the 2014–2016 West Africa Ebola epidemic catalysed the establishment of a national IPC programme. This review examines a d...

Monomer-biased manufacture of industrial-scale colloidal photonic films

Complex functions in nature arise from the ordered assembly of simple building blocks. Transformation of colloidal aggregates into industrial-scale photonic crystals under rapid ambient conditions remains challenging owing to high energy barriers and limited assembly control. In...

In Situ Thermal Performance Assessment of a Wood–Aluminum Window: Case Study of Spatial Variability, Dynamic Effects, and U-Value Accuracy

This paper presents an experimental evaluation of the thermal performance of a wood–aluminum window installed in a timber building exposed to real climatic conditions. The assessment is based on long-term in situ measurements of heat flux and temperature variations. The aim of th...

Oxygen Serves as an Electron Acceptor for Efficient Photocatalytic Acetylene Hydrochlorination in Seawater

ABSTRACT The photocatalytic acetylene hydrochlorination with H 2 O as hydrogen source and Cl – as chlorine source in seawater is a highly promising alternative to traditional thermocatalytic acetylene hydrochlorination, but seriously suffers from poor performance due to the rapid...

Applications of Probiotics in Soy Milk Fermentation: Flavor Improvement, Texture Optimization, and Functional Component Transformation

Probiotic fermentation technology has emerged as an effective biotechnological strategy to enhance the sensory quality and functional properties of plant-based foods. Among dairy alternatives, soy milk has attracted considerable attention due to its rich nutritional profile. Howe...

Bulūgh and Bioethics: Islamic Criteria for Puberty and its Contemporary Implications

In Islamic law, Bulūgh (puberty) separates childhood from adulthood, yet English-language scholarship on it is sparse and fragmented. We reviewed primary juristic compendia of the four canonical schools of Islamic jurisprudence (Ḥanafī, Mālikī, Shāfiʿī, Ḥanbalī), synthesized biom...

E8 Root Vector Phase-Locking in Spin-½ Nuclear Magnetic Resonance — E8 Intelligence Research

The 240 root vectors of the E8 lattice serve as the discrete optimal configuration states for spin-½ nuclei, where Phosphorus-31 precession undergoes quantized jumps between adjacent root-vector orientations. This phenomenon creates a geometric phase-locking effect, where the 132...

CLDN18 as a novel junctional biomarker enhancing multi-gene classification of pancreatic cancer

Pancreatic adenocarcinoma (PAAD) remains one of the most lethal cancers, largely due to the lack of reliable diagnostic biomarkers. Through integrative transcriptomic and proteomic analyses, we evaluated a four-gene signature comprising CLDN18, CEACAM5, FUT3, and FUT6, capable of...

Outdoor Environmental Comfort, Public-Space Use and Perceived Sociability Among Ageing Populations: Integrating Field Surveys and Microclimatic Simulations

Outdoor environmental comfort is increasingly relevant amid climate change and population ageing because it affects well-being, behaviour and public-space use. However, the relationship between microclimatic conditions, environmental perception, and public-space use among older a...

GOPeMAN — Version 2.0: Relational Physics Research Proposal + Rapid Cosmological Formation Hypothesis (RCFH)

This paper proposes a specific, falsifiable statistical test for a relational term between the two members of a binary compact-object system. The core proposal is to test whether a reproducible joint contribution remains after established physics and observational effects are acc...

Stereographic Projection Unifies All Pythagorean Triples via Euclid's Formula — E8 Intelligence Research

FINDING: Rational parametrization of the unit circle via stereographic projection is the complete generative source of all Pythagorean triples, equivalent to Euclid's formula. MATH: - Unit circle: \(x^2 + y^2 = 1\). - Stereographic projection from point \((-1,0)\): line through \...

Dissecting contributions of directional and balancing selection to trajectories of mitochondrial haplotype evolution in Drosophila melanogaster

Abstract Emerging evidence suggests mtDNA haplotypes contribute to fitness variation and local adaptation, with directional thermal selection and negative frequency-dependent selection shaping haplotype diversity. However, their interplay remains unexplored. We conducted experime...

Practical antimicrobial TDM (PAT) of vancomycin in Japanese emergency and critical care units: Concentration overestimation and correction using scaling factors

OBJECTIVES: i) To improve the accuracy of initial dosing design in vancomycin therapeutic drug monitoring (TDM) using a free web application of practical antimicrobial TDM (PAT) for vancomycin, ii) to identify patient subgroups in emergency and critical care settings with overest...

Counterfeit Intimacy

AbstractThe paper introduces the concept of "Counterfeit Intimacy" (CI): the emission, by conversational artificial intelligence systems, of relational signals that are authentic in form, but lack the relational state that such signals conventionally indicate. Unlike existing app...

I2M: a box-based detection framework for molecular structure recognition from images

Accurate recognition and reconstruction of chemical structures from molecular images is critical in cheminformatics, with applications spanning drug discovery, materials science, and patent analysis. However, much of this chemical matter exists in implicit forms that are not dire...

Machine Learning-Based Prediction of Machinability Responses in Meso-Scale Ultrasonic Vibration-Assisted End Milling (UVAEM) of Inconel 718 Superalloy: A Comparative Study of GPR, SVR, Random Forest, and Ridge Regression

Meso-scale ultrasonic vibration-assisted end milling (UVAEM) is an advanced manufacturing technique. UVAEM of Inconel 718 superalloy presents significant modeling challenges due to complex thermo-mechanical interactions and meso-scale size effects. This study introduces a machine...

The mechanism of fashion consciousness influencing Gen Z’s Willingness to continue using slow fashion apparel in a sustainable context

To explore the mechanisms underlying Gen Z consumers’ willingness to continue using slow fashion apparel, this study constructs a conceptual model based on SOR theory. The model considers personal and social fashion consciousness as stimulus variables, aesthetic, emotional, socia...

Trajectory Controllability and Ulam–Hyer's Stability for Higher‐Order Coupled Hilfer Fractional Neutral Stochastic Integro‐Differential Equations via Measure of Non‐Compactness

ABSTRACT The present manuscript investigates the controllability and stability of coupled higher‐order Hilfer fractional neutral stochastic integro‐differential systems (HFNSIDSs) driven by fractional Brownian motion (FBM). To the best of our knowledge, the study of coupled highe...

Preliminary Desktop Screening of Selected Polish Inland Ports in the Oder Waterway System for LNG-Fuelled Vessels in the Context of Sustainable Development: An Ordinal Multicriteria and Bottleneck Approach

Within the broader sustainable-development transition of inland navigation, liquefied natural gas (LNG) may serve as a transitional fuel, but its use requires appropriate berthing conditions, controllable candidate transfer areas, landside access, operational procedures, and emer...